FAHD1

Oxaloacetate tautomerase FAHD1, mitochondrial · Q6P587 · FAHD1 on Sugi Atlas →

3,340 patent compounds predicted against FAHD1, 2,338 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
Oxalic Acid (SCHEMBL222911)	0.89	1/20
Oxalic Acid (SCHEMBL471849)	0.89	1/20
Oxalic Acid (SCHEMBL694299)	0.89	1/20
Oxalic Acid (SCHEMBL3202744)	0.89	1/20
Oxalic Acid (SCHEMBL48467)	0.78	1/20
Oxalic Acid (SCHEMBL79869)	0.78	1/20
Oxalic Acid (SCHEMBL93229)	0.78	1/20
Oxalic Acid (SCHEMBL133099)	0.78	1/20
Oxalic Acid (SCHEMBL136988)	0.78	1/20
Oxalic Acid (SCHEMBL140306)	0.78	1/20
Oxalic Acid (SCHEMBL140307)	0.78	1/20
Oxalic Acid (SCHEMBL141462)	0.78	1/20
Oxalic Acid (SCHEMBL153033)	0.78	1/20
Oxalic Acid (SCHEMBL171434)	0.78	1/20
Oxalic Acid (SCHEMBL171435)	0.78	1/20
Oxalic Acid (SCHEMBL187302)	0.78	1/20
Oxalic Acid (SCHEMBL191688)	0.78	1/20
Oxalic Acid (SCHEMBL193638)	0.78	1/20
Oxalic Acid (SCHEMBL193975)	0.78	1/20
Oxalic Acid (SCHEMBL234978)	0.78	1/20

Clinical trials — most relevant to FAHD1 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Evaluation of the Effects of Calcitriol's in the Neurological Symptoms of Friedreich's Ataxia Patients	PHASE4	COMPLETED
A Study of the Efficacy and Safety of MT1621 in Thymidine Kinase 2 (TK2) Deficiency (Treatment naïve)	PHASE3	WITHDRAWN
Trial of Dichloroacetate in Pyruvate Dehydrogenase Complex Deficiency:	PHASE3	ACTIVE_NOT_RECRUITING
A Study of Bezafibrate in Mitochondrial Myopathy	PHASE2	COMPLETED
A Pilot Clinical Trial With the Iron Chelator Deferiprone in Parkinson's Disease	PHASE2	COMPLETED
Doxecitin and Doxribthymine in Adult Subjects With Thymidine Kinase 2 (TK2) Deficiency	PHASE2	RECRUITING
Methylprednisolone Treatment of Friedreich Ataxia	EARLY_PHASE1	COMPLETED
Fatty Acid Oxidation Defects and Insulin Sensitivity	nan	COMPLETED
Tissue Sample Study for Mitochondrial Disorders	nan	ENROLLING_BY_INVITATION
Biomarker for the Early Diagnosis and Monitoring in Tyrosinemia Type 1 (BioTyrosin)	nan	WITHDRAWN
North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC)	nan	RECRUITING
Natural History and Advanced Genetic Study of Pyruvate Dehydrogenase Complex Deficiencies	nan	RECRUITING
Compassionate Use of Triheptanoin (C7) for Inherited Disorders of Energy Metabolism	nan	NO_LONGER_AVAILABLE
MRI Study - Chronic Progressive External Ophthalmoplegia	nan	COMPLETED
Clinical Study of Hydroxytyrosol (HT) in Mitochondrial Diseases	nan	COMPLETED
GDF-15 as a Biomarker for Mitochondrial Disease	nan	COMPLETED
The Genetics of Diabetes in Southern California Chinese Americans	nan	WITHDRAWN
Identification of New Candidate Genes in Patients With Mitochondrial Disease by High Resolution Chromosome Analysis on DNA Chip	nan	COMPLETED
Nicotinamide Riboside and Mitochondrial Biogenesis	nan	COMPLETED
MITOMICS : a Multi-OMICS Approach for the Diagnosis of Mitochondrial Diseases	nan	RECRUITING
The Natural History of Mitochondrial Diseases	nan	RECRUITING
Genomic Profiling of Mitochondrial Disease - Imaging Analysis for Precise Mitochondrial Medicine	nan	COMPLETED
Cardiac Manifestation and Inherited Metabolic Diseases	nan	COMPLETED
Glycine and Magnesium+Thiamine for the Treatment of Primary Ciliary Dyskinesia	nan	RECRUITING
Natural History Study of FDXR Mutation-related Mitochondriopathy	nan	COMPLETED
Pathogenic Insights and Search for Biomarkers in RFC1-ataxia/CANVAS	nan	RECRUITING
Pattern of Metabolic Causes of Neonatal Hypoglycemia	nan	UNKNOWN
Mitochondrial Dysfunctions Driving Insulin Resistance	nan	COMPLETED
Genetic and Metabolic Disease in Children	nan	RECRUITING
Drug Repurposing for Mitochondrial Disorders Using iPSCs Derived Neural Cells	nan	RECRUITING

Related proteins — ESM-2 sequence neighbours (a FAHD1 binder may also engage these)

Protein	Name	Similarity
Q2HJ98	—	1.000	Q2HJ98 →
Q5RDW0	—	1.000	Q5RDW0 →
Q6AYQ8	—	0.996	Q6AYQ8 →
Q8R0F8	—	0.992	Q8R0F8 →
Q93ZE5	—	0.992	Q93ZE5 →
Q10B63	—	0.987	Q10B63 →
Q9LUR3	—	0.984	Q9LUR3 →
A3AJ77	—	0.981	A3AJ77 →
Q9P7L4	—	0.980	Q9P7L4 →
P34673	—	0.979	P34673 →
B2RYW9	—	0.976	B2RYW9 →
Q5RCX5	—	0.973	Q5RCX5 →
O86042	—	0.973	O86042 →
Q3TC72	—	0.973	Q3TC72 →
Q9RPU5	—	0.973	Q9RPU5 →
F1MLX0	—	0.972	F1MLX0 →
Q86I22	—	0.971	Q86I22 →
P76004	—	0.969	P76004 →
Q2KIB0	—	0.968	Q2KIB0 →
Q6GLT8	—	0.968	Q6GLT8 →
Q96GK7	—	0.967	Q96GK7 →
Q0QFQ3	—	0.967	Q0QFQ3 →
Q46978	—	0.967	Q46978 →
Q6P2I3	—	0.966	Q6P2I3 →
P53889	—	0.966	P53889 →
Q1BJJ1	—	0.965	Q1BJJ1 →
P37352	—	0.964	P37352 →
O28058	—	0.962	O28058 →
Q1NEI7	—	0.962	Q1NEI7 →
O06724	—	0.960	O06724 →