CS

Citrate synthase, mitochondrial · O75390 · CS on Sugi Atlas →

0 patent compounds predicted against CS, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to CS by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Effect of Vitamin D Supplementation on Exercise Adaptations in Patients on Statin Therapy PHASE3COMPLETED
Chronic Versus Acute Dosing of Sodium Citrate for Swimming 200m PHASE3COMPLETED
Clinical Evaluation of the Effect of Metformin in Sepsis PHASE3UNKNOWN
Acetylcarnitine and Insulin Sensitivity PHASE2COMPLETED
A Study of Bezafibrate in Mitochondrial Myopathy PHASE2COMPLETED
Effect of a Wide Spectrum Nutritional Supplement on Mitochondrial Function in Children With Autism Spectrum Disorder PHASE2COMPLETED
Metabolic Cofactor Supplementation in Alzheimer's Disease (AD) and Parkinson's Disease (PD) Patients PHASE2COMPLETED
Effect of Subtle Energy Transmission and Tao Calligraphy Mindfulness Practice on Mitochondrial DNA in Peripheral Blood Leukocytes nanNOT_YET_RECRUITING
Skeletal Muscle Mitochondrial Abnormalities and the Metabolic Syndrome in PAH nanCOMPLETED
Lifestyle Intervention in Preparation for Pregnancy (LIPP) nanCOMPLETED
Triheptanoin (UX007) to Treat Citrate Transporter Deficiency nanNO_LONGER_AVAILABLE
Exercise, Statins, and the Metabolic Syndrome nanCOMPLETED
Mitochondrial Methylation in Type 2 Diabetes nanCOMPLETED
Multi-omics Study in Citrin Deficiency nanACTIVE_NOT_RECRUITING
Abnormalities in the Effects of Insulin and Exercise on Glucose- and Lipid Metabolism in Obesity and Type 2 Diabetes nanCOMPLETED
Nicotinamide Levels in Serum, Aqueous Humor, and Tear Film in Glaucoma and Correlations With Mitochondrial Damage-Associated Molecular Patterns (mtDAMPs) and Senescence-Associated Secretory Phenotype (SASP) nanNOT_YET_RECRUITING
Mitoquines in COPD nanUNKNOWN
DYNamic Assessment of Multi Organ Level Dysfunction in Patients Recovering From Covid-19 nanCOMPLETED
Mitochondrial Energy Metabolism in Obese Women nanCOMPLETED
Glycine and Magnesium+Thiamine for the Treatment of Primary Ciliary Dyskinesia nanRECRUITING
Development of Novel Therapies for NIDDM nanCOMPLETED
Chronic Kidney Disease and Heart Failure With Preserved Ejection Fraction: The Role of Mitochondrial Dysfunction nanCOMPLETED
Effect of Acute Fructose Load in Human nanCOMPLETED
Pilot Study of Mitochondrial Biology in Human Platelets nanCOMPLETED
Clinical Study of Hydroxytyrosol (HT) in Mitochondrial Diseases nanCOMPLETED
GDF-15 as a Biomarker for Mitochondrial Disease nanCOMPLETED
McArdle Disease Treatment by Ketogenic Diet nanCOMPLETED
Effect of Exercise Training on Protein Expression in Skeletal Muscle Tissue After Exercise in Peripheral Arterial Disease nanCOMPLETED
Mitochondria and Metabolic Syndrome in a Southern California Chinese Cohort nanCOMPLETED
Impact of Iron Deficiency and Its Correction on Mitochondrial Metabolism of the Cardiomyocyte (MitoCardioFer) nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a CS binder may also engage these)

ProteinNameSimilarity
P0C1Z2 1.000 P0C1Z2 →
Q8VHF5 1.000 Q8VHF5 →
Q7ZVY5 1.000 Q7ZVY5 →
P51044 1.000 P51044 →
Q0QHL3 1.000 Q0QHL3 →
Q17GM7 1.000 Q17GM7 →
Q9W401 1.000 Q9W401 →
Q0GNE0 1.000 Q0GNE0 →
Q6S9V5 1.000 Q6S9V5 →
Q6S9V7 1.000 Q6S9V7 →
B0YD89 1.000 B0YD89 →
Q16P20 1.000 Q16P20 →
Q10306 1.000 Q10306 →
Q6C793 1.000 Q6C793 →
Q29RK1 1.000 Q29RK1 →
Q61JF9 1.000 Q61JF9 →
Q28DK1 1.000 Q28DK1 →
Q6S9V8 1.000 Q6S9V8 →
P34085 1.000 P34085 →
P00889 1.000 P00889 →
P49298 1.000 P49298 →
Q4S5X1 1.000 Q4S5X1 →
Q7ZWZ5 1.000 Q7ZWZ5 →
Q9CZU6 1.000 Q9CZU6 →
P00890 1.000 P00890 →
C7C435 1.000 C7C435 →
Q6S9V6 1.000 Q6S9V6 →
O80433 1.000 O80433 →
Q0GNE1 1.000 Q0GNE1 →
P20115 1.000 P20115 →