DSG1

Desmoglein-1 · Q02413 · DSG1 on Sugi Atlas →

0 patent compounds predicted against DSG1, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to DSG1 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Effect of Dexmedetomidine and Total Intravenous Anesthesia on Endothelial Damage-Related Biomarkers PHASE4COMPLETED
Gluten Sensitivity in Non-Celiac Patients PHASE3COMPLETED
A Phase 1/2, Open-label, Safety and Dosing Study of Autologous CART Cells (Desmoglein 3 Chimeric Autoantibody Receptor T Cells [DSG3-CAART] or CD19-specific Chimeric Antigen Receptor T Cells [CABA-201]) in Subjects With Active, Pemphigus Vulgaris (RESET-PV) PHASE1/PHASE2RECRUITING
Rituximab in the Treatment of Patients With Bullous Pemphigoid PHASE1/PHASE2COMPLETED
Anti-IL-5 Therapy in Bullous Pemphigoid (BP) PHASE2COMPLETED
Can E-cadherin Found in Tissue/Blood be Valuable in Identifying & Monitoring Patients With Post-proton Pump Inhibitor (PPI)-Responsive Heartburn PHASE1COMPLETED
Interventional Therapy Sequential With the Fourth-generation CAR-T Targeting Nectin4/FAP for Malignant Solid Tumors PHASE1UNKNOWN
Physiological Study to Determine the Allergic Skin Activity After Different Skin Preparation PHASE1COMPLETED
The Effect of Sucralfate Slurry in Patients With Eosinophilic Esophagitis EARLY_PHASE1COMPLETED
68Ga-PMD22 PET/CT Examination Targeting CLDN18.2 EARLY_PHASE1UNKNOWN
Assessment of the 1-year Relapse Rate in Patients with Pemphigus Treated According to the Revised Pemphigus PNDS nanCOMPLETED
Evaluation of Desmoglein-3 Autoantibodies in the Tissues of Oral Lichen Planus and Correlation with Disease Severity nanNOT_YET_RECRUITING
Trichoscopy as a Monitoring Tool for Activity and Remission in Pemphigus Vulgaris: A Clinical Study Supported by Immunological Evaluation. nanNOT_YET_RECRUITING
Coagulation Activation in Patients With Pemphigus nanUNKNOWN
Evaluation of Galectin-3 in Serum and Saliva of Pemphigus Patients nanUNKNOWN
Serum IL-21 Levels in Patients With Pemphigus Vulgaris nanUNKNOWN
Trichoscopy in Diagnosis of Immunobollous Diseases nanUNKNOWN
Local Inflammation in Arrhythmogenic Right Ventricular Cardiomyopathy nanRECRUITING
Phenotypic and Functional Characterisation of Human B-cell Response in Pemphigus nanUNKNOWN
Genotype-phenotype Correlation in Junctional Epidermolysis Bullosa nanUNKNOWN
Predictive Value of E-cadherin, β-catenin and SOX4 in Recurrence and/or Progression of Non-muscle Invasive Urinary Bladder Transitional Cell Carcinoma. A Retrospective Study nanCOMPLETED
Syndecan-1 a Surrogate Marker for IBD nanCOMPLETED
Epithelial Mesenchymal Transition Markers in OSMF nanCOMPLETED
Myoglobin Removal With CytoSorb in Rhabdomyolysis nanCOMPLETED
Reversal of Epidermal Phenotype in Severe Atopic Dermatitis With Cyclosporine Therapy nanCOMPLETED
Profiling Gingival Crevicular Fluid β-Catenin Level With 8-OHdG and Total Antioxidants Capacity During Healing of Periodontal Pockets: A 3-month Clinical Trial nanNOT_YET_RECRUITING
Characterization Phenotypic and Genetic Study of the Intestinal Epithelial Dysplasia or Tufting Enteropathy (TE) nanCOMPLETED
Identification of Epidermal Signatures in Patients With Atopic Dermatitis nanUNKNOWN
Genetic Screening for Filaggrin Mutation in Atopic Dermatitis and Ichthyosis Vulgaris in the African American Population nanCOMPLETED
CircularRNA-microRNA-mRNA Regulatory Axis in IVF nanNOT_YET_RECRUITING

Related proteins — ESM-2 sequence neighbours (a DSG1 binder may also engage these)

ProteinNameSimilarity
Q9GKQ8 1.000 Q9GKQ8 →
Q7TSF0 1.000 Q7TSF0 →
Q86SJ6 1.000 Q86SJ6 →
Q7TMD7 1.000 Q7TMD7 →
Q6W3B0 1.000 Q6W3B0 →
Q3BDI7 0.999 Q3BDI7 →
Q7YRU7 0.998 Q7YRU7 →
Q7TSF1 0.995 Q7TSF1 →
Q61495 0.995 Q61495 →
Q03763 0.995 Q03763 →
O55111 0.993 O55111 →
D9PTN5 0.993 D9PTN5 →
P32926 0.993 P32926 →
F1QSQ0 0.992 F1QSQ0 →
Q14126 0.991 Q14126 →
Q8AXC7 0.990 Q8AXC7 →
O35902 0.990 O35902 →
Q9VPN2 0.989 Q9VPN2 →
Q7PNM6 0.989 Q7PNM6 →
G5EF33 0.989 G5EF33 →
P25799 0.989 P25799 →
Q24592 0.988 Q24592 →
O93436 0.988 O93436 →
O18016 0.988 O18016 →
P54816 0.988 P54816 →
G5EDW2 0.987 G5EDW2 →
O55159 0.987 O55159 →
Q18825 0.987 Q18825 →
P20792 0.987 P20792 →
P83038 0.987 P83038 →