COX14 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

	Compound	Confidence	Supporting neighbours

Clinical trials — most relevant to COX14 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Impact if Desflurane Preconditioning on the Content of the Phospho-GSK-3b in the Rat's Neurons in the Model of I/R	PHASE4	WITHDRAWN
Clinical Evaluation of the Effect of Metformin in Sepsis	PHASE3	UNKNOWN
A Study of Bezafibrate in Mitochondrial Myopathy	PHASE2	COMPLETED
Deoxynucleosides Pyrimidines as Treatment for Mitochondrial Depletion Syndrome	PHASE2	RECRUITING
Study of Gene Therapy Using a Lentiviral Vector to Treat X-linked Chronic Granulomatous Disease	PHASE1/PHASE2	COMPLETED
Does Clinical Treatment of Mitochondrial Dysfunction Impact Autism Spectrum Disorder (ASD)?	PHASE1	UNKNOWN
Mitochondrial Function of Immune Cells in Sepsis	nan	COMPLETED
Effect of Subtle Energy Transmission and Tao Calligraphy Mindfulness Practice on Mitochondrial DNA in Peripheral Blood Leukocytes	nan	NOT_YET_RECRUITING
Abnormalities in the Effects of Insulin and Exercise on Glucose- and Lipid Metabolism in Obesity and Type 2 Diabetes	nan	COMPLETED
Plasma Cytochrome c as Biomarker of Traumatic Injury and Predictor of Outcome	nan	COMPLETED
Genomic Profiling of Mitochondrial Disease - Imaging Analysis for Precise Mitochondrial Medicine	nan	COMPLETED
Relationship Between Mitochondrial Dysfunction and Fatique in Cancer Patients Following External Beam Radiation Therapy	nan	COMPLETED
Reactive Oxygen Species Following Aortic Valve Replacement	nan	COMPLETED
Tissue Sample Study for Mitochondrial Disorders	nan	ENROLLING_BY_INVITATION
The Crosstalk Between the Epigenome and Mitochondria in SCI	nan	NOT_YET_RECRUITING
Mitoferrin-1 Expression in Erythropoietic Protoporphyria (Porphyria Rare Disease Clinical Research Consortium (RDCRC))	nan	COMPLETED
Effect of Branched Chain Amino Acids on Muscle	nan	COMPLETED
Identification of Large-Scale Mutations of POLG Gene by QMPSF in Patients With Mitochondrial DNA Instability.	nan	UNKNOWN
The Genetics of Diabetes in Southern California Chinese Americans	nan	WITHDRAWN
Biologic Mechanisms for Pain Variation After Physical Activity in Osteoarthritis	nan	COMPLETED
Measuring Protein Turnover in Humans Across the Lifespan by Metabolic Labeling With Deuterium Oxide	nan	RECRUITING
Hyperbaric Oxygen Therapy for Post Traumatic Stress Disorder	nan	COMPLETED
North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC)	nan	RECRUITING
Effect of Dietary Nitrate on Immobilization-induced Changes in Skeletal Muscle in Young Healthy Men	nan	RECRUITING
Use of GDF15 as a Biomarker for Early Diagnosis of DM and Monitoring of Progress of Complications in Asians	nan	UNKNOWN
Drug Repurposing for Mitochondrial Disorders Using iPSCs Derived Neural Cells	nan	RECRUITING
DNA QUANTIFICATION TECHNIQUE AS A INTERPRETATION TOOL IN MITOCHONDRIAL DISEASES	nan	COMPLETED
Collection of Blood and Skin Samples From Patients With Primary Mitochondrial Diseases and Healthy Volunteers	nan	RECRUITING
Molecular Profile of the Evolution of Inclusion Body Myositis	nan	COMPLETED
Gastrointestinal Dysfunction in Children Affected With Mitochondrial Disorders	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a COX14 binder may also engage these)

Protein	Name	Similarity
Q1RMH3	—	1.000	Q1RMH3 →
Q5XFV8	—	0.998	Q5XFV8 →
Q8BH51	—	0.997	Q8BH51 →
A8E7D3	—	0.990	A8E7D3 →
Q7YRK2	—	0.973	Q7YRK2 →
Q63ZZ0	—	0.973	Q63ZZ0 →
Q5R987	—	0.972	Q5R987 →
Q8VCR3	—	0.971	Q8VCR3 →
B7Z0X7	—	0.971	B7Z0X7 →
Q7YRK1	—	0.971	Q7YRK1 →
A8MTT3	—	0.970	A8MTT3 →
Q8BTC1	—	0.970	Q8BTC1 →
P14790	—	0.970	P14790 →
Q9NWH2	—	0.970	Q9NWH2 →
P56378	—	0.969	P56378 →
Q8BTE5	—	0.969	Q8BTE5 →
Q78IK2	—	0.968	Q78IK2 →
Q7YRJ9	—	0.968	Q7YRJ9 →
Q9CPQ1	—	0.968	Q9CPQ1 →
P56379	—	0.968	P56379 →
C0HLN0	—	0.968	C0HLN0 →
P11951	—	0.967	P11951 →
Q0Q4Z0	—	0.967	Q0Q4Z0 →
P0DO45	—	0.967	P0DO45 →
Q4V8S3	—	0.967	Q4V8S3 →
P04038	—	0.967	P04038 →
Q3ZBI7	—	0.967	Q3ZBI7 →
Q02921	—	0.967	Q02921 →
ATP5MK	ATP synthase F(0) complex subunit k, mitochondrial	0.967	landscape →
P80977	—	0.967	P80977 →