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DRG1

Developmentally-regulated GTP-binding protein 1 · Q9Y295 · DRG1 on Sugi Atlas →

703 patent compounds predicted against DRG1, 395 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL24278189 SCHEMBL24278189 0.84 1/20
SCHEMBL24278046 SCHEMBL24278046 0.81 1/20
SCHEMBL24278190 SCHEMBL24278190 0.81 1/20
SCHEMBL24277995 SCHEMBL24277995 0.80 1/20
SCHEMBL29474403 SCHEMBL29474403 0.80 1/20
SCHEMBL29474404 SCHEMBL29474404 0.80 1/20
SCHEMBL29474402 SCHEMBL29474402 0.79 1/20
SCHEMBL15602535 SCHEMBL15602535 0.77 1/20
Oxalic Acid Oxalic Acid (SCHEMBL29474399) 0.77 1/20
Oxalic Acid Oxalic Acid (SCHEMBL29474407) 0.77 1/20
SCHEMBL24278002 SCHEMBL24278002 0.76 1/20
SCHEMBL15602438 SCHEMBL15602438 0.75 1/20
Trifluoroacetic Acid Trifluoroacetic Acid (SCHEMBL29474401) 0.74 1/20
SCHEMBL15602439 SCHEMBL15602439 0.72 1/20
SCHEMBL29474408 SCHEMBL29474408 0.72 1/20
SCHEMBL31181447 SCHEMBL31181447 0.72 1/20
SCHEMBL24278041 SCHEMBL24278041 0.70 1/20
SCHEMBL19909996 SCHEMBL19909996 0.70 1/20
SCHEMBL15602556 SCHEMBL15602556 0.68 1/20
SCHEMBL15602526 SCHEMBL15602526 0.68 1/20

Clinical trials — most relevant to DRG1 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Management of Retinitis Pigmentosa Via Combination of Wharton's Jelly-derived Mesenchymal Stem Cells and Magnovision PHASE3COMPLETED
Influence of Genetics in Pain Sensitivity PHASE2COMPLETED
Peptide Vaccine Focusing on Prevention of the Recurrence for Bladder Cancer PHASE2UNKNOWN
Exploring the Genetics of Neuropathic Pain nanRECRUITING
DRG Mutations in Prostate Cancer: a Guiding Light for Enhanced Screening and Personalised Therapy nanACTIVE_NOT_RECRUITING
Protein Synthesis in the Brain of Patients With Fragile X Syndrome nanCOMPLETED
Changes in Skin Innervation of Neurologically Asymptomatic Type 2 Diabetic Patients: the Correlation With the Diabetic Parameters and Neurotrophins. nanUNKNOWN
Nerve Ultrasound in Acquired and Genetic Sensory Neuronopathies nanNOT_YET_RECRUITING
Pulsed Radiofrequency in Chronic Lumbosacral Radicular Pain nanCOMPLETED
Identifying Genes and Mutations Underlying Retinitis Pigmentosa and Allied Diseases nanUNKNOWN
The Relationship Between Chronic OA Pain and Cognition Deficits in OA Patients. nanCOMPLETED
Gait in Rare Diseases nanCOMPLETED
Effect of FODMAPs on Mucosal Inflammation in IBS Patients nanUNKNOWN
Pain Predict Genetics nanRECRUITING
Natural History Evaluation of Charcot Marie Tooth Disease (CMT) Types CMT1B, CMT2A, CMT4A, CMT4C, and Others nanRECRUITING
iPSC Neurons From Adult Survivors of Childhood Cancer Who Have Persistent Vincristine-Induced Neuropathy nanCOMPLETED
Genetics of Pediatric-Onset Motor Neuron and Neuromuscular Diseases nanCOMPLETED
Identification of New Genes Implicated in Rare Neurosensory Diseases by Whole Exome Sequencing nanUNKNOWN
Biomarker Research in Inherited Movement Disorders nanRECRUITING
Inherited Reproductive Disorders nanRECRUITING
Acute Pain Genomic Study nanCOMPLETED
Genetic Analysis of Hereditary Disorders of Hearing and Balance nanCOMPLETED
Diagnosis of Primary Ciliary Dyskinesia nanCOMPLETED
Genetic Characterization of Parkinson's Disease nanCOMPLETED
Investigating Phenotypic, Epigenetic, and NeuroGenetic Traits in Rare and Ultra-rare Neurodevelopmental Disorders (Project PENGUIN) nanRECRUITING
Transcriptomic Profile of Patients Treated With Different Modalities of Spinal Cord Stimulation nanUNKNOWN
Exome Evaluation in Patients Living With Diabetes Complicated by Charcot Neuroarthropathy. nanCOMPLETED
Painful Channelopathies Study nanUNKNOWN
Classification, Functional Stratification and Biomarkers in Ciliopathy (CILLICORIRCM) nanCOMPLETED
Genetic Analyses of Nonsyndromic and Syndromic Deafness in Pakistan nanENROLLING_BY_INVITATION

Related proteins — ESM-2 sequence neighbours (a DRG1 binder may also engage these)

ProteinNameSimilarity
P43690 — 1.000 P43690 →
P34280 — 1.000 P34280 →
Q54HP3 — 1.000 Q54HP3 →
Q3MHP5 — 1.000 Q3MHP5 →
Q9SVA6 — 1.000 Q9SVA6 →
Q9LQK0 — 1.000 Q9LQK0 →
P32234 — 1.000 P32234 →
P32233 — 1.000 P32233 →
Q58D56 — 1.000 Q58D56 →
P53295 — 1.000 P53295 →
P32235 — 0.999 P32235 →
P39729 — 0.997 P39729 →
P55039 — 0.996 P55039 →
Q58722 — 0.995 Q58722 →
Q54WT4 — 0.994 Q54WT4 →
Q9QXB9 — 0.993 Q9QXB9 →
Q9UT21 — 0.993 Q9UT21 →
Q8TU79 — 0.991 Q8TU79 →
Q5HXD1 — 0.990 Q5HXD1 →
Q2HJ33 — 0.990 Q2HJ33 →
A8F5A0 — 0.989 A8F5A0 →
Q9CAI1 — 0.989 Q9CAI1 →
Q9CP90 — 0.988 Q9CP90 →
Q6KZ24 — 0.988 Q6KZ24 →
Q97B28 — 0.988 Q97B28 →
A0PX78 — 0.988 A0PX78 →
P44681 — 0.987 P44681 →
A6URW3 — 0.987 A6URW3 →
OLA1 Obg-like ATPase 1 0.987 landscape →
Q0W0X9 — 0.986 Q0W0X9 →