COPS3

COP9 signalosome complex subunit 3 · Q9UNS2 · COPS3 on Sugi Atlas →

0 patent compounds predicted against COPS3, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to COPS3 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Treatment With HMG-COA Reductase Inhibitor of Growth and Bone Abnormalities in Children With Noonan Syndrome PHASE3COMPLETED
Melpida: Recombinant Adeno-associated Virus (serotype 9) Encoding a Codon Optimized Human AP4M1 Transgene (hAP4M1opt) PHASE1/PHASE2RECRUITING
A Study to Test How Well BI 3000202 is Tolerated by People With Type 1 Interferonopathies PHASE1ACTIVE_NOT_RECRUITING
Glutamine Supplementation in People With Immune Dysregulation EARLY_PHASE1WITHDRAWN
Role of SF3B1 Mutation in Assessment of Acute and Chronic Lymphatic Leukemia nanNOT_YET_RECRUITING
Regulation of Lymphocyte Anti-tumor Response in Metastatic Patients Treated With the mTOR Inhibitor Everolimus nanCOMPLETED
Autophagy in Systemic Lupus Erythematosus nanUNKNOWN
Genetics of Endocrine Tumours - Familial Isolated Pituitary Adenoma - FIPA nanRECRUITING
Classification, Functional Stratification and Biomarkers in Ciliopathy (CILLICORIRCM) nanCOMPLETED
Implementation of Molecular Diagnostic Pathways nanUNKNOWN
Identifying Genes and Mutations Underlying Retinitis Pigmentosa and Allied Diseases nanUNKNOWN
Genetic Analysis of Gray Platelet Syndrome nanCOMPLETED
Analysis of Post-Translational Modifications of a Critical Protein Implicated in Amyotrophic Lateral Sclerosis nanCOMPLETED
Phenotype/Genotype Correlations in Neuromuscular Disorders nanCOMPLETED
Muscle Tissue Bank for Muscular Dystrophy nanCOMPLETED
Genetic Analysis of Heart Channelopathies in Brazilian Patients and Their Relatives nanUNKNOWN
Study of Constitutional Platelet Disease nanUNKNOWN
Characterization of New Candidate Genes in Cases of Human Inherited Thrombocytopenia (CATCH) nanCOMPLETED
MERC Proteins in Saliva and GCF in Periodontal Disease (ELISA Study) nanCOMPLETED
Inherited Reproductive Disorders nanRECRUITING
Genetic Analysis of Hereditary Disorders of Hearing and Balance nanCOMPLETED
Genetic Investigation of Cancer Predisposition nanNOT_YET_RECRUITING
Family Blood Pressure Program - SAPPHIRe Network nanCOMPLETED
Family Blood Pressure Program - GENOA nanCOMPLETED
The 3q29 Deletion and 3q29 Duplication: Architecture of Behavioral Phenotypes nanRECRUITING
Identification of New FTLD Genes nanUNKNOWN
Genetics of Familial and Sporadic ALS nanCOMPLETED
MEHMO Natural History and Biomarkers nanRECRUITING
Identification of Genetic Basis of Atrioventricular Conduction Defects: From Congenital Forms to Degenerative Forms nanUNKNOWN
Study of The Association of Mutations in The NPHS2 Gene and Nephrotic Syndrome in Children and Adults in Middle East nanUNKNOWN

Related proteins — ESM-2 sequence neighbours (a COPS3 binder may also engage these)

ProteinNameSimilarity
A6H7B5 1.000 A6H7B5 →
Q5RFS2 1.000 Q5RFS2 →
Q4R898 1.000 Q4R898 →
O88543 1.000 O88543 →
Q5ZJF1 1.000 Q5ZJF1 →
Q28IV6 1.000 Q28IV6 →
Q7ZTN8 1.000 Q7ZTN8 →
Q8SYG2 1.000 Q8SYG2 →
Q68FW9 1.000 Q68FW9 →
Q5U3P0 1.000 Q5U3P0 →
PCID2 PCI domain-containing protein 2 1.000 landscape →
Q6P2U9 0.998 Q6P2U9 →
B3MCZ5 0.995 B3MCZ5 →
Q9VTL1 0.995 Q9VTL1 →
Q8W575 0.994 Q8W575 →
Q8BFV2 0.993 Q8BFV2 →
B4N3B0 0.993 B4N3B0 →
Q1HPS4 0.993 Q1HPS4 →
Q5FWP8 0.993 Q5FWP8 →
B4I7U3 0.992 B4I7U3 →
B4P8V1 0.992 B4P8V1 →
Q20585 0.992 Q20585 →
B4IWN1 0.992 B4IWN1 →
B4QFD2 0.992 B4QFD2 →
Q84K16 0.992 Q84K16 →
Q54NQ0 0.991 Q54NQ0 →
B0WTN3 0.991 B0WTN3 →
Q7QGK4 0.991 Q7QGK4 →
Q2TBN6 0.991 Q2TBN6 →
Q6INC1 0.991 Q6INC1 →