COPB1

Coatomer subunit beta · P53618 · COPB1 on Sugi Atlas →

0 patent compounds predicted against COPB1, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to COPB1 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Hydroxychloroquine and Ivermectin for the Treatment of COVID-19 Infection PHASE3COMPLETED
Safety and Efficacy of AAV9/AP4B1 (BFB-101) For Patients With AP4B1-related Hereditary Spastic Paraplegia Type 47 (SPG47) PHASE1/PHASE2NOT_YET_RECRUITING
Melpida: Recombinant Adeno-associated Virus (serotype 9) Encoding a Codon Optimized Human AP4M1 Transgene (hAP4M1opt) PHASE1/PHASE2RECRUITING
Ambroxol Therapy for Patients With Type 1 Gaucher Disease and Suboptimal Response to Enzyme Replacement Therapy PHASE2COMPLETED
Study of Gene Therapy Using a Lentiviral Vector to Treat X-linked Chronic Granulomatous Disease PHASE1/PHASE2COMPLETED
Targeting Endoplasmic Reticulum Stress in Human Hypertension PHASE1/PHASE2RECRUITING
Phase 1b Safety Study of IMSB301 in Type 1 Interferonopathies PHASE1RECRUITING
PBA Use for Treatment of ATF6-/- Patients EARLY_PHASE1SUSPENDED
Autophagy in Systemic Lupus Erythematosus nanUNKNOWN
Classification, Functional Stratification and Biomarkers in Ciliopathy (CILLICORIRCM) nanCOMPLETED
Genetic Analysis of Gray Platelet Syndrome nanCOMPLETED
Phenotype/Genotype Correlations in Neuromuscular Disorders nanCOMPLETED
Genetic Investigations in Children With Developmental and Epileptic Encephalopathies in Ho Chi Minh City, Vietnam nanUNKNOWN
Implementation of Molecular Diagnostic Pathways nanUNKNOWN
Muscle Tissue Bank for Muscular Dystrophy nanCOMPLETED
Signs and Symptoms of Genetic Abnormalities Linked to Inherited Heart Disease nanCOMPLETED
Neurocognition in Congenital Central Hypoventilation Syndrome (CCHS) nanRECRUITING
Identifying Genes and Mutations Underlying Retinitis Pigmentosa and Allied Diseases nanUNKNOWN
Natural History Evaluation of Charcot Marie Tooth Disease (CMT) Types CMT1B, CMT2A, CMT4A, CMT4C, and Others nanRECRUITING
Biomarker Research in Inherited Movement Disorders nanRECRUITING
Investigation of the Genetic Causes of Kallmann Syndrome and Reproductive Disorders nanCOMPLETED
Establishment of Human Cellular Disease Models for Wilson Disease nanCOMPLETED
Presymptomatic Neuromuscular Junction Defects and Compensatory Mechanisms in ALS nanUNKNOWN
Genetics of Endocrine Tumours - Familial Isolated Pituitary Adenoma - FIPA nanRECRUITING
Clinical Characterization on PDE6A-related Retinitis Pigmentosa in Preparation to a Gene Therapy Trial nanCOMPLETED
Defining the Genetic Etiology of Alzheimer's Disease in the Faroe Islands nanUNKNOWN
Study of Constitutional Platelet Disease nanUNKNOWN
Pathogenesis of Primary Ciliary Dyskinesia (PCD) Lung Disease nanRECRUITING
Quantification of GADD34 Expression in RA nanCOMPLETED
A Multicentric European Study to Promote Clinical Trial Readiness for STXBP1-related Disorders nanRECRUITING

Related proteins — ESM-2 sequence neighbours (a COPB1 binder may also engage these)

ProteinNameSimilarity
Q5ZIA5 1.000 Q5ZIA5 →
A0JN39 1.000 A0JN39 →
D2SW95 1.000 D2SW95 →
Q5R922 1.000 Q5R922 →
Q9JIF7 1.000 Q9JIF7 →
P23514 1.000 P23514 →
Q66HV4 0.997 Q66HV4 →
Q9SV21 0.994 Q9SV21 →
Q9SV20 0.993 Q9SV20 →
Q53PC7 0.988 Q53PC7 →
Q0JNK5 0.988 Q0JNK5 →
Q7QG73 0.987 Q7QG73 →
Q29N38 0.977 Q29N38 →
P91926 0.976 P91926 →
Q8K2G4 0.974 Q8K2G4 →
Q9C827 0.973 Q9C827 →
Q9HBG6 0.973 Q9HBG6 →
Q8IWZ6 0.972 Q8IWZ6 →
Q9CAA0 0.972 Q9CAA0 →
Q80UM3 0.972 Q80UM3 →
Q6H8D6 0.972 Q6H8D6 →
Q3B8M3 0.971 Q3B8M3 →
P17426 0.971 P17426 →
Q8BWQ6 0.971 Q8BWQ6 →
Q5VQ78 0.970 Q5VQ78 →
Q3UGF1 0.970 Q3UGF1 →
NAA15 N-alpha-acetyltransferase 15, NatA auxiliary subunit 0.970 landscape →
Q5R4J9 0.970 Q5R4J9 →
Q5RBI3 0.969 Q5RBI3 →
Q5ZLA5 0.969 Q5ZLA5 →