Sugi Predict

Sugi Predict / Targets / ERG28

ERG28

Ergosterol biosynthetic protein 28 homolog · Q9UKR5 · ERG28 on Sugi Atlas →

0 patent compounds predicted against ERG28, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to ERG28 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
LDL Receptor Under Ezetimibe and Simvastatin PHASE4COMPLETED
Ketoconazole Gel Versus Terconazole Cream for Vaginal Candidiasis PHASE3UNKNOWN
Combination Treatment of 5% Natamycin and 1% Voriconazole in Fungal Keratitis PHASE2/PHASE3UNKNOWN
An Open Label, Non-Comparative, Multicenter, Phase III Trial of the Efficacy, Safety and Toleration of Voriconazole in the Primary or Secondary Treatment of Invasive Fungal Infections PHASE3COMPLETED
Dose-Ranging Study for Miconazole Oil for Treatment of Otomycosis PHASE2COMPLETED
Nebulized Amphotericin B Lipid Complex in Invasive Pulmonary Aspergillosis in Paediatric Patients With Acute Leukaemia PHASE2COMPLETED
Liposomal Amphotericin B (Ambisome) Versus Oral Voriconazole for the Prevention of Invasive Fungal Infections PHASE2COMPLETED
Pharmacokinetics of Anidulafungin (Ecalta ®) Intravenous Given to Patients at High Risk for Developing Invasive Fungal Disease PHASE2COMPLETED
Smith-Lemli-Opitz Syndrome and Cholic Acid PHASE1/PHASE2COMPLETED
A Study on the Tolerability and Early Efficacy of hLF1-11 in Patients With Proven Candidaemia PHASE1/PHASE2WITHDRAWN
A Trial Involving Treatment of BB2603 in Subjects With Distal Subungual Onychomycosis of the Toenail PHASE2COMPLETED
Efficacy and Safety of Drug Combination Therapy of Isotretinoin and Some Antifungal Drugs as A Potential Aerosol Therapy for COVID-19 : An Innovative Therapeutic Approach COVID-19 PHASE2UNKNOWN
SCH-58235 (Ezetimibe) to Treat Homozygous Sitosterolemia PHASE2COMPLETED
NEO100 and High-Grade Meningioma PHASE2RECRUITING
Phase II Study of Simvastatin Plus Irinotecan, Fluorouracil, and Leucovorin(FOLFIRI) for Metastatic CRC PHASE2COMPLETED
Comparison of Efficacy of Single Oral Dose Fluconazole and Itraconazole in Patients With Pityriasis Versicolor PHASE1COMPLETED
F901318 Multiple Ascending Dose Study PHASE1COMPLETED
Epidemiological and Molecular Analysis of Scalp Ringworm in France nanCOMPLETED
Fungal Infections in Patients With Hematological Malignancies nanUNKNOWN
Genetic Study of Sitosterolemia nanCOMPLETED
Elucidating the Molecular and Biochemical Basis of the Human AhR-mutation Disease nanUNKNOWN
The Effect of Dietary Sitosterol on Blood Sugar and Cholesterol nanCOMPLETED
Azole Susceptibility and Resistance Mechanisms Surveys in Pathogenic Fungi by the CARST-fungi (2023-2024) nanNOT_YET_RECRUITING
Correlation Between Circulating Galactomannan and Beta-D-glucan and Clinical Outcome of Invasive Aspergillosis nanUNKNOWN
Early Molecular Detection for the Improved Diagnosis of Invasive Pulmonary Aspergillosis and Invasive Pulmonary Zygomycosis nanCOMPLETED
Efflux Pump Mediated Azole Resistance in Candida Albicans nanUNKNOWN
Exome Sequencing in Autistic Spectrum Disorder nanCOMPLETED
Cholecalciferol for Vitamin D in Adult Cystic Fibrosis (CF) Patients nanCOMPLETED
Fungal Infection Susceptibility nanRECRUITING
Non-invasive Diagnosis of Invasive Pulmonary Aspergillosis by Use of Biomarkers in Exhaled Breath Condensate nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a ERG28 binder may also engage these)

ProteinNameSimilarity
Q9ERY9 — 1.000 Q9ERY9 →
Q5R589 — 1.000 Q5R589 →
A6QQ59 — 0.953 A6QQ59 →
KRTCAP2 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit KCP2 0.950 landscape →
Q5RL79 — 0.949 Q5RL79 →
B2RZC9 — 0.949 B2RZC9 →
P86229 — 0.948 P86229 →
Q8VDI9 — 0.939 Q8VDI9 →
Q9CY27 — 0.937 Q9CY27 →
Q8BWB6 — 0.934 Q8BWB6 →
Q8TD22 — 0.933 Q8TD22 →
Q64232 — 0.933 Q64232 →
Q9H6U8 — 0.932 Q9H6U8 →
TECR Very-long-chain enoyl-CoA reductase 0.931 landscape →
Q3ZCD7 — 0.931 Q3ZCD7 →
Q8CFD0 — 0.928 Q8CFD0 →
Q925N0 — 0.928 Q925N0 →
A6NI61 — 0.927 A6NI61 →
D0Q0Y7 — 0.926 D0Q0Y7 →
Q8IZV2 — 0.926 Q8IZV2 →
Q2TA01 — 0.925 Q2TA01 →
Q8NFT2 — 0.925 Q8NFT2 →
Q9D8B1 — 0.920 Q9D8B1 →
Q1RMP9 — 0.920 Q1RMP9 →
B2KI79 — 0.920 B2KI79 →
Q6ZWS4 — 0.917 Q6ZWS4 →
Q8TBE1 — 0.917 Q8TBE1 →
Q6ZVK1 — 0.917 Q6ZVK1 →
Q3KNM2 — 0.917 Q3KNM2 →
Q0X0A5 — 0.917 Q0X0A5 →