EIF2B4

Translation initiation factor eIF2B subunit delta · Q9UI10 · EIF2B4 on Sugi Atlas →

0 patent compounds predicted against EIF2B4, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to EIF2B4 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Effects of Liraglutide on ER Stress in Obese Patients With Type 2 Diabetes PHASE4UNKNOWN
Antiviral Activity and Safety of 3 Different Doses of Mifepristone in Hepatitis C Infected Patients PHASE2COMPLETED
Everolimus for Children With Recurrent or Progressive Ependymoma PHASE2COMPLETED
Decitabine and Venetoclax Treatment as Maintenance Therapy in Patients Post Allograft Stem Cell Transplant PHASE1/PHASE2RECRUITING
Selumetinib With or Without Temsirolimus in Treating Patients With Metastatic, Recurrent, or Locally Advanced Soft Tissue Sarcoma That Cannot Be Removed By Surgery PHASE2COMPLETED
Study of Decitabine in Combination With Sequential Rapamycin or Ribavirin in High Risk AML Patients PHASE1/PHASE2COMPLETED
Targeting Endoplasmic Reticulum Stress in Human Hypertension PHASE1/PHASE2RECRUITING
ISIS 183750 With Irinotecan for Advanced Solid Tumors or Colorectal Cancer PHASE1/PHASE2COMPLETED
Ambroxol Therapy for Patients With Type 1 Gaucher Disease and Suboptimal Response to Enzyme Replacement Therapy PHASE2COMPLETED
A Phase Ib/II Clinical Study Evaluating the Safety and Efficacy of Tislelizumab in Combination With Golidocitinib and Selinexor for the Treatment of R/R NKTCL PHASE1/PHASE2RECRUITING
Temsirolimus and Sorafenib in Advanced Hepatocellular Carcinoma PHASE1COMPLETED
PBA Use for Treatment of ATF6-/- Patients EARLY_PHASE1SUSPENDED
Quantification of GADD34 Expression in RA nanCOMPLETED
Impact of Mutations in Aminoacyl tRNA Synthetases on Protein Translation and Cellular Stress nanWITHDRAWN
Testing of Micellar Casein, Blended Micellar Casein and Native Whey nanCOMPLETED
MEHMO Natural History and Biomarkers nanRECRUITING
Effect of Branched Chain Amino Acids on Muscle nanCOMPLETED
Wolfram Syndrome and WFS1-related Disorders International Registry and Clinical Study nanRECRUITING
Autophagy in Systemic Lupus Erythematosus nanUNKNOWN
Rapamycin as a Means of Interference With Reconsolidation of Posttraumatic Stress Disorder-related Traumatic Memory nanCOMPLETED
Pilot Trial of Sirolimus/MEC in High Risk Acute Myelogenous Leukemia (AML) nanCOMPLETED
Association of Autophagy-related Genes ,LncRNA and SNPs With Colorectal Cancer in Egyptian Population nanCOMPLETED
Prevalence of a Non-Expressing 11B Mutation in Aka Peoples of the Central African Republic nanCOMPLETED
Establishment of Human Cellular Disease Models for Wilson Disease nanCOMPLETED
Endolymphatic Sac Tumors in a Population of Patients With Von Hippel-Lindau Disease:The Natural History and Pathobiology, and a Prospective Non-Randomized Clinical Trial of Hearing Preservation Surgery in Patients With Early Stage Endolymphatic Sac Tumors nanCOMPLETED
Role of Amino Acids and Genetic Disorder in Pathogenesis of Heart Failure nanUNKNOWN
Regulation of Lymphocyte Anti-tumor Response in Metastatic Patients Treated With the mTOR Inhibitor Everolimus nanCOMPLETED
Mitoquines in COPD nanUNKNOWN
Immunological Profile and Clinical Characteristics of Children Diagnosed With Chronic Granulomatous Disease nanUNKNOWN
SMYD3-Driven Metabolic Rewiring in Colorectal Liver Metastases nanNOT_YET_RECRUITING

Related proteins — ESM-2 sequence neighbours (a EIF2B4 binder may also engage these)

ProteinNameSimilarity
Q63186 1.000 Q63186 →
P41111 1.000 P41111 →
Q3T058 1.000 Q3T058 →
Q61749 1.000 Q61749 →
F1QWK4 0.977 F1QWK4 →
Q8BML1 0.976 Q8BML1 →
Q9NRL3 0.973 Q9NRL3 →
Q9NQ55 0.971 Q9NQ55 →
P37913 0.971 P37913 →
P51432 0.971 P51432 →
Q68G30 0.971 Q68G30 →
Q8VDP3 0.971 Q8VDP3 →
Q9UJY4 0.970 Q9UJY4 →
Q91W40 0.970 Q91W40 →
D4A1F2 0.970 D4A1F2 →
Q5REM3 0.970 Q5REM3 →
P70218 0.970 P70218 →
Q8BMI3 0.970 Q8BMI3 →
F1RA39 0.969 F1RA39 →
Q8CG07 0.969 Q8CG07 →
P58404 0.969 P58404 →
O88509 0.969 O88509 →
Q9Y613 0.969 Q9Y613 →
O94851 0.968 O94851 →
Q148G5 0.968 Q148G5 →
D3ZBP4 0.968 D3ZBP4 →
Q8TDZ2 0.968 Q8TDZ2 →
F1MF74 0.968 F1MF74 →
PLCB3 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 0.968 landscape →
A0A0R4IMY7 0.968 A0A0R4IMY7 →