Sugi Predict

Sugi Predict / Targets / EXOSC5

EXOSC5

Exosome complex component RRP46 · Q9NQT4 · EXOSC5 on Sugi Atlas →

0 patent compounds predicted against EXOSC5, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to EXOSC5 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Melpida: Recombinant Adeno-associated Virus (serotype 9) Encoding a Codon Optimized Human AP4M1 Transgene (hAP4M1opt) PHASE1/PHASE2RECRUITING
Effect of PAE Hydrogel Loaded With tRF-ASO-Exo on Patients With Diabetic Ocular Surface Diseases PHASE2NOT_YET_RECRUITING
Intra-discal Injection of Platelet-rich Plasma (PRP) Enriched With Exosomes in Chronic Low Back Pain PHASE1COMPLETED
Ovarian Rejuvenation Using Platelet Rich Plasma (PRP) & Autologous Tissue Stromal Vascular Fraction (tSVF) and Cell Enriched tSVF PHASE1UNKNOWN
A Clinical Study on Safety and Effectiveness of Mesenchymal Stem Cell Exosomes for the Treatment of COVID-19. EARLY_PHASE1UNKNOWN
Cell Free Circulating Nucleic Acids as New Tumor Diagnostics From Human Plasma Samples. nanUNKNOWN
A Study That Collects Participant Data and Biospecimens to Analyze Pathogenic Exosomes That Mediate Increased Vascular Dementia Risk in Individuals With Herpes Zoster. nanRECRUITING
B3 for NMD: Bench to Bedside and Back nanENROLLING_BY_INVITATION
Identification of New Diagnostic Protein Markers for Colorectal Cancer nanCOMPLETED
Exosomal microRNAs as a Biomarker in Panic Disorder and in Response to CBT nanUNKNOWN
A Randomized Trial of Intratympanic Drug Delivery: Evaluating the Efficacy and Safety of Dexamethasone-Loaded Exosomes Versus Standard Therapy in Acute Sensorineural Hearing Loss. nanRECRUITING
Exosomes Proteomic for Sjogren's Syndrome and Dry Eye Syndrome nanRECRUITING
Study of Exosomes in Monitoring Patients With Sarcoma (EXOSARC) nanCOMPLETED
Exosome of Mesenchymal Stem Cells for Multiple Organ Dysfuntion Syndrome After Surgical Repaire of Acute Type A Aortic Dissection nanNOT_YET_RECRUITING
LINC00511/miR-185-3p Axis and miR-301a-3p Markers for Breast Cancer Diagnosis nanCOMPLETED
Improving Sleep, Sleep-related Outcomes, and Biomarkers in Veterans nanACTIVE_NOT_RECRUITING
Exosome-based Liquid Biopsies for Upper Gastrointestinal Cancers Diagnosis nanUNKNOWN
Micro RNAs to Predict Response to Androgen Deprivation Therapy nanCOMPLETED
A Study of Circulating Exosome Proteomics In Gallbladder Carcinoma Patients nanUNKNOWN
New Biomarkers in Pancreatic Cancer Using EXPEL Concept nanRECRUITING
Pancreatic Cancer Detection Consortium nanRECRUITING
Pilot Study of Microvesicles in Pre-eclamptic and Non-pre-eclamptic Women With Threatened Preterm Delivery nanRECRUITING
Studying The Role of Key Epigenetic Mediators in Breast Cancer Patients nanRECRUITING
Performance Determinants Factors in Elite Endurance Athletes. nanCOMPLETED
Detection of Circulating Biomarkers of Immunogenic Cell Death nanCOMPLETED
Expression and Clinical Significance of IGHD in Pancreatic Cancer nanUNKNOWN
Research on the Early and Prognosis Diagnosis of Vascular Dementia nanRECRUITING
Investigating the Role of Biomarkers in Predicting Outcome for COVID 19 nanUNKNOWN
When the Kidney Reacts to Nutritional Changes nanCOMPLETED
Improving the Early Detection of Lung Cancer by Combining Exosomal Analysis of Hypoxia With Standard of Care Imaging nanUNKNOWN

Related proteins — ESM-2 sequence neighbours (a EXOSC5 binder may also engage these)

ProteinNameSimilarity
Q9CRA8 — 0.998 Q9CRA8 →
Q921I9 — 0.954 Q921I9 →
Q5RCW2 — 0.949 Q5RCW2 →
Q7YRA3 — 0.947 Q7YRA3 →
Q8TCS8 — 0.946 Q8TCS8 →
Q8K1R3 — 0.946 Q8K1R3 →
Q9D753 — 0.943 Q9D753 →
P0CL18 — 0.943 P0CL18 →
EXOSC4 Exosome complex component RRP41 0.943 landscape →
Q5E9T8 — 0.942 Q5E9T8 →
Q5PPG7 — 0.942 Q5PPG7 →
P41214 — 0.941 P41214 →
Q5RA63 — 0.941 Q5RA63 →
Q2KHU3 — 0.940 Q2KHU3 →
Q3SZD4 — 0.938 Q3SZD4 →
Q58CR3 — 0.938 Q58CR3 →
Q9BV38 — 0.938 Q9BV38 →
A2RVK7 — 0.937 A2RVK7 →
Q03426 — 0.937 Q03426 →
Q9QYM7 — 0.936 Q9QYM7 →
ERCC4 DNA repair endonuclease XPF (EC 3.1.-.-) (DNA 0.935 landscape →
O70422 — 0.935 O70422 →
Q9D0M0 — 0.934 Q9D0M0 →
P17256 — 0.934 P17256 →
Q96B26 — 0.933 Q96B26 →
P60027 — 0.933 P60027 →
Q8BNV1 — 0.933 Q8BNV1 →
O43818 — 0.933 O43818 →
Q61211 — 0.933 Q61211 →
Q91W86 — 0.932 Q91W86 →