HADH

Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial · Q16836 · HADH on Sugi Atlas →

0 patent compounds predicted against HADH, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to HADH by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Overcoming Primary Resistance to Immunotherapy in Metastatic Melanoma PHASE2COMPLETED
Acetylcarnitine and Insulin Sensitivity PHASE2COMPLETED
The Effects of Coenzyme A Combined With Abiraterone on Patients With CRPC PHASE1/PHASE2UNKNOWN
Atorvastatin, L-Carnitine and Non-Alcoholic Steatohepatitis PHASE2UNKNOWN
A Study of Bezafibrate in Mitochondrial Myopathy PHASE2COMPLETED
Thyroid Hormone for Treatment of Nonalcoholic Steatohepatitis in Veterans PHASE2RECRUITING
Metabolic Cofactor Supplementation in Alzheimer's Disease (AD) and Parkinson's Disease (PD) Patients PHASE2COMPLETED
Efficacy and Safety of the Treatment of Pyruvate Dehydrogenase Deficiency Patients With Glycerol Phenylbutyrate (RAVICTI) PHASE2RECRUITING
Carnitine Consumption and Augmentation in Pulmonary Arterial Hypertension PHASE1COMPLETED
Fatty Acid Oxidation Defects and Insulin Sensitivity nanCOMPLETED
Genomic Profiling of Mitochondrial Disease - Imaging Analysis for Precise Mitochondrial Medicine nanCOMPLETED
Triheptanoin (UX007) to Treat Citrate Transporter Deficiency nanNO_LONGER_AVAILABLE
Tissue Sample Study for Mitochondrial Disorders nanENROLLING_BY_INVITATION
Systemic Biomarkers of Brain Injury From Hyperammonemia nanRECRUITING
Glycine and Magnesium+Thiamine for the Treatment of Primary Ciliary Dyskinesia nanRECRUITING
North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC) nanRECRUITING
Prognostic Value of (DHODH) Expression in (HGSOC): A Comparative Study Between Neoadjuvant and Adjuvant Chemotherapy Settings nanNOT_YET_RECRUITING
Nicotinamide Riboside and Mitochondrial Biogenesis nanCOMPLETED
Nephroprotective Effects of Carnitine and (PDE5) Inhibitor Agent Against Contrast Media-induced Nephropathy (CMN) nanUNKNOWN
Lifestyle Intervention in Preparation for Pregnancy (LIPP) nanCOMPLETED
Mitoquines in COPD nanUNKNOWN
GDF-15 as a Biomarker for Mitochondrial Disease nanCOMPLETED
Longitudinal Study of Mitochondrial Hepatopathies nanSUSPENDED
McArdle Disease Treatment by Ketogenic Diet nanCOMPLETED
Effects of Parenteral L-carnitine Supplementation in Premature Neonates nanCOMPLETED
Effect of Acute Fructose Load in Human nanCOMPLETED
Study of Protein Translocation in Patients With Beta-Oxidation Disorders nanCOMPLETED
Mitochondrial Dysfunction in Diabetes nanCOMPLETED
Effect of Short-Term Exercise Training on ATP Synthesis in Relatives of Type 2 Diabetic Humans nanCOMPLETED
Mitochondria Inborn Errors of Metabolism and ANT Defects in Mitochondria Diseases nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a HADH binder may also engage these)

ProteinNameSimilarity
P00348 1.000 P00348 →
Q9WVK7 1.000 Q9WVK7 →
Q61425 1.000 Q61425 →
P34439 0.991 P34439 →
P41938 0.988 P41938 →
A1RI92 0.986 A1RI92 →
P45364 0.985 P45364 →
A3D684 0.985 A3D684 →
A5W6H0 0.985 A5W6H0 →
Q7MZ92 0.985 Q7MZ92 →
B1J5A5 0.984 B1J5A5 →
B0TL21 0.984 B0TL21 →
Q5QXH7 0.984 Q5QXH7 →
Q93Q12 0.984 Q93Q12 →
O49809 0.984 O49809 →
Q48GW3 0.984 Q48GW3 →
Q0HPB7 0.983 Q0HPB7 →
Q7MIS5 0.983 Q7MIS5 →
A7MS61 0.983 A7MS61 →
Q4ZRA0 0.983 Q4ZRA0 →
A4Y897 0.983 A4Y897 →
Q1Q8J9 0.982 Q1Q8J9 →
Q8DB47 0.982 Q8DB47 →
Q9F0Y7 0.982 Q9F0Y7 →
Q0HWN3 0.982 Q0HWN3 →
Q83PG1 0.982 Q83PG1 →
Q1I7D4 0.982 Q1I7D4 →
A4XSM8 0.982 A4XSM8 →
B2TVJ5 0.982 B2TVJ5 →
Q1R466 0.982 Q1R466 →