DDX6 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
Azd-6482 (SCHEMBL825695)	1.00	1/20
Azd-6482 (SCHEMBL1812377)	1.00	1/20
Azd-6482 (SCHEMBL4353531)	1.00	1/20
SCHEMBL26137372	0.85	1/20
SCHEMBL26137495	0.85	1/20
SCHEMBL909768	0.84	1/20
SCHEMBL4348187	0.84	1/20
SCHEMBL4348197	0.84	1/20
SCHEMBL25359198	0.84	1/20
SCHEMBL25952290	0.84	1/20
SCHEMBL27116153	0.84	1/20
SCHEMBL26136961	0.81	1/20
SCHEMBL26136962	0.81	1/20
SCHEMBL27116441	0.81	1/20
SCHEMBL25414825	0.80	1/20
SCHEMBL25414829	0.80	1/20
SCHEMBL25415273	0.80	1/20
SCHEMBL25415277	0.80	1/20
SCHEMBL26136960	0.80	1/20
SCHEMBL26137362	0.80	1/20

Clinical trials — most relevant to DDX6 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Reverse Transcriptase Inhibitors in AGS	PHASE2	COMPLETED
Pharmacogenetics of Disulfiram for Cocaine	PHASE2	COMPLETED
Study of Individuals and Families With Aberrations in DDX41 or Similar Cancer Predisposition Variants	nan	RECRUITING
DDX3X Syndrome -The Seaver Autism Center for Research and Treatment is Characterizing DDX3X-related Neurodevelopmental Disorders Using Genetic, Medical, and Neuropsychological Measures.	nan	COMPLETED
Better Delineation of DDX3X Related Phenotype and Epigenetic Signature.	nan	UNKNOWN
Exome Analysis in Hearing Impaired Patients	nan	UNKNOWN
Gene Mutations and Rescue in Human Congenital Diaphragmatic Hernia	nan	UNKNOWN
Whole-genome Sequencing Study in Patients With Diminished Ovarian Reserve	nan	UNKNOWN
Genetic Analysis of Hereditary Disorders of Hearing and Balance	nan	COMPLETED
Screening for Early Pancreatic Neoplasia (Cancer of the Pancreas Screening or CAPS4 Study)	nan	COMPLETED
Registry and Natural History Study for Early Onset Hereditary Spastic Paraplegia	nan	RECRUITING
Result Of Karyotyping in Pediatric Patients With Congenital Anomalies and Developmental Delay	nan	NOT_YET_RECRUITING
DICER1-related Pleuropulmonary Blastoma Cancer Predisposition Syndrome: A Natural History Study	nan	RECRUITING
The Genetic Study of Primary Angle-Closure Glaucoma	nan	UNKNOWN
Germline Mutations in Pancreatic Adenocarcinoma	nan	COMPLETED
PCD New Gene Discovery	nan	COMPLETED
Whole Genome Scan of Extended Families With Familial Vocal Cord Paralysis	nan	COMPLETED
Secretin-Stimulated Magnetic Resonance Cholangiopancreatography (S-MRCP) in Pancreatic Patients	nan	COMPLETED
Genetic Analysis of Heart Channelopathies in Brazilian Patients and Their Relatives	nan	UNKNOWN
A Study Providing Genetic Testing to Find Those Who May Have Primary Ciliary Dyskinesia for Potential Clinical Trials	nan	ACTIVE_NOT_RECRUITING
Prospective Study to Assess Medical Performance of Optical Mapping and Long Read Sequencing in Detecting Numerical and Structural Chromosome Abnormalities	nan	COMPLETED
Whole Exome and Whole Genome Sequencing for Genotyping of Inherited and Congenital Eye Conditions	nan	RECRUITING
Shwachman Diamond Syndrome Registry and Study	nan	RECRUITING
Genetics of Primary Ciliary Dyskinesia	nan	COMPLETED
Diagnostic Research in Patients With Rare Diseases - Solving the Unsolved Rare Diseases	nan	UNKNOWN
Genetic Testing in Detection of Late-Onset Hearing Loss	nan	COMPLETED
Clinical and Genetic Analysis in Congenital Hypothyroidism Due to Thyroid Dysgenesis.	nan	COMPLETED
Cause of Familial Testicular Cancer	nan	COMPLETED
Diaphragmatic Hernia Research & Exploration, Advancing Molecular Science	nan	RECRUITING
A Study of the Genetic Analysis of Brain Disorders	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a DDX6 binder may also engage these)

Protein	Name	Similarity
Q5ZKB9	—	1.000	Q5ZKB9 →
Q5RFQ5	—	1.000	Q5RFQ5 →
Q9WTM2	—	1.000	Q9WTM2 →
Q0IHV9	—	1.000	Q0IHV9 →
P54824	—	1.000	P54824 →
A7TGU7	—	0.999	A7TGU7 →
P54823	—	0.999	P54823 →
Q7XMK8	—	0.997	Q7XMK8 →
Q09181	—	0.997	Q09181 →
Q9M2E0	—	0.997	Q9M2E0 →
Q94BV4	—	0.996	Q94BV4 →
Q75BS4	—	0.996	Q75BS4 →
Q4HW67	—	0.994	Q4HW67 →
Q8RXK6	—	0.993	Q8RXK6 →
A6ZXG9	—	0.993	A6ZXG9 →
P39517	—	0.993	P39517 →
Q54TF8	—	0.993	Q54TF8 →
Q54E49	—	0.992	Q54E49 →
A3LWX3	—	0.992	A3LWX3 →
Q0U7S9	—	0.992	Q0U7S9 →
O13792	—	0.992	O13792 →
A3LNL1	—	0.992	A3LNL1 →
Q6CSZ7	—	0.991	Q6CSZ7 →
A2QY39	—	0.991	A2QY39 →
A4R715	—	0.991	A4R715 →
Q6H7S2	—	0.991	Q6H7S2 →
Q6FQU5	—	0.991	Q6FQU5 →
Q4WWD3	—	0.991	Q4WWD3 →
Q0CBE1	—	0.991	Q0CBE1 →
A1CJ18	—	0.991	A1CJ18 →