CHD8

Chromodomain-helicase-DNA-binding protein 8 · Q9HCK8 · CHD8 on Sugi Atlas →

0 patent compounds predicted against CHD8, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to CHD8 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Compared the Efficacy and Safety of CDOP Combined With Chidamide and CDOP in de Novo Peripheral T Cell Lymphoma Patients PHASE3UNKNOWN
PhII 5-Azacytidine Plus Valproic Acid and Eventually Atra in Intermediate II and High Risk MDS PHASE2COMPLETED
Trial of the Histone-Deacetylase Inhibitor ITF2357 Followed by Mechlorethamine in Relapsed/Refractory Hodgkin's Lymphoma PHASE1/PHASE2COMPLETED
An Open-Label, Proof of Consent Study of Vorinostat for the Treatment of Mdoerate-to-Severe Crohn s Disease and Maintenance Therapy With Ustekinumab PHASE1/PHASE2RECRUITING
Evaluation of the Safety and the Tolerability of a Combination of Two HIV Inducers in Patients With Undetectable Viral Load PHASE1COMPLETED
Study of Cytolytic Viral Activation Therapy (CVAT) for Recurrent/Metastatic Nasopharyngeal Carcinoma PHASE1UNKNOWN
Studying The Role of Key Epigenetic Mediators in Breast Cancer Patients nanRECRUITING
Global Profiling of Gene and Protein Expression Associated With Coronary Heart Disease Reversal nanCOMPLETED
ABC-CT Pre-School Feasibility Study nanCOMPLETED
The Autism Biomarkers Consortium for Clinical Trials: Confirmation Study nanCOMPLETED
Genetics of Congenital Heart Disease nanRECRUITING
Accelerated Aging in Newborns and Adults With Congenital Heart Disease nanUNKNOWN
Research for Genetic Factors Involved in Congenital Dislocation of Hip: Genome-wide Association Study in Grand West France nanCOMPLETED
Genes Associated With Development of Pulmonary Arterial Hypertension in Patients With Congenital Shunt Lesions nanRECRUITING
Chromosome 18 Clinical Research Center nanRECRUITING
The Sequencing for Detection in Congenital Heart Disease (SD-CHD) Study nanRECRUITING
UTHealth Turner Syndrome Research Registry nanRECRUITING
Diagnosis of RSTS: Identification of the Acetylation Profiles as Epigenetic Markers for Assessing Causality of CREBBP and EP300 Variants. nanUNKNOWN
PET-MRI F-DOPA Activity in the Mesocorticolimbic System and Depressive Symptoms in the Prediction of Treatment Compatibility nanUNKNOWN
Studying Genes in Samples From Younger Patients With Relapsed Acute Lymphoblastic Leukemia nanCOMPLETED
Antenatal Investigation of Fetuses With Complex Congenital Heart Defects Using multiOMICS nanRECRUITING
Patients With RETT Syndrome nanUNKNOWN
dbGaP Protocol: The Pediatric Cardiac Genetics Consortium (PCGC) nanCOMPLETED
PHF19 Gene Expression and EZH2 Gene Deletion in Acute Myeloid Leukemia nanUNKNOWN
Effect of Exercise Gene Expression and Histone Modifications in Patients With Hemiplegia nanRECRUITING
The Belgian Genome Resource to Resolve Rare Diseases nanCOMPLETED
Clinical and Genetic Analysis in Congenital Hypothyroidism Due to Thyroid Dysgenesis. nanCOMPLETED
Effect of Adenovirus E1A Oncogene on DNA Replication Dynamics nanUNKNOWN
Investigation of the Genetic Causes of Kallmann Syndrome and Reproductive Disorders nanCOMPLETED
Molecular Genetic Epidemiology of Three Cardiac Defects -SCOR in Pediatric Cardiovascular Disease nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a CHD8 binder may also engage these)

ProteinNameSimilarity
Q09XV5 1.000 Q09XV5 →
Q9JIX5 1.000 Q9JIX5 →
B5DE69 0.999 B5DE69 →
B0R0I6 0.995 B0R0I6 →
Q58NQ4 0.992 Q58NQ4 →
Q99PM1 0.992 Q99PM1 →
F1MH24 0.991 F1MH24 →
Q80TZ9 0.991 Q80TZ9 →
Q9H334 0.991 Q9H334 →
NFRKB Nuclear factor related to kappa-B-binding protein 0.991 landscape →
Q6DJL0 0.991 Q6DJL0 →
Q0P5K4 0.991 Q0P5K4 →
Q7ZX03 0.990 Q7ZX03 →
AAK1 AP2-associated protein kinase 1 0.990 landscape →
P0CF24 0.990 P0CF24 →
P23899 0.990 P23899 →
Q5QL03 0.990 Q5QL03 →
Q1LZH5 0.990 Q1LZH5 →
SMARCA2 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 0.990 landscape →
P0C1X8 0.990 P0C1X8 →
Q62901 0.989 Q62901 →
Q9ULH7 0.989 Q9ULH7 →
Q3UHJ0 0.989 Q3UHJ0 →
Q2EJA0 0.989 Q2EJA0 →
Q4VYS1 0.989 Q4VYS1 →
Q15329 0.989 Q15329 →
Q8MJ98 0.989 Q8MJ98 →
Q5RCU4 0.989 Q5RCU4 →
P35711 0.989 P35711 →
Q498D1 0.989 Q498D1 →