ESYT1

Extended synaptotagmin-1 · Q9BSJ8 · ESYT1 on Sugi Atlas →

0 patent compounds predicted against ESYT1, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to ESYT1 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Prehospital Early Administration of Ketamine for Status Epilepticus in Epileptic Kids (PEAK-SEEK) PHASE2/PHASE3RECRUITING
Comparison Between Botox and Magnesium Sulfate Effect in Treatment of Myofascial Pain Trigger Points Within the Masseter Muscle PHASE2/PHASE3NOT_YET_RECRUITING
Efficacy and Safety of Endoxifen in Bipolar I Disorder Patients PHASE3ACTIVE_NOT_RECRUITING
Dronabinol in Trichotillomania and Other Body Focused Repetitive Behaviors PHASE2/PHASE3COMPLETED
Assess Safety and Efficacy of Sovateltide in Hypoxic-ischemic Encephalopathy PHASE2RECRUITING
Treatment of Temporo-Myofascial Disorder of Muscular Origin Using Botulinum Toxin: A Prospective Study PHASE2UNKNOWN
The Synapse Project PHASE2COMPLETED
Dose Escalation Study of Immunomodulatory Nanoparticles PHASE1ACTIVE_NOT_RECRUITING
Nilotinib in Huntington's Disease PHASE1UNKNOWN
Phenylbutyrate for Monogenetic Developmental and Epileptic Encephalopathy EARLY_PHASE1ACTIVE_NOT_RECRUITING
Dynamics of Muscle Mitochondria in Type 2 Diabetes (DYNAMMO T2D) EARLY_PHASE1COMPLETED
Comparing Outcomes of Theta Burst Stimulation in Depression Using Advanced PET Imaging nanNOT_YET_RECRUITING
Baker Gordon Syndrome Natural History Study nanRECRUITING
Transcriptomic Profile of Patients Treated With Different Modalities of Spinal Cord Stimulation nanUNKNOWN
STXBP1 and SYNGAP1 Related Disorders Natural History Study nanRECRUITING
Protein Synthesis in the Brain of Patients With Fragile X Syndrome nanCOMPLETED
Investigating Phenotypic, Epigenetic, and NeuroGenetic Traits in Rare and Ultra-rare Neurodevelopmental Disorders (Project PENGUIN) nanRECRUITING
Gene-STEPS: Shortening Time of Evaluation in Paediatric Epilepsy Services nanUNKNOWN
Relationship of Gestational Age and Urine Concentration of S100B in Preterm and Term Infants in the First Week of Life nanCOMPLETED
Study of the Genetic Factors Involved in Autism and Related Disorders nanRECRUITING
A Study on Risk Mutations of Vulnerability Genes of Schizophrenia nanUNKNOWN
Intra-cortical Inhibition and Cognitive Deficits in Schizophrenia nanUNKNOWN
The Influence of Genetic Variations in ELAPOR1 or ELAPOR2 on Insulin Secretion and Glucose Regulation in Humans nanUNKNOWN
miR-142-3p as Potential Biomarker of Synaptopathy in MS nanUNKNOWN
Dynamics of Muscle Mitochondria in Type 2 Diabetes Exercise nanCOMPLETED
Genes, Proteins, and Metabolites in Drug-resistant Epilepsy (DRE) Patients nanNOT_YET_RECRUITING
Natural History Study of SLC25A46 Mutation-related Mitochondriopathy nanCOMPLETED
Urine Concentration of S100B in Extremely Premature Infants nanCOMPLETED
A Study on Psychopathological Progress of Early Schizophrenia-Like Disorder (SOPRES) nanUNKNOWN
Novel Strategy for Early Detection of Esophageal Squamous Cell Carcinoma nanRECRUITING

Related proteins — ESM-2 sequence neighbours (a ESYT1 binder may also engage these)

ProteinNameSimilarity
Q5RAG2 1.000 Q5RAG2 →
Q9Z1X1 1.000 Q9Z1X1 →
Q3U7R1 0.997 Q3U7R1 →
Q3TZZ7 0.992 Q3TZZ7 →
ESYT2 Extended synaptotagmin-2 0.978 landscape →
Q9Z268 0.978 Q9Z268 →
MAP4K2 Mitogen-activated protein kinase kinase kinase kinase 2 0.976 landscape →
Q6PFQ7 0.974 Q6PFQ7 →
P70268 0.973 P70268 →
PKN1 Serine/threonine-protein kinase N1 0.972 landscape →
Q8K045 0.972 Q8K045 →
Q61161 0.971 Q61161 →
O43374 0.971 O43374 →
A1A4I4 0.971 A1A4I4 →
Q3UFQ8 0.971 Q3UFQ8 →
C9J798 0.970 C9J798 →
B2RUP2 0.970 B2RUP2 →
O95294 0.970 O95294 →
Q5XHY1 0.969 Q5XHY1 →
Q70J99 0.969 Q70J99 →
PKN3 Serine/threonine-protein kinase N3 0.968 landscape →
Q8ND23 0.968 Q8ND23 →
Q6V7V2 0.967 Q6V7V2 →
P47861 0.967 P47861 →
Q8BY35 0.967 Q8BY35 →
Q8K2J0 0.967 Q8K2J0 →
Q63433 0.966 Q63433 →
Q9UBL6 0.965 Q9UBL6 →
Q9BST9 0.964 Q9BST9 →
Q8N3E9 0.962 Q8N3E9 →