EIF3B

Eukaryotic translation initiation factor 3 subunit B · P55884 · EIF3B on Sugi Atlas →

0 patent compounds predicted against EIF3B, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to EIF3B by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Effects of Liraglutide on ER Stress in Obese Patients With Type 2 Diabetes PHASE4UNKNOWN
Antiviral Activity and Safety of 3 Different Doses of Mifepristone in Hepatitis C Infected Patients PHASE2COMPLETED
ISIS 183750 With Irinotecan for Advanced Solid Tumors or Colorectal Cancer PHASE1/PHASE2COMPLETED
Everolimus for Children With Recurrent or Progressive Ependymoma PHASE2COMPLETED
Decitabine and Venetoclax Treatment as Maintenance Therapy in Patients Post Allograft Stem Cell Transplant PHASE1/PHASE2RECRUITING
A Study of Hydroxychloroquine in Combination With Gemcitabine/Abraxane in Pancreatic Cancer PHASE1/PHASE2COMPLETED
Cediranib Maleate in Treating Patients With Recurrent or Persistent Endometrial Cancer PHASE2COMPLETED
Study of Decitabine in Combination With Sequential Rapamycin or Ribavirin in High Risk AML Patients PHASE1/PHASE2COMPLETED
A Phase Ib/II Clinical Study Evaluating the Safety and Efficacy of Tislelizumab in Combination With Golidocitinib and Selinexor for the Treatment of R/R NKTCL PHASE1/PHASE2RECRUITING
Anastrozole or Fulvestrant in Treating Postmenopausal Patients With Breast Cancer PHASE2COMPLETED
Temsirolimus and Sorafenib in Advanced Hepatocellular Carcinoma PHASE1COMPLETED
Treatment Duration Increment and Pharmacodynamic Study of CX-4945 in Patients With Basal Cell Carcinoma (BCC) PHASE1COMPLETED
Chinese Herbal Formulation PHY906 and Sorafenib Tosylate in Treating Patients With Advanced Liver Cancer PHASE1COMPLETED
PBA Use for Treatment of ATF6-/- Patients EARLY_PHASE1SUSPENDED
Quantification of GADD34 Expression in RA nanCOMPLETED
MEHMO Natural History and Biomarkers nanRECRUITING
Endolymphatic Sac Tumors in a Population of Patients With Von Hippel-Lindau Disease:The Natural History and Pathobiology, and a Prospective Non-Randomized Clinical Trial of Hearing Preservation Surgery in Patients With Early Stage Endolymphatic Sac Tumors nanCOMPLETED
Impact of Mutations in Aminoacyl tRNA Synthetases on Protein Translation and Cellular Stress nanWITHDRAWN
Role of SF3B1 Mutation in Assessment of Acute and Chronic Lymphatic Leukemia nanNOT_YET_RECRUITING
MiRNA223 and HMGB1 as Apredictos for Drug Resistant Epilepsy nanUNKNOWN
Prognostic Value of Protein IMP3 Expression in Cervical Cancer nanCOMPLETED
Effect of Branched Chain Amino Acids on Muscle nanCOMPLETED
Autophagy Bladder Cancer nanUNKNOWN
Predictive Value of Maternal Blood Protein Signatures in Preterm Birth nanCOMPLETED
miR-155 Expression in Episodic and Chronic Migraine nanUNKNOWN
SMYD3-Driven Metabolic Rewiring in Colorectal Liver Metastases nanNOT_YET_RECRUITING
Autophagy in Systemic Lupus Erythematosus nanUNKNOWN
Molecular Phenotype Changes and Personalized Treatment for CRPC nanUNKNOWN
A Study of Serum Protein Profiling in Patients With Non-Small Cell Lung Cancer Treated With Gefitinib or Erlotinib nanCOMPLETED
Testing of Micellar Casein, Blended Micellar Casein and Native Whey nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a EIF3B binder may also engage these)

ProteinNameSimilarity
Q4G061 0.998 Q4G061 →
Q8JZQ9 0.996 Q8JZQ9 →
A7MB16 0.996 A7MB16 →
Q569Z1 0.983 Q569Z1 →
Q676U5 0.967 Q676U5 →
Q8QFR2 0.967 Q8QFR2 →
Q5ZL38 0.967 Q5ZL38 →
Q9H269 0.965 Q9H269 →
Q5RAC9 0.965 Q5RAC9 →
CHAF1B Chromatin assembly factor 1 subunit B 0.964 landscape →
P0C606 0.964 P0C606 →
TAF5 Transcription initiation factor TFIID subunit 5 0.963 landscape →
Q8C092 0.962 Q8C092 →
P79987 0.962 P79987 →
Q91W86 0.962 Q91W86 →
MAP3K20 Mitogen-activated protein kinase kinase kinase 20 0.962 landscape →
HIRA Protein HIRA 0.962 landscape →
Q08E57 0.962 Q08E57 →
Q7TSG1 0.962 Q7TSG1 →
Q9CZT4 0.962 Q9CZT4 →
B0KWQ2 0.961 B0KWQ2 →
Q6PDL0 0.961 Q6PDL0 →
Q5R7L2 0.961 Q5R7L2 →
P58405 0.961 P58405 →
Q4KUS2 0.961 Q4KUS2 →
Q8BHL5 0.961 Q8BHL5 →
Q5XIJ6 0.961 Q5XIJ6 →
Q1JU68 0.961 Q1JU68 →
O14562 0.961 O14562 →
Q15413 0.961 Q15413 →