DECR1

2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing], mitochondrial · Q16698 · DECR1 on Sugi Atlas →

0 patent compounds predicted against DECR1, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to DECR1 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Effects of Statin and Ezetimibe Association on Kinetics of Artificial Chilomicrons PHASE4COMPLETED
Atorvastatin, Aspirin, Oxidative Stress, Coagulation and Platelet Activation Indexes PHASE4UNKNOWN
The Effect of Calcium and Vitamin D Supplements on Metabolic and Hormonal Disturbances in Polycystic Ovary Syndrome Patients PHASE3COMPLETED
Androgen Ablation Therapy With or Without Chemotherapy in Treating Patients With Metastatic Prostate Cancer PHASE3COMPLETED
Safety and Efficacy of Lapaquistat Acetate Taken Alone and With Atorvastatin in Subjects With Primary Dyslipidemia PHASE3COMPLETED
Smith-Lemli-Opitz Syndrome and Cholic Acid PHASE1/PHASE2COMPLETED
Toxicity and Efficacy Evaluation of Topical Minoxidil in Acne Vulgaris PHASE1/PHASE2UNKNOWN
Dose-Ranging Study for Miconazole Oil for Treatment of Otomycosis PHASE2COMPLETED
Vitamin D Intervention Trial in Healthy Chinese, Phase II PHASE1COMPLETED
Efavirenz for Patients With Alzheimer's Disease PHASE1COMPLETED
A Long-Term Study of Cholesterol Supplements for Smith-Lemli-Opitz Syndrome nanWITHDRAWN
Replacement of Vitamin D in Patients With Active Tuberculosis nanCOMPLETED
Study of Smith-Lemli-Opitz Syndrome nanCOMPLETED
Gene Polymorphisms Influencing Steroid Synthesis and Action nanWITHDRAWN
Gene Expression, Metabolomic, Microbiome, and Calcium Metabolism in Response to Varied Vitamin D Dosages nanCOMPLETED
Effect of Surgical or Conservative Approach in Patients With Adrenal Incidentalomas nanUNKNOWN
Gene Expression in Obesity and Insulin Resistance nanCOMPLETED
Mechanisms of Glucose Lowering Effect of Colesevelam HCl nanCOMPLETED
Genetic Association of Diabetic Retinopathy-1 nanUNKNOWN
Pattern of Gene Expression in Adipose Tissue From Patients With Cushing Syndrome nanCOMPLETED
EPICO: (Study for the Pro-resolution of Chronic Inflammation in Obesity. Original Acronym From Spanish) nanUNKNOWN
Steroid Treatment of Idiopathic Nephrotic Syndrome nanCOMPLETED
Fish Oil and Nonalcoholic Fatty Liver Disease (NAFLD) Study nanCOMPLETED
Influence of WNT4 VEZT FSHB and SIRT1 SNPs in Endometriosis: a Case Control Study of the Sardinian Population nanUNKNOWN
Urinary DENND1A.V2 as a Predictor of Pubertal Hyperandrogenemia nanSUSPENDED
Genetic, Dietary and Environmental Influences on Vitamin D Metabolism nanCOMPLETED
Prenatal Screening For Smith-Lemli-Opitz Syndrome nanCOMPLETED
S0424 - Carcinogens in Lung Tissue From Smokers (Closed to Entry as of 7/15/07) and Non-Smokers With Newly Diagnosed Stage I, Stage II, or Stage III Non-Small Cell Lung Cancer nanCOMPLETED
11C-Acetate PET/CT Non-FDG-Avid Tumors nanUNKNOWN
Omics-based Predictors of NAFLD/Potential NASH nanUNKNOWN

Related proteins — ESM-2 sequence neighbours (a DECR1 binder may also engage these)

ProteinNameSimilarity
Q9CQ62 1.000 Q9CQ62 →
Q64591 0.998 Q64591 →
Q22230 0.994 Q22230 →
Q93761 0.991 Q93761 →
Q23116 0.989 Q23116 →
Q9WVK3 0.989 Q9WVK3 →
P32573 0.987 P32573 →
Q9BY49 0.986 Q9BY49 →
Q02207 0.986 Q02207 →
Q9LTV6 0.985 Q9LTV6 →
A0A075TRB3 0.984 A0A075TRB3 →
Q9Z2M4 0.984 Q9Z2M4 →
Q9JIF5 0.984 Q9JIF5 →
A0A1W5SR39 0.983 A0A1W5SR39 →
L0E4F8 0.983 L0E4F8 →
Q6NV34 0.982 Q6NV34 →
A0A1B2CTA9 0.982 A0A1B2CTA9 →
Q9WV68 0.981 Q9WV68 →
Q5RCH8 0.981 Q5RCH8 →
Q9FZ42 0.981 Q9FZ42 →
P27581 0.981 P27581 →
P22245 0.980 P22245 →
Q1RH28 0.980 Q1RH28 →
Q9MA93 0.980 Q9MA93 →
P22246 0.980 P22246 →
Q9VXJ0 0.979 Q9VXJ0 →
Q5RBV3 0.979 Q5RBV3 →
O24990 0.979 O24990 →
P51660 0.979 P51660 →
A1CFM1 0.979 A1CFM1 →