EIF2B2

Translation initiation factor eIF2B subunit beta · P49770 · EIF2B2 on Sugi Atlas →

0 patent compounds predicted against EIF2B2, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to EIF2B2 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Effects of Liraglutide on ER Stress in Obese Patients With Type 2 Diabetes PHASE4UNKNOWN
Strategies to Reduce Organic Muscle Atrophy in the Intensive Care Unit PHASE2/PHASE3WITHDRAWN
Antiviral Activity and Safety of 3 Different Doses of Mifepristone in Hepatitis C Infected Patients PHASE2COMPLETED
Everolimus for Children With Recurrent or Progressive Ependymoma PHASE2COMPLETED
A Phase Ib/II Clinical Study Evaluating the Safety and Efficacy of Tislelizumab in Combination With Golidocitinib and Selinexor for the Treatment of R/R NKTCL PHASE1/PHASE2RECRUITING
Targeting Endoplasmic Reticulum Stress in Human Hypertension PHASE1/PHASE2RECRUITING
ISIS 183750 With Irinotecan for Advanced Solid Tumors or Colorectal Cancer PHASE1/PHASE2COMPLETED
Study of Decitabine in Combination With Sequential Rapamycin or Ribavirin in High Risk AML Patients PHASE1/PHASE2COMPLETED
Decitabine and Venetoclax Treatment as Maintenance Therapy in Patients Post Allograft Stem Cell Transplant PHASE1/PHASE2RECRUITING
Ambroxol Therapy for Patients With Type 1 Gaucher Disease and Suboptimal Response to Enzyme Replacement Therapy PHASE2COMPLETED
Tianasen (ASO-GNAO1) for GNAO1-Encephalopathy With Epilepsy and Movement Disorders. PHASE1/PHASE2RECRUITING
Temsirolimus and Sorafenib in Advanced Hepatocellular Carcinoma PHASE1COMPLETED
Application of mRNA Immunotherapy Technology in Epstein-Barr Virus-related Refractory Malignant Tumors PHASE1ACTIVE_NOT_RECRUITING
PBA Use for Treatment of ATF6-/- Patients EARLY_PHASE1SUSPENDED
Quantification of GADD34 Expression in RA nanCOMPLETED
Testing of Micellar Casein, Blended Micellar Casein and Native Whey nanCOMPLETED
MEHMO Natural History and Biomarkers nanRECRUITING
Impact of Mutations in Aminoacyl tRNA Synthetases on Protein Translation and Cellular Stress nanWITHDRAWN
Effect of Branched Chain Amino Acids on Muscle nanCOMPLETED
Rapamycin as a Means of Interference With Reconsolidation of Posttraumatic Stress Disorder-related Traumatic Memory nanCOMPLETED
Endolymphatic Sac Tumors in a Population of Patients With Von Hippel-Lindau Disease:The Natural History and Pathobiology, and a Prospective Non-Randomized Clinical Trial of Hearing Preservation Surgery in Patients With Early Stage Endolymphatic Sac Tumors nanCOMPLETED
Generating Intervals of Reference FFor Early Life Brain Biomarkers. nanRECRUITING
Non-invasive Remote Ischemic PreConditioning (RIPC) in Free Flaps for Breast Reconstruction nanCOMPLETED
Autophagy in Systemic Lupus Erythematosus nanUNKNOWN
Wolfram Syndrome and WFS1-related Disorders International Registry and Clinical Study nanRECRUITING
Association of Autophagy-related Genes ,LncRNA and SNPs With Colorectal Cancer in Egyptian Population nanCOMPLETED
Establishment of Human Cellular Disease Models for Wilson Disease nanCOMPLETED
Prognosis Assessment of the Increase of GADD34 Gene Expression for Patient Suffering From Systemic Lupus Erythematosus nanCOMPLETED
Autophagy Bladder Cancer nanUNKNOWN
Circulating Biomarker Signatures for the Detection of Gastric Preneoplasia and Cancer nanRECRUITING

Related proteins — ESM-2 sequence neighbours (a EIF2B2 binder may also engage these)

ProteinNameSimilarity
Q99LD9 1.000 Q99LD9 →
Q28690 1.000 Q28690 →
Q5E9B4 0.997 Q5E9B4 →
Q62818 0.996 Q62818 →
Q90511 0.996 Q90511 →
Q9H871 0.962 Q9H871 →
ERCC4 DNA repair endonuclease XPF (EC 3.1.-.-) (DNA 0.962 landscape →
Q6DFF4 0.961 Q6DFF4 →
Q32NG4 0.961 Q32NG4 →
Q9QYM7 0.960 Q9QYM7 →
Q5IH13 0.960 Q5IH13 →
Q2KIX2 0.960 Q2KIX2 →
O23617 0.960 O23617 →
Q9NXN4 0.960 Q9NXN4 →
Q66H63 0.959 Q66H63 →
Q5ZJV4 0.959 Q5ZJV4 →
Q80YQ8 0.959 Q80YQ8 →
PDS5A Sister chromatid cohesion protein PDS5 homolog A 0.959 landscape →
Q8W4M7 0.959 Q8W4M7 →
Q8K114 0.958 Q8K114 →
Q05B56 0.958 Q05B56 →
Q8WUH2 0.958 Q8WUH2 →
Q6IQS6 0.958 Q6IQS6 →
Q4R5Z4 0.958 Q4R5Z4 →
Q5R6E0 0.958 Q5R6E0 →
WDR36 WD repeat-containing protein 36 0.958 landscape →
Q640V2 0.958 Q640V2 →
Q9JLB0 0.958 Q9JLB0 →
Q9CWF6 0.958 Q9CWF6 →
SNRNP200 U5 small nuclear ribonucleoprotein 200 kDa helicase 0.958 landscape →