DYNC1LI1 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

	Compound	Confidence	Supporting neighbours

Clinical trials — most relevant to DYNC1LI1 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Cornelia De Lange Syndrome: Assessing Positive Effects of Lithium Treatment	PHASE2/PHASE3	RECRUITING
Pembrolizumab (MK-3475) in MM Patients With Residual Disease	PHASE2	COMPLETED
Sirolimus Treatment in Patients With Autosomal Dominant Polycystic Kidney Disease: Renal Efficacy and Safety	PHASE2	COMPLETED
Functional Studies of Novel Genes Mutated in Primary Ciliary Dyskinesia II: Genotype to Phenotype	EARLY_PHASE1	COMPLETED
Diagnosis of Primary Ciliary Dyskinesia	nan	COMPLETED
Genetic Study of Patients With Primary Ciliary Dyskinesia	nan	COMPLETED
Characterizing the Upper Airway Manifestations in Primary Ciliary Dyskinesia and Primary Immunodeficiencies	nan	COMPLETED
Classification, Functional Stratification and Biomarkers in Ciliopathy (CILLICORIRCM)	nan	COMPLETED
NIOX VERO Nasal Application in Primary Ciliary Dyskinesia	nan	COMPLETED
Genetics of Primary Ciliary Dyskinesia	nan	COMPLETED
Early Detection and Characterization of Primary Ciliary Dyskinesia	nan	UNKNOWN
Pathogenesis of Primary Ciliary Dyskinesia (PCD) Lung Disease	nan	RECRUITING
Whole-genome Sequencing Study in Patients With Diminished Ovarian Reserve	nan	UNKNOWN
Biomarker Research in Inherited Movement Disorders	nan	RECRUITING
Genetic Studies of Strabismus, Congenital Cranial Dysinnervation Disorders (CCDDs), and Their Associated Anomalies	nan	RECRUITING
Assessing the Polygenic Burden of Rare Disruptive Mutations in Parkinson's Disease	nan	UNKNOWN
Mapping Disease Pathways for Biliary Atresia	nan	RECRUITING
PCD New Gene Discovery	nan	COMPLETED
Clinical Outcome Study for Dysferlinopathy	nan	UNKNOWN
Quantitative Assessment of the Etiologies of Megalencephaly Associated With a Detectable Tumor Risk	nan	NOT_YET_RECRUITING
The Impact of Mitochondrial Dysfunction on Human Bone Cell Metabolism and Remodelling	nan	ACTIVE_NOT_RECRUITING
A Study Providing Genetic Testing to Find Those Who May Have Primary Ciliary Dyskinesia for Potential Clinical Trials	nan	ACTIVE_NOT_RECRUITING
Peripheral Neurofilament Levels and Amyotrophic Lateral Sclerosis	nan	COMPLETED
Mapping Novel Disease Genes for Dilated Cardiomyopathy	nan	COMPLETED
Characteristics of Nondystrophic Myotonias	nan	COMPLETED
Genotype-Phenotype Correlations of Late Infantile Neuronal Ceroid Lipofuscinosis	nan	COMPLETED
Gene Mutations and Rescue in Human Congenital Diaphragmatic Hernia	nan	UNKNOWN
Autophagy in Systemic Lupus Erythematosus	nan	UNKNOWN
Nuclear Myosin VI - a Therapeutic Target in Breast Cancer	nan	UNKNOWN
Muscle Tissue Bank for Muscular Dystrophy	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a DYNC1LI1 binder may also engage these)

Protein	Name	Similarity
Q8R1Q8	—	1.000	Q8R1Q8 →
Q9QXU8	—	1.000	Q9QXU8 →
Q90828	—	0.994	Q90828 →
Q6PDL0	—	0.986	Q6PDL0 →
DYNC1LI2	Cytoplasmic dynein 1 light intermediate chain 2	0.986	landscape →
Q5RE09	—	0.985	Q5RE09 →
Q62698	—	0.983	Q62698 →
E1C065	—	0.979	E1C065 →
Q5R539	—	0.978	Q5R539 →
Q0V989	—	0.978	Q0V989 →
D3ZYR1	—	0.977	D3ZYR1 →
O43815	—	0.977	O43815 →
B5DDX6	—	0.977	B5DDX6 →
Q5EY87	—	0.976	Q5EY87 →
O08816	—	0.975	O08816 →
A4IFB1	—	0.975	A4IFB1 →
B5X165	—	0.975	B5X165 →
Q6GQN0	—	0.974	Q6GQN0 →
Q4R5P6	—	0.974	Q4R5P6 →
Q7PQ25	—	0.974	Q7PQ25 →
Q9DBA9	—	0.974	Q9DBA9 →
Q5PQS6	—	0.974	Q5PQS6 →
Q6DHL7	—	0.974	Q6DHL7 →
Q5FWH3	—	0.973	Q5FWH3 →
O60271	—	0.973	O60271 →
Q58A65	—	0.973	Q58A65 →
Q05AW9	—	0.973	Q05AW9 →
Q66I22	—	0.973	Q66I22 →
Q6NXC0	—	0.973	Q6NXC0 →
Q5ZL23	—	0.972	Q5ZL23 →