COPA

Coatomer subunit alpha · P53621 · COPA on Sugi Atlas →

0 patent compounds predicted against COPA, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to COPA by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Safety and Efficacy of AAV9/AP4B1 (BFB-101) For Patients With AP4B1-related Hereditary Spastic Paraplegia Type 47 (SPG47) PHASE1/PHASE2NOT_YET_RECRUITING
Melpida: Recombinant Adeno-associated Virus (serotype 9) Encoding a Codon Optimized Human AP4M1 Transgene (hAP4M1opt) PHASE1/PHASE2RECRUITING
Ambroxol Therapy for Patients With Type 1 Gaucher Disease and Suboptimal Response to Enzyme Replacement Therapy PHASE2COMPLETED
Targeting Endoplasmic Reticulum Stress in Human Hypertension PHASE1/PHASE2RECRUITING
Copper Histidine Therapy for Menkes Diseases PHASE1/PHASE2COMPLETED
PBA Use for Treatment of ATF6-/- Patients EARLY_PHASE1SUSPENDED
Autophagy in Systemic Lupus Erythematosus nanUNKNOWN
Classification, Functional Stratification and Biomarkers in Ciliopathy (CILLICORIRCM) nanCOMPLETED
Genetics of Endocrine Tumours - Familial Isolated Pituitary Adenoma - FIPA nanRECRUITING
Genetic Analysis of Gray Platelet Syndrome nanCOMPLETED
Study of Constitutional Platelet Disease nanUNKNOWN
Phenotype/Genotype Correlations in Neuromuscular Disorders nanCOMPLETED
Muscle Tissue Bank for Muscular Dystrophy nanCOMPLETED
Genetic Investigations in Children With Developmental and Epileptic Encephalopathies in Ho Chi Minh City, Vietnam nanUNKNOWN
Biomarker Research in Inherited Movement Disorders nanRECRUITING
Non Motor Symptoms in Glucocerebrosidase-related Parkinson's Disease nanENROLLING_BY_INVITATION
Signs and Symptoms of Genetic Abnormalities Linked to Inherited Heart Disease nanCOMPLETED
Study of a Candidate Gene Involved in Goldenhar Syndrome. nanCOMPLETED
Implementation of Molecular Diagnostic Pathways nanUNKNOWN
Natural History Evaluation of Charcot Marie Tooth Disease (CMT) Types CMT1B, CMT2A, CMT4A, CMT4C, and Others nanRECRUITING
Regulation of Lymphocyte Anti-tumor Response in Metastatic Patients Treated With the mTOR Inhibitor Everolimus nanCOMPLETED
Clinical Characterization on PDE6A-related Retinitis Pigmentosa in Preparation to a Gene Therapy Trial nanCOMPLETED
Defining the Genetic Etiology of Alzheimer's Disease in the Faroe Islands nanUNKNOWN
Identifying Genes and Mutations Underlying Retinitis Pigmentosa and Allied Diseases nanUNKNOWN
Investigation of the Genetic Causes of Kallmann Syndrome and Reproductive Disorders nanCOMPLETED
Quantification of GADD34 Expression in RA nanCOMPLETED
A Multicentric European Study to Promote Clinical Trial Readiness for STXBP1-related Disorders nanRECRUITING
Gene Analysis of Parkinson's Disease nanCOMPLETED
Inherited Reproductive Disorders nanRECRUITING
MEHMO Natural History and Biomarkers nanRECRUITING

Related proteins — ESM-2 sequence neighbours (a COPA binder may also engage these)

ProteinNameSimilarity
Q8CIE6 1.000 Q8CIE6 →
Q9AUR7 1.000 Q9AUR7 →
Q27954 1.000 Q27954 →
Q0J3D9 1.000 Q0J3D9 →
Q9AUR8 1.000 Q9AUR8 →
Q96WV5 0.997 Q96WV5 →
P53622 0.997 P53622 →
Q94A40 0.997 Q94A40 →
Q9SJT9 0.995 Q9SJT9 →
Q09589 0.994 Q09589 →
O74925 0.993 O74925 →
Q19954 0.992 Q19954 →
A5DNK9 0.992 A5DNK9 →
Q09600 0.992 Q09600 →
Q24314 0.992 Q24314 →
Q6CN23 0.992 Q6CN23 →
O45487 0.991 O45487 →
Q22830 0.991 Q22830 →
P0DOB8 0.990 P0DOB8 →
Q75AQ4 0.990 Q75AQ4 →
Q21037 0.990 Q21037 →
Q8W4D0 0.990 Q8W4D0 →
Q09373 0.990 Q09373 →
Q9VV73 0.990 Q9VV73 →
Q24592 0.989 Q24592 →
P53015 0.989 P53015 →
Q22006 0.989 Q22006 →
Q55FR9 0.989 Q55FR9 →
Q9TXI7 0.989 Q9TXI7 →
Q652L2 0.989 Q652L2 →