DERL1 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

	Compound	Confidence	Supporting neighbours

Clinical trials — most relevant to DERL1 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Cornelia De Lange Syndrome: Assessing Positive Effects of Lithium Treatment	PHASE2/PHASE3	RECRUITING
A Study of the Tolerance, Safety, and Pharmacokinetics of GNR-055 in Healthy Volunteers	PHASE1	COMPLETED
Human Leukocyte Antigen (HLA) - A*2402 Restricted Peptide Vaccine Therapy in Patients With Advanced Esophageal Cancer	PHASE1	COMPLETED
Breakpoint Analysis of de Novo Apparently Balanced Chromosomal Translocations	EARLY_PHASE1	COMPLETED
A Study on Risk Mutations of Vulnerability Genes of Schizophrenia	nan	UNKNOWN
A Patient-tailored Genetic/Biomarker/iPSC Combined Approach in ALS - PERMEALS	nan	RECRUITING
Identification of an Asthma Susceptibility Gene on 3P	nan	COMPLETED
Gait in Rare Diseases	nan	COMPLETED
Whole-genome Sequencing Study in Patients With Diminished Ovarian Reserve	nan	UNKNOWN
Diaphragmatic Hernia Research & Exploration, Advancing Molecular Science	nan	RECRUITING
Chromosome 5Q Gene Variants and Asthma-Related Traits	nan	COMPLETED
Clinical Outcome Study for Dysferlinopathy	nan	UNKNOWN
Behavioral Assessment and Treatment of Problem Behavior in Children With Cornelia de Lange Syndrome	nan	RECRUITING
Gene Mutations and Rescue in Human Congenital Diaphragmatic Hernia	nan	UNKNOWN
Positional Cloning of the Gene(s) Responsible for Alagille Syndrome	nan	COMPLETED
Genetic Basis of Non Syndromic Congenital Diaphragmatic Hernia	nan	COMPLETED
Speech and Short-term Memory Functions in Dyslexia: a Combined MEG and EEG Study	nan	UNKNOWN
Registry and Natural History of Epilepsy-Dyskinesia Syndromes	nan	RECRUITING
Genetics of Primary Ciliary Dyskinesia	nan	COMPLETED
Allergy and Immunology Natural History Study	nan	RECRUITING
Implementation of Molecular Diagnostic Pathways	nan	UNKNOWN
Impact of Seasonal Malaria Chemoprevention on Immunity Against Malaria Among Children in Northern Benin	nan	COMPLETED
Genetics and Psychopathology in the 22q11 Deletion Syndrome	nan	UNKNOWN
Genetic Characterization of Parkinson's Disease	nan	COMPLETED
Depressed AIRE Gene Expression Causes Immune Cell Dysfunction & Autoimmunity in Down Syndrome	nan	COMPLETED
Universal Rare Gene Study: A Registry and Natural History Study of Retinal Dystrophies Associated With Rare Disease-Causing Genetic Variants	nan	RECRUITING
Transcranial Magnetic Stimulation (TMS) Studies of Dystonia	nan	COMPLETED
PCD New Gene Discovery	nan	COMPLETED
Study of the Value of Trio Exome Sequencing in the Etiological Assessment of Specific Non-syndromic Language and Learning Disorders	nan	RECRUITING
Precision Diagnosis and Therapy for Rare Diseases by Interpreting Non-coding Genomes	nan	RECRUITING

Related proteins — ESM-2 sequence neighbours (a DERL1 binder may also engage these)

Protein	Name	Similarity
Q71SS4	—	1.000	Q71SS4 →
Q5R9W3	—	1.000	Q5R9W3 →
Q99J56	—	1.000	Q99J56 →
Q93561	—	0.998	Q93561 →
Q54IC9	—	0.997	Q54IC9 →
Q851X7	—	0.996	Q851X7 →
Q9VQ57	—	0.995	Q9VQ57 →
Q8VZ96	—	0.995	Q8VZ96 →
Q4G2J3	—	0.995	Q4G2J3 →
Q4G2J5	—	0.994	Q4G2J5 →
Q21997	—	0.994	Q21997 →
Q4G2J6	—	0.994	Q4G2J6 →
Q5RC74	—	0.993	Q5RC74 →
Q54NN1	—	0.992	Q54NN1 →
Q8BNI4	—	0.992	Q8BNI4 →
Q9GZP9	—	0.992	Q9GZP9 →
Q06397	—	0.992	Q06397 →
Q8VZU9	—	0.991	Q8VZU9 →
Q9ZS88	—	0.991	Q9ZS88 →
Q96Q80	—	0.990	Q96Q80 →
Q4G2J4	—	0.989	Q4G2J4 →
Q0P5E4	—	0.988	Q0P5E4 →
Q12743	—	0.985	Q12743 →
Q9D8K3	—	0.984	Q9D8K3 →
Q9Y7Y0	—	0.980	Q9Y7Y0 →
Q9LET3	—	0.979	Q9LET3 →
P38307	—	0.979	P38307 →
O94458	—	0.978	O94458 →
B0Y4Q8	—	0.978	B0Y4Q8 →
A2Q9P5	—	0.977	A2Q9P5 →