GPKOW

G-patch domain and KOW motifs-containing protein · Q92917 · GPKOW on Sugi Atlas →

0 patent compounds predicted against GPKOW, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to GPKOW by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
The G Protein-Coupled Receptor Kinase Type 2 Inhibitor Paroxetine as Adjunctive Therapy to Improve Insulin Sensitivity in Patients With Type 2 Diabetes Mellitus PHASE3UNKNOWN
Pembrolizumab Plus Enfortumab Vedotin in Collecting Duct and Renal Medullary Carcinoma PHASE2RECRUITING
Pembrolizumab (MK-3475) in MM Patients With Residual Disease PHASE2COMPLETED
Melpida: Recombinant Adeno-associated Virus (serotype 9) Encoding a Codon Optimized Human AP4M1 Transgene (hAP4M1opt) PHASE1/PHASE2RECRUITING
Theophylline Treatment for Pseudohypoparathyroidism - Children 2-12 Years Old PHASE2ACTIVE_NOT_RECRUITING
Aerosol Combination Therapy of All-trans Retinoic Acid and Isotretinoin as A Novel Treatment for Inducing Neutralizing Antibodies in COVID -19 Infected Patients Better Than Vaccine : An Innovative Treatment PHASE2UNKNOWN
Safety and Efficacy of AAV9/AP4B1 (BFB-101) For Patients With AP4B1-related Hereditary Spastic Paraplegia Type 47 (SPG47) PHASE1/PHASE2NOT_YET_RECRUITING
First in Human Dose Escalation Study of Vactosertib (TEW-7197) in Subjects With Advanced Stage Solid Tumors PHASE1COMPLETED
Safety and Efficacy of the Fully Humanized Anti - VEGF Monoclonal Antibody LYN00101 PHASE1WITHDRAWN
Nebulised BromAc in Healthy Volunteers PHASE1COMPLETED
A First-in-Human Study of JAB-8263 in Adult Patients With Advanced Solid Tumors PHASE1COMPLETED
Targeting a Genetic Mutation in Glycine Metabolism With D-cycloserine EARLY_PHASE1COMPLETED
Thrombin Regulated Platelet Activation nanCOMPLETED
Avapritinib in the Treatment of Unresectable or Recurrent Metastatic GIST Non-exon18 Mutations of PDGFRA nanRECRUITING
Autophagy in Systemic Lupus Erythematosus nanUNKNOWN
Clinical Study of 68Ga-DOTA-BLP PET Imaging in Noninvasive Diagnosis of Malignant Tumors nanNOT_YET_RECRUITING
The Impact of Pharmacological and Electric Modulation of NMDA Pathway on the Cognitive Flexibility and Volitional Movement Preparation in Patients With Parkinson's Disease nanCOMPLETED
Changes in Skin Innervation of Neurologically Asymptomatic Type 2 Diabetic Patients: the Correlation With the Diabetic Parameters and Neurotrophins. nanUNKNOWN
FAP PET/CT or PET/MR Production in the Diagnosis, Staging, and Efficacy Assessment of Malignant Tumors Application nanCOMPLETED
Glycine and Magnesium+Thiamine for the Treatment of Primary Ciliary Dyskinesia nanRECRUITING
Lymphoid Tyrosine Phosphatase Gene Polymorphisms in Inflammatory Bowel Disease nanUNKNOWN
Evaluation of Serum Gasdermin D Level As a Potential Biomarker of Disease Activity in Vitiligo Patients nanUNKNOWN
Genotype-phenotype Correlation in Junctional Epidermolysis Bullosa nanUNKNOWN
Study of the Pathophysiological Mechanisms Involved in Bleeding Events nanCOMPLETED
The Effect Of DAAs on miRNA-122 And Insulin Resistance In Chronic HCV Patients nanUNKNOWN
Intravenous Terbutaline in Severe Status Asthmaticus nanUNKNOWN
The Role of MMPs in the CXCL12-Induced Invasion of Laryngeal and Hypopharyngeal Squamous Cell Carcinoma nanUNKNOWN
Aswan Heart Centre - Egyptian Healthy Volunteers nanRECRUITING
Mechanism and Immune Function Analysis of SARS-CoV-2 Infection in Hematologic Tumors nanACTIVE_NOT_RECRUITING
The Role of SDF-1/CXCR4 in Metastasis of Oral Squamous Cell Carcinoma nanUNKNOWN

Related proteins — ESM-2 sequence neighbours (a GPKOW binder may also engage these)

ProteinNameSimilarity
Q56A08 1.000 Q56A08 →
Q6NU07 0.988 Q6NU07 →
Q5U4Z3 0.987 Q5U4Z3 →
C0HAV3 0.986 C0HAV3 →
Q90X38 0.986 Q90X38 →
Q96I76 0.983 Q96I76 →
Q8VDP4 0.981 Q8VDP4 →
Q9WVR4 0.981 Q9WVR4 →
Q5T124 0.981 Q5T124 →
Q61858 0.980 Q61858 →
Q28H71 0.980 Q28H71 →
Q5U2X2 0.980 Q5U2X2 →
Q9H211 0.979 Q9H211 →
Q80ZX8 0.979 Q80ZX8 →
Q9D2E2 0.979 Q9D2E2 →
Q9CWK3 0.979 Q9CWK3 →
Q66HA5 0.979 Q66HA5 →
Q8R4E9 0.979 Q8R4E9 →
Q8R512 0.979 Q8R512 →
Q9D572 0.979 Q9D572 →
Q3T1I9 0.979 Q3T1I9 →
Q9Y103 0.978 Q9Y103 →
Q6MG81 0.978 Q6MG81 →
Q8IZP6 0.978 Q8IZP6 →
P97874 0.978 P97874 →
Q5PPF5 0.978 Q5PPF5 →
Q5R5V9 0.978 Q5R5V9 →
Q96P48 0.978 Q96P48 →
Q0IHN5 0.977 Q0IHN5 →
Q96I34 0.977 Q96I34 →