EIF2B1

Translation initiation factor eIF2B subunit alpha · Q14232 · EIF2B1 on Sugi Atlas →

0 patent compounds predicted against EIF2B1, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to EIF2B1 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Effects of Liraglutide on ER Stress in Obese Patients With Type 2 Diabetes PHASE4UNKNOWN
Status of Growth Hormone/ Insulin-like Growth Factor-1 (GH/IGF-1) Axis and Growth Failure in Ataxia Telangiectasia (AT) PHASE4UNKNOWN
Antiviral Activity and Safety of 3 Different Doses of Mifepristone in Hepatitis C Infected Patients PHASE2COMPLETED
Everolimus for Children With Recurrent or Progressive Ependymoma PHASE2COMPLETED
Study of Decitabine in Combination With Sequential Rapamycin or Ribavirin in High Risk AML Patients PHASE1/PHASE2COMPLETED
Decitabine and Venetoclax Treatment as Maintenance Therapy in Patients Post Allograft Stem Cell Transplant PHASE1/PHASE2RECRUITING
Targeting Endoplasmic Reticulum Stress in Human Hypertension PHASE1/PHASE2RECRUITING
ISIS 183750 With Irinotecan for Advanced Solid Tumors or Colorectal Cancer PHASE1/PHASE2COMPLETED
Ambroxol Therapy for Patients With Type 1 Gaucher Disease and Suboptimal Response to Enzyme Replacement Therapy PHASE2COMPLETED
A Phase Ib/II Clinical Study Evaluating the Safety and Efficacy of Tislelizumab in Combination With Golidocitinib and Selinexor for the Treatment of R/R NKTCL PHASE1/PHASE2RECRUITING
Tianasen (ASO-GNAO1) for GNAO1-Encephalopathy With Epilepsy and Movement Disorders. PHASE1/PHASE2RECRUITING
Reverse Transcriptase Inhibitors in AGS PHASE2COMPLETED
Temsirolimus and Sorafenib in Advanced Hepatocellular Carcinoma PHASE1COMPLETED
PBA Use for Treatment of ATF6-/- Patients EARLY_PHASE1SUSPENDED
Quantification of GADD34 Expression in RA nanCOMPLETED
Impact of Mutations in Aminoacyl tRNA Synthetases on Protein Translation and Cellular Stress nanWITHDRAWN
Testing of Micellar Casein, Blended Micellar Casein and Native Whey nanCOMPLETED
MEHMO Natural History and Biomarkers nanRECRUITING
Effect of Branched Chain Amino Acids on Muscle nanCOMPLETED
Association of Autophagy-related Genes ,LncRNA and SNPs With Colorectal Cancer in Egyptian Population nanCOMPLETED
Rapamycin as a Means of Interference With Reconsolidation of Posttraumatic Stress Disorder-related Traumatic Memory nanCOMPLETED
Wolfram Syndrome and WFS1-related Disorders International Registry and Clinical Study nanRECRUITING
Mitoquines in COPD nanUNKNOWN
Establishment of Human Cellular Disease Models for Wilson Disease nanCOMPLETED
Autophagy in Systemic Lupus Erythematosus nanUNKNOWN
Role of SF3B1 Mutation in Assessment of Acute and Chronic Lymphatic Leukemia nanNOT_YET_RECRUITING
Generating Intervals of Reference FFor Early Life Brain Biomarkers. nanRECRUITING
Endolymphatic Sac Tumors in a Population of Patients With Von Hippel-Lindau Disease:The Natural History and Pathobiology, and a Prospective Non-Randomized Clinical Trial of Hearing Preservation Surgery in Patients With Early Stage Endolymphatic Sac Tumors nanCOMPLETED
Effect of Non-chirurgical Periodontal Treatment on the Immune System From a Gender Perspective nanCOMPLETED
Pilot Trial of Sirolimus/MEC in High Risk Acute Myelogenous Leukemia (AML) nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a EIF2B1 binder may also engage these)

ProteinNameSimilarity
Q5RAR0 1.000 Q5RAR0 →
Q4R4V8 1.000 Q4R4V8 →
Q99LC8 1.000 Q99LC8 →
Q0IIF2 1.000 Q0IIF2 →
Q64270 1.000 Q64270 →
P14741 1.000 P14741 →
P34604 0.999 P34604 →
B6K4Q2 0.991 B6K4Q2 →
Q54I81 0.990 Q54I81 →
Q9USP0 0.990 Q9USP0 →
P00927 0.989 P00927 →
A6ZP88 0.988 A6ZP88 →
A1CGN9 0.988 A1CGN9 →
P78875 0.988 P78875 →
Q9ZUG4 0.987 Q9ZUG4 →
Q9T079 0.987 Q9T079 →
A1CY38 0.987 A1CY38 →
B4NG41 0.987 B4NG41 →
Q16I17 0.987 Q16I17 →
Q8VY78 0.987 Q8VY78 →
A7RF00 0.986 A7RF00 →
Q9V9X4 0.986 Q9V9X4 →
B4GYU1 0.986 B4GYU1 →
Q9SHG0 0.986 Q9SHG0 →
A8WJ41 0.986 A8WJ41 →
A7N6Q6 0.986 A7N6Q6 →
Q46VX8 0.986 Q46VX8 →
O94313 0.986 O94313 →
B0XDC4 0.986 B0XDC4 →
Q97QA9 0.986 Q97QA9 →