ENO1

Alpha-enolase · P06733 · ENO1 on Sugi Atlas →

1,014 patent compounds predicted against ENO1, 505 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL18077402 SCHEMBL18077402 1.00 5/20
SCHEMBL18077425 SCHEMBL18077425 1.00 5/20
SCHEMBL18077428 SCHEMBL18077428 0.89 5/20
SCHEMBL18077430 SCHEMBL18077430 0.89 5/20
SCHEMBL23884933 SCHEMBL23884933 0.75 5/20
SCHEMBL25544345 SCHEMBL25544345 0.73 5/20
SCHEMBL22266053 SCHEMBL22266053 0.72 5/20
SCHEMBL22266051 SCHEMBL22266051 0.71 5/20
SCHEMBL22266144 SCHEMBL22266144 0.69 5/20
SCHEMBL22266143 SCHEMBL22266143 0.60 5/20
SCHEMBL18048512 SCHEMBL18048512 1.00 4/20
SCHEMBL18077399 SCHEMBL18077399 1.00 4/20
SCHEMBL18077405 SCHEMBL18077405 1.00 4/20
SCHEMBL18077414 SCHEMBL18077414 1.00 4/20
SCHEMBL18077424 SCHEMBL18077424 1.00 4/20
SCHEMBL18077426 SCHEMBL18077426 1.00 4/20
SCHEMBL22275838 SCHEMBL22275838 1.00 4/20
SCHEMBL25544138 SCHEMBL25544138 0.84 4/20
SCHEMBL22265938 SCHEMBL22265938 0.83 4/20
SCHEMBL25544137 SCHEMBL25544137 0.82 4/20

Clinical trials — most relevant to ENO1 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
68 Gallium-Fibroblast Activating Protein Inhibitors-46 Positron Emission Tomography - Computerized Tomography for Molecular Assessment of Fibroblast Activation and Risk Assessment in Solid Tumors PHASE2UNKNOWN
A Trial of CDX-1401 in Combination With Poly-ICLC and Pembrolizumab, in Previously Treated Advanced Solid Tumor Patients PHASE1/PHASE2WITHDRAWN
Desferal Administration to Improve the Impaired Reaction to Hypoxia in Diabetes PHASE2UNKNOWN
A Vaccine Study for High Risk Cancers PHASE1WITHDRAWN
Dose Escalation Study of Immunomodulatory Nanoparticles PHASE1ACTIVE_NOT_RECRUITING
NY-ESO-1 Protein With Montanide and CpG 7909 as Cancer Vaccine in Several Tumors PHASE1COMPLETED
Neuron Specific Enolase in Ventricular Assist Device Recipients nanCOMPLETED
Clinicolaboratory Predictors of Outcome in Children With Encephalitis nanNOT_YET_RECRUITING
S100β and Neuron Specific Enolase Levels in Liver Transplantation nanCOMPLETED
Foci of Tumor Heterogeneity in Diffuse Low-Grade Gliomas nanCOMPLETED
Evaluation of Neuronal Damage in Patients Undergoing Robot-assisted Laparoscopic Radical Prostatectomy With Biomarkers nanUNKNOWN
Predictive Model for the Occurrence of Cerebral Vasospasm Complicating Subarachnoid Haemorrhage by Combined Analysis of the Kinetics of a Panel of Biomarkers. nanCOMPLETED
Role of Concentration of Biomarkers S100B and NSE in Serum in Mild and Moderate Head Trauma nanUNKNOWN
Role of Brain Specific Biomarkers in Hydrocephalus nanCOMPLETED
Neuropsychometric Outcome After Carotid Endarterectomy nanCOMPLETED
ALDOA Expression in Bladder Urothelial Carcinoma nanNOT_YET_RECRUITING
Neurorehabilitation in Patients With Disorders of Consciousness: Multidimensional Ambispective Study on the Impact of Single and Combined Approaches nanRECRUITING
Sepsis Associated Encephalopathy (SAE) Biomarkers nanACTIVE_NOT_RECRUITING
Predicting Postoperative Delirium With Heart Rate Variability Obtained by Analgesia Nociception Index nanNOT_YET_RECRUITING
Biomarkers And Neurological Outcome in Neonates (BANON) nanCOMPLETED
Using Next-generation Sequencing in the Diagnosis of Epilepsy and/or Intellectual Disability in a Pediatric Cohorte nanCOMPLETED
Neuroprotective Effect of Mild Hypothermia Versus Normothermia During Cardiopulmonary Bypass of Coronary Artery Surgery nanNOT_YET_RECRUITING
Non-invasive Diagnosis of Pulmonary Embolism by Use of Biomarkers in Exhaled Breath Condensate nanCOMPLETED
External Nitric Oxide Measurement Through SNO Degradation nanENROLLING_BY_INVITATION
Exhaled Nitric Oxide : Biomarker of Acute Respiratory Distress Syndrome nanCOMPLETED
Rheo-Erythrocrine Dysfunction as a Biomarker for RIC Treatment in Acute Ischemic Stroke nanCOMPLETED
A Patient-tailored Genetic/Biomarker/iPSC Combined Approach in ALS - PERMEALS nanRECRUITING
When the Kidney Reacts to Nutritional Changes nanCOMPLETED
Specificity of Elevated Plasma EM66 Levels in Pheochromocytoma nanCOMPLETED
Evaluation of ENPP1 Expression and Immune Response in Bladder Cancer Patients nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a ENO1 binder may also engage these)

ProteinNameSimilarity
Q4R5L2 1.000 Q4R5L2 →
P51913 1.000 P51913 →
Q5R6Y1 1.000 Q5R6Y1 →
P19140 1.000 P19140 →
Q9W7L0 1.000 Q9W7L0 →
P13929 1.000 P13929 →
Q9PVK2 1.000 Q9PVK2 →
B5DGQ7 1.000 B5DGQ7 →
P17182 1.000 P17182 →
P04764 1.000 P04764 →
Q3ZC09 1.000 Q3ZC09 →
Q9XSJ4 1.000 Q9XSJ4 →
Q3ZX11 1.000 Q3ZX11 →
I0J1J1 1.000 I0J1J1 →
Q9W7L1 1.000 Q9W7L1 →
Q9W7L2 1.000 Q9W7L2 →
Q1KYT0 1.000 Q1KYT0 →
P26300 1.000 P26300 →
P42040 1.000 P42040 →
P42897 1.000 P42897 →
P21550 1.000 P21550 →
A6L3M9 1.000 A6L3M9 →
P56252 1.000 P56252 →
P15429 1.000 P15429 →
Q9LEJ0 1.000 Q9LEJ0 →
P08734 1.000 P08734 →
A1S4D7 1.000 A1S4D7 →
W7JLR6 1.000 W7JLR6 →
A9NF93 1.000 A9NF93 →
Q12PZ4 1.000 Q12PZ4 →