GAPVD1

GTPase-activating protein and VPS9 domain-containing protein 1 · Q14C86 · GAPVD1 on Sugi Atlas →

0 patent compounds predicted against GAPVD1, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to GAPVD1 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Safety and Efficacy of AAV9/AP4B1 (BFB-101) For Patients With AP4B1-related Hereditary Spastic Paraplegia Type 47 (SPG47) PHASE1/PHASE2NOT_YET_RECRUITING
Pembrolizumab Plus Enfortumab Vedotin in Collecting Duct and Renal Medullary Carcinoma PHASE2RECRUITING
Melpida: Recombinant Adeno-associated Virus (serotype 9) Encoding a Codon Optimized Human AP4M1 Transgene (hAP4M1opt) PHASE1/PHASE2RECRUITING
Simvastatin + Cetuximab/Irinotecan in K-ras Mutant Colorectal Cancer (CRC) PHASE2COMPLETED
Study of the Pathophysiological Mechanisms Involved in Bleeding Events nanCOMPLETED
Investigating Phenotypic, Epigenetic, and NeuroGenetic Traits in Rare and Ultra-rare Neurodevelopmental Disorders (Project PENGUIN) nanRECRUITING
Autophagy in Systemic Lupus Erythematosus nanUNKNOWN
ADRB3, ROCK2 and GEF Levels in Overactive Bladder Patients nanCOMPLETED
Regulation of Lymphocyte Anti-tumor Response in Metastatic Patients Treated With the mTOR Inhibitor Everolimus nanCOMPLETED
The Natural History of the Progression of Atrophy Secondary to Stargardt Disease Type 4: PROM1-Related Macular Dystrophy nanCOMPLETED
Genetic Characterization of Parkinson's Disease nanCOMPLETED
Biomarker Research in Inherited Movement Disorders nanRECRUITING
Registry Gangliosidoses nanUNKNOWN
Natural History Study of GEMIN-5 Related Neurodevelopmental Disorder nanRECRUITING
PHF19 Gene Expression and EZH2 Gene Deletion in Acute Myeloid Leukemia nanUNKNOWN
Long-read Genome Sequencing for the Molecular Diagnosis of Dystonia nanRECRUITING
STXBP1 and SYNGAP1 Related Disorders Natural History Study nanRECRUITING
The Genetic Basis of Inherited Neurologic Deficits in People With Schizophrenia nanCOMPLETED
Avapritinib in the Treatment of Unresectable or Recurrent Metastatic GIST Non-exon18 Mutations of PDGFRA nanRECRUITING
GNAO1 Natural History Study nanUNKNOWN
Chromosome 9 P Minus Syndrome nanRECRUITING
Lymphoid Tyrosine Phosphatase Gene Polymorphisms in Inflammatory Bowel Disease nanUNKNOWN
Classification, Functional Stratification and Biomarkers in Ciliopathy (CILLICORIRCM) nanCOMPLETED
Investigating the Genetic Basis of Pseudoexfoliation Syndrome, Angle-closure Glaucoma and Primary Open-angle Glaucoma nanRECRUITING
Rab 32 Gene Polymorphisms as a Prognostic Factor in Leprosy Patients nanRECRUITING
Neurodevelopmental Outcomes in Hypoplastic Left Heart Syndrome nanCOMPLETED
Clinical and Laboratory Analysis of Familial Cancer nanCOMPLETED
National Cohort on Congenital Defects of the Eye nanRECRUITING
Genetic Studies of Strabismus, Congenital Cranial Dysinnervation Disorders (CCDDs), and Their Associated Anomalies nanRECRUITING
Study of the Genetic Factors Involved in Autism and Related Disorders nanRECRUITING

Related proteins — ESM-2 sequence neighbours (a GAPVD1 binder may also engage these)

ProteinNameSimilarity
A5D794 1.000 A5D794 →
Q6PAR5 1.000 Q6PAR5 →
A0A8I5ZT12 1.000 A0A8I5ZT12 →
A2RV61 0.998 A2RV61 →
Q07E15 0.994 Q07E15 →
Q6DN90 0.993 Q6DN90 →
Q9D3S3 0.993 Q9D3S3 →
Q09YI1 0.993 Q09YI1 →
Q60610 0.993 Q60610 →
Q3UMB5 0.993 Q3UMB5 →
PIK3C2B Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta 0.993 landscape →
Q6GYP7 0.993 Q6GYP7 →
O88480 0.992 O88480 →
Q07DV1 0.992 Q07DV1 →
B1A193 0.992 B1A193 →
Q6GYQ0 0.992 Q6GYQ0 →
Q86YS3 0.992 Q86YS3 →
Q9D684 0.992 Q9D684 →
Q2VUH7 0.992 Q2VUH7 →
O42400 0.992 O42400 →
Q8C115 0.991 Q8C115 →
Q3UHQ6 0.991 Q3UHQ6 →
Q07DW4 0.991 Q07DW4 →
O08774 0.991 O08774 →
B9EJA2 0.991 B9EJA2 →
O75815 0.991 O75815 →
P35611 0.990 P35611 →
Q2IBD4 0.990 Q2IBD4 →
Q9JIL5 0.990 Q9JIL5 →
Q2IBF7 0.990 Q2IBF7 →