EIF2S2

Eukaryotic translation initiation factor 2 subunit 2 · P20042 · EIF2S2 on Sugi Atlas →

0 patent compounds predicted against EIF2S2, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to EIF2S2 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Effects of Liraglutide on ER Stress in Obese Patients With Type 2 Diabetes PHASE4UNKNOWN
Antiviral Activity and Safety of 3 Different Doses of Mifepristone in Hepatitis C Infected Patients PHASE2COMPLETED
Everolimus for Children With Recurrent or Progressive Ependymoma PHASE2COMPLETED
ISIS 183750 With Irinotecan for Advanced Solid Tumors or Colorectal Cancer PHASE1/PHASE2COMPLETED
Targeting Endoplasmic Reticulum Stress in Human Hypertension PHASE1/PHASE2RECRUITING
Study of Decitabine in Combination With Sequential Rapamycin or Ribavirin in High Risk AML Patients PHASE1/PHASE2COMPLETED
Decitabine and Venetoclax Treatment as Maintenance Therapy in Patients Post Allograft Stem Cell Transplant PHASE1/PHASE2RECRUITING
A Study of Hydroxychloroquine in Combination With Gemcitabine/Abraxane in Pancreatic Cancer PHASE1/PHASE2COMPLETED
Temsirolimus and Sorafenib in Advanced Hepatocellular Carcinoma PHASE1COMPLETED
Chinese Herbal Formulation PHY906 and Sorafenib Tosylate in Treating Patients With Advanced Liver Cancer PHASE1COMPLETED
Treatment Duration Increment and Pharmacodynamic Study of CX-4945 in Patients With Basal Cell Carcinoma (BCC) PHASE1COMPLETED
PBA Use for Treatment of ATF6-/- Patients EARLY_PHASE1SUSPENDED
Quantification of GADD34 Expression in RA nanCOMPLETED
MEHMO Natural History and Biomarkers nanRECRUITING
Endolymphatic Sac Tumors in a Population of Patients With Von Hippel-Lindau Disease:The Natural History and Pathobiology, and a Prospective Non-Randomized Clinical Trial of Hearing Preservation Surgery in Patients With Early Stage Endolymphatic Sac Tumors nanCOMPLETED
Effect of Branched Chain Amino Acids on Muscle nanCOMPLETED
Impact of Mutations in Aminoacyl tRNA Synthetases on Protein Translation and Cellular Stress nanWITHDRAWN
The Effects of Whey vs. Collagen on MPS nanCOMPLETED
Rapamycin as a Means of Interference With Reconsolidation of Posttraumatic Stress Disorder-related Traumatic Memory nanCOMPLETED
Autophagy Bladder Cancer nanUNKNOWN
MiRNA223 and HMGB1 as Apredictos for Drug Resistant Epilepsy nanUNKNOWN
Regulation of Lymphocyte Anti-tumor Response in Metastatic Patients Treated With the mTOR Inhibitor Everolimus nanCOMPLETED
miR-155 Expression in Episodic and Chronic Migraine nanUNKNOWN
Pilot Trial of Sirolimus/MEC in High Risk Acute Myelogenous Leukemia (AML) nanCOMPLETED
Molecular Phenotype Changes and Personalized Treatment for CRPC nanUNKNOWN
Establishment of Human Cellular Disease Models for Wilson Disease nanCOMPLETED
Role of SF3B1 Mutation in Assessment of Acute and Chronic Lymphatic Leukemia nanNOT_YET_RECRUITING
Autophagy in Systemic Lupus Erythematosus nanUNKNOWN
Muscle Regrowth During Physical Rehabilitation and Amino Acid Supplementation nanCOMPLETED
MicroRNA-1 (miRNA-1) and MicroRNA-133a (miRNA-133a) Levels After Acute Exercise in Ultimate Frisbee Athletes nanUNKNOWN

Related proteins — ESM-2 sequence neighbours (a EIF2S2 binder may also engage these)

ProteinNameSimilarity
Q5R4T9 1.000 Q5R4T9 →
Q99L45 1.000 Q99L45 →
Q5E9D0 1.000 Q5E9D0 →
P41035 1.000 P41035 →
P41375 0.994 P41375 →
P56329 0.993 P56329 →
Q41969 0.993 Q41969 →
O24473 0.992 O24473 →
Q07205 0.991 Q07205 →
Q21230 0.990 Q21230 →
P09064 0.990 P09064 →
P55871 0.990 P55871 →
P55010 0.988 P55010 →
P59325 0.987 P59325 →
Q54T27 0.985 Q54T27 →
Q5R4L0 0.985 Q5R4L0 →
Q3SYW6 0.984 Q3SYW6 →
O60182 0.984 O60182 →
Q6P1V4 0.983 Q6P1V4 →
Q9C8F1 0.983 Q9C8F1 →
B4HMY3 0.983 B4HMY3 →
B3MIF1 0.982 B3MIF1 →
Q4QR58 0.982 Q4QR58 →
B3NML0 0.982 B3NML0 →
Q22918 0.982 Q22918 →
Q9VXK6 0.982 Q9VXK6 →
B4P562 0.982 B4P562 →
EIF3C Eukaryotic translation initiation factor 3 subunit C 0.982 landscape →
B5ME19 0.982 B5ME19 →
Q09689 0.981 Q09689 →