EIF2B5

Translation initiation factor eIF2B subunit epsilon · Q13144 · EIF2B5 on Sugi Atlas →

0 patent compounds predicted against EIF2B5, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to EIF2B5 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Effects of Liraglutide on ER Stress in Obese Patients With Type 2 Diabetes PHASE4UNKNOWN
Status of Growth Hormone/ Insulin-like Growth Factor-1 (GH/IGF-1) Axis and Growth Failure in Ataxia Telangiectasia (AT) PHASE4UNKNOWN
Antiviral Activity and Safety of 3 Different Doses of Mifepristone in Hepatitis C Infected Patients PHASE2COMPLETED
Everolimus for Children With Recurrent or Progressive Ependymoma PHASE2COMPLETED
ISIS 183750 With Irinotecan for Advanced Solid Tumors or Colorectal Cancer PHASE1/PHASE2COMPLETED
Targeting Endoplasmic Reticulum Stress in Human Hypertension PHASE1/PHASE2RECRUITING
Study of Decitabine in Combination With Sequential Rapamycin or Ribavirin in High Risk AML Patients PHASE1/PHASE2COMPLETED
Selumetinib With or Without Temsirolimus in Treating Patients With Metastatic, Recurrent, or Locally Advanced Soft Tissue Sarcoma That Cannot Be Removed By Surgery PHASE2COMPLETED
Decitabine and Venetoclax Treatment as Maintenance Therapy in Patients Post Allograft Stem Cell Transplant PHASE1/PHASE2RECRUITING
Ambroxol Therapy for Patients With Type 1 Gaucher Disease and Suboptimal Response to Enzyme Replacement Therapy PHASE2COMPLETED
A Phase Ib/II Clinical Study Evaluating the Safety and Efficacy of Tislelizumab in Combination With Golidocitinib and Selinexor for the Treatment of R/R NKTCL PHASE1/PHASE2RECRUITING
Tianasen (ASO-GNAO1) for GNAO1-Encephalopathy With Epilepsy and Movement Disorders. PHASE1/PHASE2RECRUITING
Temsirolimus and Sorafenib in Advanced Hepatocellular Carcinoma PHASE1COMPLETED
Application of mRNA Immunotherapy Technology in Epstein-Barr Virus-related Refractory Malignant Tumors PHASE1ACTIVE_NOT_RECRUITING
PBA Use for Treatment of ATF6-/- Patients EARLY_PHASE1SUSPENDED
Quantification of GADD34 Expression in RA nanCOMPLETED
Impact of Mutations in Aminoacyl tRNA Synthetases on Protein Translation and Cellular Stress nanWITHDRAWN
Testing of Micellar Casein, Blended Micellar Casein and Native Whey nanCOMPLETED
MEHMO Natural History and Biomarkers nanRECRUITING
Effect of Branched Chain Amino Acids on Muscle nanCOMPLETED
Autophagy in Systemic Lupus Erythematosus nanUNKNOWN
Rapamycin as a Means of Interference With Reconsolidation of Posttraumatic Stress Disorder-related Traumatic Memory nanCOMPLETED
Endolymphatic Sac Tumors in a Population of Patients With Von Hippel-Lindau Disease:The Natural History and Pathobiology, and a Prospective Non-Randomized Clinical Trial of Hearing Preservation Surgery in Patients With Early Stage Endolymphatic Sac Tumors nanCOMPLETED
Generating Intervals of Reference FFor Early Life Brain Biomarkers. nanRECRUITING
Establishment of Human Cellular Disease Models for Wilson Disease nanCOMPLETED
Wolfram Syndrome and WFS1-related Disorders International Registry and Clinical Study nanRECRUITING
Non-invasive Remote Ischemic PreConditioning (RIPC) in Free Flaps for Breast Reconstruction nanCOMPLETED
GADD34 and Type I IFN Response Genes in SLE nanCOMPLETED
Association of Autophagy-related Genes ,LncRNA and SNPs With Colorectal Cancer in Egyptian Population nanCOMPLETED
Circulating Biomarker Signatures for the Detection of Gastric Preneoplasia and Cancer nanRECRUITING

Related proteins — ESM-2 sequence neighbours (a EIF2B5 binder may also engage these)

ProteinNameSimilarity
P47823 1.000 P47823 →
Q64350 1.000 Q64350 →
Q8CHW4 1.000 Q8CHW4 →
A7MB11 0.980 A7MB11 →
Q5NVK5 0.979 Q5NVK5 →
A4IG72 0.979 A4IG72 →
Q8ND23 0.979 Q8ND23 →
Q14181 0.979 Q14181 →
Q5CZL1 0.979 Q5CZL1 →
Q9NVU0 0.979 Q9NVU0 →
Q3UR70 0.979 Q3UR70 →
Q5EA80 0.978 Q5EA80 →
Q9UNS1 0.978 Q9UNS1 →
Q08DJ7 0.978 Q08DJ7 →
Q9ESJ4 0.978 Q9ESJ4 →
A5A779 0.978 A5A779 →
Q28DV7 0.977 Q28DV7 →
Q8WUH2 0.977 Q8WUH2 →
Q9Z2Y1 0.977 Q9Z2Y1 →
Q7ZYP6 0.977 Q7ZYP6 →
INF2 Inverted formin-2 0.977 landscape →
Q9UJY4 0.977 Q9UJY4 →
Q6ZT62 0.977 Q6ZT62 →
Q7TMC8 0.977 Q7TMC8 →
P98192 0.976 P98192 →
Q9R1X4 0.976 Q9R1X4 →
A5PK19 0.976 A5PK19 →
Q0GNC1 0.976 Q0GNC1 →
P33611 0.976 P33611 →
Q3UFQ8 0.976 Q3UFQ8 →