Sugi Predict

Sugi Predict / Targets / HACD3

HACD3

Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 · Q9P035 · HACD3 on Sugi Atlas →

0 patent compounds predicted against HACD3, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to HACD3 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Effects of Omega-3 Fatty Acids on the Human Gene Expression PHASE4COMPLETED
Study To Evaluate Beta Cell Function and Glycemic Outcome by Intensive Insulin Therapy PHASE4COMPLETED
Dinutuximab, Sargramostim, and Combination Chemotherapy in Treating Patients With Newly Diagnosed High-Risk Neuroblastoma PHASE2COMPLETED
Choline Effects - Pre-symptomatic AD PHASE1COMPLETED
Effect of Gemfibrozil on Serum Glycosylphosphatidylinositol (GPI) Phospholipase D and Triglycerides PHASE1COMPLETED
Fatty Acid Oxidation Defects and Insulin Sensitivity nanCOMPLETED
High Dose Omega-3 Fatty Acids in the Treatment of Sport Related Concussions nanCOMPLETED
The Roles of SAH Gene Family in Athrogenic Dyslipidemia in Postmenopausal Women nanUNKNOWN
Screening of Healthy Adults for Genetic Variations That Control Fatty Acid Processing nanCOMPLETED
Lipoprotein Lipase Expression in Chronic Lymphocytic Leukemia nanCOMPLETED
Clinical Application of PET Imaging Targeting GPA33 in Malignant Tumors nanNOT_YET_RECRUITING
for Adipose Tissue DIabetes VAriants (fATDIVA) nanCOMPLETED
Sleep Restriction and Postprandial Lipemia nanCOMPLETED
Immune Cell Response to Stimuli nanRECRUITING
Fatty Acid Metabolism and Insulin Sensitivity: the Role of Endurance Exercise nanCOMPLETED
Gene Expression, Metabolomic, Microbiome, and Calcium Metabolism in Response to Varied Vitamin D Dosages nanCOMPLETED
Exercise Intolerance Study in Long Chain Fatty Acid Oxidation Disorders nanRECRUITING
Combining Gene Variants to Improve Risk Prediction for Metabolic (Dysfunction)- Associated Fatty Liver Disease and Its Progression to Cirrhosis in Indian Individuals With Type 2 Diabetes nanCOMPLETED
Genetic Studies of Inflammatory Bowel Disease nanCOMPLETED
A Study of Genetic Influence on LDL Hyper-responsiveness in Patients Following a Ketogenic Diet nanRECRUITING
the Role of plin5 in the Development of Nonalcoholic Fatty Liver Disease. nanUNKNOWN
Identification of Genes Predisposing to Atherosclerosis nanCOMPLETED
Defining the Human Insulin Resistance Molecular Network; SIGNATURE nanNOT_YET_RECRUITING
Genomic Dissection of a QTL Affecting the Lipid Profile nanWITHDRAWN
Molecular & Clinical Evaluation of Low HDL Syndromes nanCOMPLETED
Personalized Nutrition in Young Adults: The Ability of Genetic Information to Motivate Changes in Omega-3 Consumption nanCOMPLETED
Improving Maternal and Child Health Through Prenatal Fatty Acid Supplementation nanACTIVE_NOT_RECRUITING
Dietary Intake of Whole Walnuts in Adult Subjects Under Low Cardiovascular Risk nanCOMPLETED
HYPOCHOL : A Genetically-based Strategy to Identify New Targets in Cholesterol Metabolism nanACTIVE_NOT_RECRUITING
Dietary Lipid Induced Insulin Resistance nanUNKNOWN

Related proteins — ESM-2 sequence neighbours (a HACD3 binder may also engage these)

ProteinNameSimilarity
Q8K2C9 — 1.000 Q8K2C9 →
A7YY55 — 1.000 A7YY55 →
Q5NVQ2 — 1.000 Q5NVQ2 →
Q7SY06 — 0.993 Q7SY06 →
Q5ZM57 — 0.988 Q5ZM57 →
Q0P5C7 — 0.972 Q0P5C7 →
A2AKM2 — 0.970 A2AKM2 →
Q60457 — 0.969 Q60457 →
Q6GNB5 — 0.969 Q6GNB5 →
O77761 — 0.965 O77761 →
Q5VWC8 — 0.965 Q5VWC8 →
O77760 — 0.965 O77760 →
Q9LJK3 — 0.965 Q9LJK3 →
SOAT1 Sterol O-acyltransferase 1 0.964 landscape →
Q8BH79 — 0.964 Q8BH79 →
Q61263 — 0.964 Q61263 →
Q4R8A8 — 0.964 Q4R8A8 →
Q32NI8 — 0.963 Q32NI8 →
Q9D3B1 — 0.963 Q9D3B1 →
Q4V8U5 — 0.963 Q4V8U5 →
Q8N609 — 0.962 Q8N609 →
Q3MHW7 — 0.962 Q3MHW7 →
F1QF89 — 0.962 F1QF89 →
O70536 — 0.962 O70536 →
Q4R516 — 0.962 Q4R516 →
Q4V8K1 — 0.961 Q4V8K1 →
Q9M6A3 — 0.961 Q9M6A3 →
Q1A3B0 — 0.961 Q1A3B0 →
Q687X5 — 0.961 Q687X5 →
SLC33A1 Acetyl-coenzyme A transporter 1 0.961 landscape →