FLNA — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

	Compound	Confidence	Supporting neighbours

Clinical trials — most relevant to FLNA by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Safety and Tolerability of Lacosamide in Patients With Gain-of-function Nav1.7 Mutations Related Small Fiber Neuropathy	PHASE3	COMPLETED
Treatment of Ectopic Calcification in Fahr's Disease or Syndrome	PHASE2	RECRUITING
The Impact of Botox on Neuroimmune Interactions in Atopic Dermatitis	PHASE1	RECRUITING
Bone Marrow Cell Gene Transfer in Individuals With Fanconi Anemia	PHASE1	COMPLETED
Atopic Dermatitis in Atopy Predisposed Infants	nan	COMPLETED
18F-FDG PET/TC in TIR3A e TIR3B	nan	ENROLLING_BY_INVITATION
Molecular Analysis of Patients With Neuromuscular Disease	nan	RECRUITING
Genetic Analysis of Fraser Syndrome and Fryns Syndrome	nan	COMPLETED
Application of Linkage Analysis in the Identification of Novel Hereditary Factors in Familial Aneurysms	nan	ACTIVE_NOT_RECRUITING
Genetic Bases of Neuroendocrine Neoplasms in Mexican Patients	nan	RECRUITING
Corrective Exercise and Rehabilitation in Fanconi Anemia: A Case Study	nan	COMPLETED
CTHRC1: A Biomarker for Evaluation of Rheumatoid Arthritis Disease Activity	nan	UNKNOWN
Natural History of Autosomal Dominant Hearing Loss	nan	RECRUITING
Circulating Markers for Ischemic Heart Disease	nan	RECRUITING
Signs and Symptoms Associated With Molecular Defects in Genetically Inherited Heart Disease	nan	COMPLETED
Genetic Markers for Focal Segmental Glomerulosclerosis	nan	COMPLETED
Genetics of Fibromyalgia	nan	UNKNOWN
Nerve Ultrasound in Acquired and Genetic Sensory Neuronopathies	nan	NOT_YET_RECRUITING
Muscle Tissue Bank for Muscular Dystrophy	nan	COMPLETED
FA Clinical Outcome Measures	nan	ACTIVE_NOT_RECRUITING
Characterization of New Candidate Genes in Cases of Human Inherited Thrombocytopenia (CATCH)	nan	COMPLETED
Frequency of SOD1 and C9orf72 Gene Mutations in French ALS	nan	COMPLETED
Clinical Outcome Study for Dysferlinopathy	nan	UNKNOWN
Circulating Markers That Underlie the Transition From Compensated Hypertrophy to Heart Failure	nan	RECRUITING
Genotype-phenotype Correlation in Junctional Epidermolysis Bullosa	nan	UNKNOWN
Role of Genetics in Idiopathic Pulmonary Fibrosis (IPF)	nan	UNKNOWN
Familial Intracranial Aneurysm Study II	nan	COMPLETED
Prospective Multicenter Study on the Identification of Genetic Abnormalities Predisposing to Vasospasm From a Privileged Model: the Primary Raynaud's Phenomenon	nan	COMPLETED
Neurorehabilitation in Patients With Disorders of Consciousness: Multidimensional Ambispective Study on the Impact of Single and Combined Approaches	nan	RECRUITING
Friedreich Ataxia Global Clinical Consortium UNIFIED Natural History Study	nan	RECRUITING

Related proteins — ESM-2 sequence neighbours (a FLNA binder may also engage these)

Protein	Name	Similarity
Q8BTM8	—	1.000	Q8BTM8 →
Q8VHX6	—	1.000	Q8VHX6 →
Q14315	—	0.999	Q14315 →
Q80X90	—	0.997	Q80X90 →
D3ZHA0	—	0.996	D3ZHA0 →
FLNB	Filamin-B	0.995	landscape →
Q9VEN1	—	0.989	Q9VEN1 →
P13466	—	0.979	P13466 →
Q61233	—	0.974	Q61233 →
LCP1	Plastin-2	0.972	landscape →
Q6P698	—	0.972	Q6P698 →
Q99K51	—	0.972	Q99K51 →
Q32PH8	—	0.971	Q32PH8 →
P62631	—	0.971	P62631 →
P31669	—	0.971	P31669 →
O08688	—	0.971	O08688 →
Q63598	—	0.971	Q63598 →
Q92178	—	0.971	Q92178 →
P16638	—	0.970	P16638 →
P16081	—	0.970	P16081 →
P00789	—	0.970	P00789 →
P50256	—	0.970	P50256 →
Q9ZNT0	—	0.970	Q9ZNT0 →
Q5RAZ4	—	0.970	Q5RAZ4 →
Q941L3	—	0.970	Q941L3 →
A7E3Q8	—	0.970	A7E3Q8 →
A0A286R227	—	0.970	A0A286R227 →
Q07009	—	0.970	Q07009 →
Q8K009	—	0.970	Q8K009 →
O94489	—	0.970	O94489 →