FN1

Fibronectin · P02751 · FN1 on Sugi Atlas →

50 patent compounds predicted against FN1, 23 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL14421357 SCHEMBL14421357 0.77 4/20
SCHEMBL13046704 SCHEMBL13046704 0.71 4/20
SCHEMBL14279932 SCHEMBL14279932 0.68 4/20
SCHEMBL14279940 SCHEMBL14279940 0.68 4/20
SCHEMBL13046700 SCHEMBL13046700 0.65 4/20
SCHEMBL14279946 SCHEMBL14279946 0.65 4/20
SCHEMBL14421326 SCHEMBL14421326 0.60 4/20
SCHEMBL14279951 SCHEMBL14279951 0.54 4/20
SCHEMBL14587051 SCHEMBL14587051 0.52 4/20
SCHEMBL16144717 SCHEMBL16144717 0.51 4/20
SCHEMBL15848778 SCHEMBL15848778 0.64 3/20
SCHEMBL14342409 SCHEMBL14342409 0.63 3/20
SCHEMBL15848776 SCHEMBL15848776 0.55 3/20
SCHEMBL14172588 SCHEMBL14172588 0.54 3/20
SCHEMBL15848764 SCHEMBL15848764 0.52 3/20
SCHEMBL15848914 SCHEMBL15848914 0.51 3/20
SCHEMBL14342382 SCHEMBL14342382 0.50 3/20
SCHEMBL14342410 SCHEMBL14342410 0.49 3/20
SCHEMBL13046711 SCHEMBL13046711 0.38 3/20
SCHEMBL15848769 SCHEMBL15848769 0.52 1/20

Clinical trials — most relevant to FN1 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Comparing the Effects of Spironolactone With Chlortalidone on LV Mass in Patients With CKD PHASE4UNKNOWN
Arthroscopy and Manipulation vs a Home Therapy Program in the Treatment of Adhesive Capsulitis PHASE4COMPLETED
Study to Evaluate the Possible Antifibrotic Effect of Zinc Sulphate in Chronic HCV Patient Receiving Direct Acting Anti-viral Therapy. PHASE3COMPLETED
A Trial of Tadalafil in Interstitial Lung Disease of Scleroderma PHASE3COMPLETED
Nintedanib in Lung Transplant Recipients With Bronchiolitis Obliterans Syndrome Grade 0p-1-2 PHASE3COMPLETED
Phase I Clinical Study Combining L19-IL2 With SABR in Patients With Oligometastatic Solid Tumor PHASE1COMPLETED
Multi-omics Study of Peritoneal Dialysis Effluent to Explore Biomarkers of Peritoneal Fibrosis nanNOT_YET_RECRUITING
Pathology, Venous Disease, and Clinical Correlations nanUNKNOWN
Study of HLA-DR in Cell Cultures Isolated From Primary Squamous Cell Carcinoma nanUNKNOWN
Tracking the Natural Course of Silent Small Bowel Narrowing in Adults With Crohn's Disease nanCOMPLETED
Prospective Monocentric Clinical-biological Database nanRECRUITING
Evaluation of Irisin Levels in Adult Forearm Fracture Surgery Under Infraclavicular Block and General Anesthesia nanNOT_YET_RECRUITING
Clinical and Genetic Studies in Familial Non-medullary Thyroid Cancer nanRECRUITING
Fetal Fibronectin as a Predictor of Successful Induction of Mid-trimester Abortion nanCOMPLETED
Biomarkers in the Diagnosis and Prognosis of NAFLD nanRECRUITING
Role of Nox2 in CNI-induced Renal Fibrosis nanCOMPLETED
Clinical Study on the Application of PET Probes Targeting DDR2 in the Diagnosis of Interstitial Lung Disease With Cognitive Impairment nanNOT_YET_RECRUITING
Vascular Function, Sarcopenia and Pain in Postmenopausal Osteoporosis nanRECRUITING
Clinical and Basic Research on the Necessity of Scar Tissue Resection During Intrauterine Adhesions nanUNKNOWN
Pharmacogenomics of Interferon and Ribavirin Treatment in Patients With Chronic Hepatitis C Virus Infection nanUNKNOWN
Dynamic Changes in the Levels of sCD62L and SPARC in Chronic Myeloid Leukemia Patients During Imatinib Treatment nanCOMPLETED
Fibrotic Focus in Breast Cancer nanUNKNOWN
Angiotensin II Antagonism of TGF-Beta 1 nanCOMPLETED
Comparison the Level of CTGF Protein and Related Cytokine in Pleural Effusion nanUNKNOWN
PAINDYS_Characterizing Pain in Fibrous Dysplasia of Bone/McCune-Albright Syndrome: an Exploratory Pilot Study nanNOT_YET_RECRUITING
Ventricular Matrix Remodeling: Correlates and Prognosis nanCOMPLETED
Comparison of Topical Use of Platelet-rich Plasma Versus Hyaluronic Acid During Endoscopic Fat Graft Myringoplasty: a Randomized Clinical Study nanNOT_YET_RECRUITING
The Influence of Daily Grapes Intake on Sarcopenia in Postmenopausal Women nanCOMPLETED
Development of a Wearable Device for Osteoporosis Prevention and Fracture Risk Reduction in Women nanENROLLING_BY_INVITATION
Arterial Composition and Cardiovascular Outcome in DIabeteS nanUNKNOWN

Related proteins — ESM-2 sequence neighbours (a FN1 binder may also engage these)

ProteinNameSimilarity
Q28749 1.000 Q28749 →
P07589 1.000 P07589 →
Q28275 1.000 Q28275 →
Q91740 1.000 Q91740 →
Q28377 0.999 Q28377 →
P04937 0.998 P04937 →
P11276 0.998 P11276 →
P11722 0.997 P11722 →
P14543 0.987 P14543 →
Q91400 0.983 Q91400 →
P10493 0.983 P10493 →
Q7TQN3 0.981 Q7TQN3 →
Q14118 0.981 Q14118 →
Q90344 0.980 Q90344 →
Q66K08 0.980 Q66K08 →
Q80YX1 0.979 Q80YX1 →
O42422 0.979 O42422 →
Q03145 0.979 Q03145 →
PTPRM Receptor-type tyrosine-protein phosphatase mu 0.979 landscape →
O61307 0.979 O61307 →
A0M8R7 0.979 A0M8R7 →
Q94128 0.978 Q94128 →
G4V4G1 0.978 G4V4G1 →
O60687 0.978 O60687 →
A6H737 0.978 A6H737 →
O18016 0.978 O18016 →
Q09YH7 0.978 Q09YH7 →
O77469 0.978 O77469 →
Q98TB4 0.978 Q98TB4 →
P61135 0.978 P61135 →