COX5A

Cytochrome c oxidase subunit 5A, mitochondrial · P20674 · COX5A on Sugi Atlas →

0 patent compounds predicted against COX5A, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to COX5A by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Phase III Trial of Coenzyme Q10 in Mitochondrial Disease PHASE3COMPLETED
Clinical Evaluation of the Effect of Metformin in Sepsis PHASE3UNKNOWN
A Study of the Efficacy and Safety of MT1621 in Thymidine Kinase 2 (TK2) Deficiency (Treatment naïve) PHASE3WITHDRAWN
Mitochondrial Dysfunction in the Pathophysiology and Treatment of Bipolar Disorder PHASE2WITHDRAWN
A Study of Bezafibrate in Mitochondrial Myopathy PHASE2COMPLETED
Relative Mitochondrial Toxicity of Tenofovir Alafenamide (TAF) vs. Tenofovir Disoproxil Fumarate (TDF) PHASE1/PHASE2COMPLETED
Does Clinical Treatment of Mitochondrial Dysfunction Impact Autism Spectrum Disorder (ASD)? PHASE1UNKNOWN
Plasma Cytochrome c as Biomarker of Traumatic Injury and Predictor of Outcome nanCOMPLETED
The Crosstalk Between the Epigenome and Mitochondria in SCI nanNOT_YET_RECRUITING
Tissue Sample Study for Mitochondrial Disorders nanENROLLING_BY_INVITATION
Abnormalities in the Effects of Insulin and Exercise on Glucose- and Lipid Metabolism in Obesity and Type 2 Diabetes nanCOMPLETED
Mitoquines in COPD nanUNKNOWN
Reactive Oxygen Species Following Aortic Valve Replacement nanCOMPLETED
Genomic Profiling of Mitochondrial Disease - Imaging Analysis for Precise Mitochondrial Medicine nanCOMPLETED
The Genetics of Diabetes in Southern California Chinese Americans nanWITHDRAWN
Cardiac Mitochondrial Function in Explanted Human Hearts nanUNKNOWN
Identification of Large-Scale Mutations of POLG Gene by QMPSF in Patients With Mitochondrial DNA Instability. nanUNKNOWN
Relationship Between Mitochondrial Dysfunction and Fatique in Cancer Patients Following External Beam Radiation Therapy nanCOMPLETED
Mitochondrial Function of Immune Cells in Sepsis nanCOMPLETED
Ultrastructural Characteristics of Mitochondria in Cardiomyocytes in Heart Failure nanRECRUITING
North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC) nanRECRUITING
Effect of Subtle Energy Transmission and Tao Calligraphy Mindfulness Practice on Mitochondrial DNA in Peripheral Blood Leukocytes nanNOT_YET_RECRUITING
The Natural History of Mitochondrial Diseases nanRECRUITING
Natural History in Primary Mitochondrial Myopathies nanRECRUITING
Collection of Blood and Skin Samples From Patients With Primary Mitochondrial Diseases and Healthy Volunteers nanRECRUITING
Effects of Acute Energy Deficit and Aerobic Exercise on Muscle Quality nanCOMPLETED
Assessing the Role of Mitochondrial Dysfunction in Primary Progressive Multiple Sclerosis nanUNKNOWN
The Fuel and Rhythm (FAR) Phase 2 Study nanCOMPLETED
Biologic Mechanisms for Pain Variation After Physical Activity in Osteoarthritis nanCOMPLETED
Gastrointestinal Dysfunction in Children Affected With Mitochondrial Disorders nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a COX5A binder may also engage these)

ProteinNameSimilarity
B0VYX8 1.000 B0VYX8 →
B0VYX6 1.000 B0VYX6 →
B0VYX7 1.000 B0VYX7 →
B0VYX1 1.000 B0VYX1 →
B0VYY2 1.000 B0VYY2 →
B0VYX3 1.000 B0VYX3 →
B0VYX4 1.000 B0VYX4 →
B0VYY3 1.000 B0VYY3 →
Q53CF8 1.000 Q53CF8 →
B0VYX5 1.000 B0VYX5 →
B0VYX9 1.000 B0VYX9 →
B0VYY0 1.000 B0VYY0 →
Q53CG1 1.000 Q53CG1 →
B0VYY1 1.000 B0VYY1 →
B0VYX2 1.000 B0VYX2 →
Q94514 1.000 Q94514 →
P12787 1.000 P12787 →
B0VYY4 1.000 B0VYY4 →
P00426 0.998 P00426 →
P11240 0.998 P11240 →
B0VYY5 0.997 B0VYY5 →
Q9UTF6 0.992 Q9UTF6 →
B3MI37 0.989 B3MI37 →
B4LKE5 0.989 B4LKE5 →
B3N6D9 0.989 B3N6D9 →
P55954 0.988 P55954 →
B4NXN5 0.987 B4NXN5 →
O93980 0.987 O93980 →
A1Z897 0.987 A1Z897 →
O94373 0.987 O94373 →