GTF2I

General transcription factor II-I · P78347 · GTF2I on Sugi Atlas →

0 patent compounds predicted against GTF2I, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to GTF2I by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Motor Function Efficacy of Pharmacological Treatments Targeting Energy Metabolism, in Parkinson's Patients PHASE4UNKNOWN
A Study of Bezafibrate in Mitochondrial Myopathy PHASE2COMPLETED
Testing the Combination of MLN4924 (Pevonedistat), Carboplatin, and Paclitaxel in Patients With Advanced Non-small Cell Lung Cancer (NSCLC) Who Have Previously Been Treated With Immunotherapy PHASE2ACTIVE_NOT_RECRUITING
PhII 5-Azacytidine Plus Valproic Acid and Eventually Atra in Intermediate II and High Risk MDS PHASE2COMPLETED
Value of Using Pioglitazone in Chronic Myeloid Leukemia Treatment PHASE2COMPLETED
Phase I Dose Finding and Proof-of-concept Study of Panobinostat With Standard Dose Cytarabine and Daunorubicin for Untreated Acute Myeloid Leukemia or Advanced Myelodysplastic Syndrome PHASE1COMPLETED
Endolymphatic Sac Tumors in a Population of Patients With Von Hippel-Lindau Disease:The Natural History and Pathobiology, and a Prospective Non-Randomized Clinical Trial of Hearing Preservation Surgery in Patients With Early Stage Endolymphatic Sac Tumors nanCOMPLETED
Autophagy in Systemic Lupus Erythematosus nanUNKNOWN
Family Resilience Initiative Research Program nanUNKNOWN
Steroid Treatment of Idiopathic Nephrotic Syndrome nanCOMPLETED
Gene Expression Variation and Implant Wound Healing Among Smokers and Diabetics nanCOMPLETED
A Study of the Genetic Analysis of Brain Disorders nanCOMPLETED
Role of Dairy Products in Weight Maintenance nanCOMPLETED
Predisposition Genes in Monogenic Diabetes (DIAMONO) nanCOMPLETED
Adrenocorticotropic Hormone (ACTH) Stimulation and G Protein nanCOMPLETED
Speech and Short-term Memory Functions in Dyslexia: a Combined MEG and EEG Study nanUNKNOWN
Evaluation of the Predictive Effect of Inflammatory Markers in MI Patients nanUNKNOWN
DNA Methylation and Autoimmune Thyroid Diseases nanCOMPLETED
Effect of Adenovirus E1A Oncogene on DNA Replication Dynamics nanUNKNOWN
Nuclear Myosin VI - a Therapeutic Target in Breast Cancer nanUNKNOWN
Recombinant Interferon Alfa-2b in Treating Patients With Melanoma nanCOMPLETED
Diagnosis of RSTS: Identification of the Acetylation Profiles as Epigenetic Markers for Assessing Causality of CREBBP and EP300 Variants. nanUNKNOWN
Observational Study to Assess Glycosylated Hemoglobin Changes After 6 Months of Treatment With Pioglitazone. nanCOMPLETED
Inter-regional Project of the Great Western Exploration Approach for Exome Molecular Causes Severe Intellectual Disability Isolated or Syndromic nanCOMPLETED
Zinc and the Synthesis of Zinc Binding Proteins (Protocol B) nanCOMPLETED
PHF19 Gene Expression and EZH2 Gene Deletion in Acute Myeloid Leukemia nanUNKNOWN
Spironolactone and XPB-1 Integrity in the TFIIH Complex nanENROLLING_BY_INVITATION
Nasturtium (Tropaeolum Majus L) Intake and Biochemical Parameters in Pre-diabetic Subjects in Bogota Colombia nanCOMPLETED
EPIgenetics and in Vivo Resistance of Chronic Myeloid Leukemia Stem Cells to Tyrosine Kinase Inhibitors nanUNKNOWN
Studying Tissue Samples From Patients With Stage II Colon Cancer Treated on Clinical Trial CLB-9581 nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a GTF2I binder may also engage these)

ProteinNameSimilarity
Q5U2Y1 1.000 Q5U2Y1 →
Q9ESZ8 1.000 Q9ESZ8 →
A7MB80 0.998 A7MB80 →
Q9JI57 0.996 Q9JI57 →
Q09449 0.996 Q09449 →
G5EC37 0.996 G5EC37 →
Q8IRH5 0.993 Q8IRH5 →
DNMT1 DNA (cytosine-5)-methyltransferase 1 0.993 landscape →
Q8CFC2 0.993 Q8CFC2 →
B7ZQJ9 0.993 B7ZQJ9 →
MYT1 Myelin transcription factor 1 0.993 landscape →
Q5HZJ0 0.993 Q5HZJ0 →
BPTF Nucleosome-remodeling factor subunit BPTF 0.993 landscape →
Q99PI5 0.993 Q99PI5 →
E1JH25 0.992 E1JH25 →
Q08639 0.992 Q08639 →
Q9UHL9 0.992 Q9UHL9 →
Q8W4A5 0.992 Q8W4A5 →
Q8C0P7 0.991 Q8C0P7 →
Q86TC9 0.991 Q86TC9 →
Q581T1 0.991 Q581T1 →
A0A0R4IBK5 0.991 A0A0R4IBK5 →
Q9NRR4 0.991 Q9NRR4 →
P22199 0.991 P22199 →
Q28Z18 0.991 Q28Z18 →
Q9FV71 0.991 Q9FV71 →
Q9XTT4 0.991 Q9XTT4 →
B4GT53 0.991 B4GT53 →
O14490 0.990 O14490 →
G5EGA3 0.990 G5EGA3 →