EIF3A

Eukaryotic translation initiation factor 3 subunit A · Q14152 · EIF3A on Sugi Atlas →

0 patent compounds predicted against EIF3A, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to EIF3A by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Effects of Liraglutide on ER Stress in Obese Patients With Type 2 Diabetes PHASE4UNKNOWN
Antiviral Activity and Safety of 3 Different Doses of Mifepristone in Hepatitis C Infected Patients PHASE2COMPLETED
ISIS 183750 With Irinotecan for Advanced Solid Tumors or Colorectal Cancer PHASE1/PHASE2COMPLETED
Everolimus for Children With Recurrent or Progressive Ependymoma PHASE2COMPLETED
Decitabine and Venetoclax Treatment as Maintenance Therapy in Patients Post Allograft Stem Cell Transplant PHASE1/PHASE2RECRUITING
Study of Decitabine in Combination With Sequential Rapamycin or Ribavirin in High Risk AML Patients PHASE1/PHASE2COMPLETED
A Study of Hydroxychloroquine in Combination With Gemcitabine/Abraxane in Pancreatic Cancer PHASE1/PHASE2COMPLETED
A Phase Ib/II Clinical Study Evaluating the Safety and Efficacy of Tislelizumab in Combination With Golidocitinib and Selinexor for the Treatment of R/R NKTCL PHASE1/PHASE2RECRUITING
Targeting Endoplasmic Reticulum Stress in Human Hypertension PHASE1/PHASE2RECRUITING
Temsirolimus and Sorafenib in Advanced Hepatocellular Carcinoma PHASE1COMPLETED
Treatment Duration Increment and Pharmacodynamic Study of CX-4945 in Patients With Basal Cell Carcinoma (BCC) PHASE1COMPLETED
Chinese Herbal Formulation PHY906 and Sorafenib Tosylate in Treating Patients With Advanced Liver Cancer PHASE1COMPLETED
Quantification of GADD34 Expression in RA nanCOMPLETED
Impact of Mutations in Aminoacyl tRNA Synthetases on Protein Translation and Cellular Stress nanWITHDRAWN
MEHMO Natural History and Biomarkers nanRECRUITING
Endolymphatic Sac Tumors in a Population of Patients With Von Hippel-Lindau Disease:The Natural History and Pathobiology, and a Prospective Non-Randomized Clinical Trial of Hearing Preservation Surgery in Patients With Early Stage Endolymphatic Sac Tumors nanCOMPLETED
Effect of Branched Chain Amino Acids on Muscle nanCOMPLETED
MiRNA223 and HMGB1 as Apredictos for Drug Resistant Epilepsy nanUNKNOWN
Prognostic Value of Protein IMP3 Expression in Cervical Cancer nanCOMPLETED
SMYD3-Driven Metabolic Rewiring in Colorectal Liver Metastases nanNOT_YET_RECRUITING
Autophagy in Systemic Lupus Erythematosus nanUNKNOWN
Autophagy Bladder Cancer nanUNKNOWN
miR-155 Expression in Episodic and Chronic Migraine nanUNKNOWN
Role of SF3B1 Mutation in Assessment of Acute and Chronic Lymphatic Leukemia nanNOT_YET_RECRUITING
Molecular Phenotype Changes and Personalized Treatment for CRPC nanUNKNOWN
A Study of Serum Protein Profiling in Patients With Non-Small Cell Lung Cancer Treated With Gefitinib or Erlotinib nanCOMPLETED
Predictive Value of Maternal Blood Protein Signatures in Preterm Birth nanCOMPLETED
Differential Gene Expression of Liver Tissue and Blood From Individuals With Chronic Viral Hepatitis nanUNKNOWN
MicroRNA-1 (miRNA-1) and MicroRNA-133a (miRNA-133a) Levels After Acute Exercise in Ultimate Frisbee Athletes nanUNKNOWN
Pilot Trial of Sirolimus/MEC in High Risk Acute Myelogenous Leukemia (AML) nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a EIF3A binder may also engage these)

ProteinNameSimilarity
Q1JU68 1.000 Q1JU68 →
P23116 1.000 P23116 →
Q6PCR7 1.000 Q6PCR7 →
A2VD00 1.000 A2VD00 →
A4II09 1.000 A4II09 →
Q40554 0.993 Q40554 →
Q9JKB8 0.979 Q9JKB8 →
A2AT37 0.979 A2AT37 →
Q5ZJ85 0.979 Q5ZJ85 →
Q922U1 0.979 Q922U1 →
Q6P4T2 0.978 Q6P4T2 →
Q5RE03 0.978 Q5RE03 →
O49160 0.977 O49160 →
Q5R644 0.977 Q5R644 →
Q99633 0.977 Q99633 →
Q9LD55 0.977 Q9LD55 →
Q5R5F1 0.977 Q5R5F1 →
A4GWN3 0.977 A4GWN3 →
Q62383 0.977 Q62383 →
SNRNP200 U5 small nuclear ribonucleoprotein 200 kDa helicase 0.977 landscape →
Q8IWV8 0.977 Q8IWV8 →
Q2HJ41 0.977 Q2HJ41 →
Q8BM39 0.977 Q8BM39 →
Q2KIA6 0.976 Q2KIA6 →
GTF3C3 General transcription factor 3C polypeptide 3 0.976 landscape →
Q7KZ85 0.976 Q7KZ85 →
Q9JKF1 0.975 Q9JKF1 →
Q8C735 0.974 Q8C735 →
Q3ZCK1 0.974 Q3ZCK1 →
Q8BWQ6 0.974 Q8BWQ6 →