FASTKD1

FAST kinase domain-containing protein 1, mitochondrial · Q53R41 · FASTKD1 on Sugi Atlas →

0 patent compounds predicted against FASTKD1, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to FASTKD1 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Metformin Use to Reduce Disparities in Newly Diagnosed Breast Cancer PHASE4WITHDRAWN
A Study of the Efficacy and Safety of MT1621 in Thymidine Kinase 2 (TK2) Deficiency (Treatment naïve) PHASE3WITHDRAWN
Clinical Evaluation of the Effect of Metformin in Sepsis PHASE3UNKNOWN
Use of New Drug QRX-3 for Prevention and Treatment of Chronic Kidney Disease Progression PHASE2/PHASE3NOT_YET_RECRUITING
Bezafibrate Trial in CPT2 Deficiency PHASE3UNKNOWN
Doxecitin and Doxribthymine in Adult Subjects With Thymidine Kinase 2 (TK2) Deficiency PHASE2RECRUITING
Bempedoic Acid Therapy for Polycystic Kidney Disease PHASE2NOT_YET_RECRUITING
Dynamics of Muscle Mitochondria in Type 2 Diabetes (DYNAMMO T2D) EARLY_PHASE1COMPLETED
Effects of a Very Low Carbohydrate Ketogenic Diet or Mediterranean Diet on Markers of Musculoskeletal Health in Older Adults nanCOMPLETED
Skeletal Muscle Regeneration in Survivors of Critical Illness: How to Prevent Satellite Cell Failure? nanRECRUITING
Metabolic Therapy Program In Conjunction With Standard Treatment For Glioblastoma nanCOMPLETED
Measuring Protein Turnover in Humans Across the Lifespan by Metabolic Labeling With Deuterium Oxide nanRECRUITING
Mitochondrial Dysfunction in Phelan-McDermid Syndrome nanCOMPLETED
Mechanisms of the Effect of Physical Activity on the Adaptation to a High-Fat Diet nanCOMPLETED
Dynamics of Muscle Mitochondria in Type 2 Diabetes Exercise nanCOMPLETED
Time Restricted Feeding in Autosomal Dominant Polycystic Kidney Disease nanCOMPLETED
Relationship Between Mitochondrial Dysfunction and Fatique in Cancer Patients Following External Beam Radiation Therapy nanCOMPLETED
Mitochondrial Function in the Peri-operative Setting: an Observational Study nanNOT_YET_RECRUITING
Whey Protein Support to Metabolic and Performance Adaptations in Response HIIT nanCOMPLETED
Ketogenic Diet and Prostate Cancer Surveillance Pilot nanCOMPLETED
Diagnostic Odyssey Survey 2 nanCOMPLETED
Transgenerational Metabolic-Immune Biomarkers of Neurological and Neurodevelopmental Disorders nanRECRUITING
Abnormalities in the Effects of Insulin and Exercise on Glucose- and Lipid Metabolism in Obesity and Type 2 Diabetes nanCOMPLETED
Molecular Pathways Related to Short-term Fasting Response nanCOMPLETED
Effect of Branched Chain Amino Acids on Muscle nanCOMPLETED
McArdle Disease Treatment by Ketogenic Diet nanCOMPLETED
Insulin Deprivation on Brain Structure and Function in Humans With Type 1 Diabetes nanCOMPLETED
Nicotinamide Riboside and Mitochondrial Biogenesis nanCOMPLETED
Effects of Acute Energy Deficit and Aerobic Exercise on Muscle Quality nanCOMPLETED
North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC) nanRECRUITING

Related proteins — ESM-2 sequence neighbours (a FASTKD1 binder may also engage these)

ProteinNameSimilarity
Q6GQ66 1.000 Q6GQ66 →
Q6DI86 1.000 Q6DI86 →
Q14CZ7 0.998 Q14CZ7 →
Q28DE0 0.996 Q28DE0 →
Q68FN9 0.995 Q68FN9 →
Q6PA48 0.994 Q6PA48 →
Q58CX2 0.994 Q58CX2 →
FASTKD5 FAST kinase domain-containing protein 5, mitochondrial 0.993 landscape →
Q95KD0 0.993 Q95KD0 →
Q14C51 0.991 Q14C51 →
Q5RFI6 0.990 Q5RFI6 →
Q5R8W8 0.989 Q5R8W8 →
Q8BSN9 0.989 Q8BSN9 →
Q6DJ55 0.988 Q6DJ55 →
Q32LU7 0.988 Q32LU7 →
Q6PB66 0.987 Q6PB66 →
Q008S8 0.986 Q008S8 →
Q09YH1 0.986 Q09YH1 →
Q8VD46 0.985 Q8VD46 →
Q2KI62 0.985 Q2KI62 →
Q2IBF5 0.985 Q2IBF5 →
Q09YK6 0.985 Q09YK6 →
Q7TMV3 0.985 Q7TMV3 →
O15091 0.985 O15091 →
LRPPRC Leucine-rich PPR motif-containing protein, mitochondrial 0.985 landscape →
Q09YN0 0.985 Q09YN0 →
PTCD3 Small ribosomal subunit protein mS39 0.985 landscape →
Q3SZ55 0.984 Q3SZ55 →
Q80ZJ6 0.984 Q80ZJ6 →
Q80YE7 0.984 Q80YE7 →