Sugi Predict

Sugi Predict / Targets / HBZ

HBZ

Hemoglobin subunit zeta · P02008 · HBZ on Sugi Atlas →

0 patent compounds predicted against HBZ, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to HBZ by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
The Potential Hepatoprotective Effect of Metformin in Patients With Beta Thalassemia Major PHASE4UNKNOWN
Deciphering Effects of Thalidomide on Red Blood Cells in Transfusion Dependents Beta Thalassemia Patients PHASE3COMPLETED
A Study Evaluating Gene Therapy With BB305 Lentiviral Vector in Sickle Cell Disease PHASE3ACTIVE_NOT_RECRUITING
The Efficacy of Jobelyn (Sorghum Bicolor Extract)in the Treatment of Sickle Cell Anemia PHASE1/PHASE2COMPLETED
5-Azacytidine and Phenylbutyrate to Treat Severe Thalassemia PHASE2COMPLETED
Trial of HQK-1001 in Beta Thalassemia Intermedia in Lebanon PHASE2COMPLETED
Stem Cell Transplant in Sickle Cell Disease and Thalassemia PHASE2ACTIVE_NOT_RECRUITING
A Phase I/II Trial of Recombinant-Methionyl Human Stem Cell Factor (SCF) in Adult Patients With Sickling Disorders PHASE1COMPLETED
A Phase 1 Study of Gene-modified Autologous Hematopoietic Stem Cell (BD211) Treating β-thalassemia Major PHASE1RECRUITING
Hydroxyurea and Erythropoietin to Treat Sickle Cell Anemia PHASE1COMPLETED
Pumilio1 (PUM1) Expression, Sickle Cell Anemia, β-thalassemia Intermedia nanNOT_YET_RECRUITING
Association of Hb F Level With Clinical Severity of Beta Thalassemia nanUNKNOWN
Thalassemia (Cooley's Anemia) Clinical Research Network (TCRN) nanCOMPLETED
Effect of Aquatic Exercises on Muscle Strength and Quality of Life in Children With Sickle Cell Anemia nanCOMPLETED
The Prevelence of HBB c.93-21 G-A in β Thalassemia Patients nanUNKNOWN
Predisposing Factors for Liver Diseases in Patients With Chronic Hemolytic Anemia nanNOT_YET_RECRUITING
Safety and Efficacy Evaluation of Autologous CRISPR-Cas12b Edited Hematopoietic Stem Cells nanRECRUITING
'MyPinkMom' Educational Intervention for Pregnant Women With Anaemia nanUNKNOWN
Screening for Alpha Thalassemia in Healthy Volunteers nanACTIVE_NOT_RECRUITING
Genetic Variants Affecting the Clinical Severity of Beta Thalassemia nanUNKNOWN
Detection Of β-thalassemia Carriers In Assiut nanUNKNOWN
Pharmacotherapy Prescribing Pattern and the Adherence Level to Iron Chelation Therapy in Thalassemia nanCOMPLETED
STUDY INCIDENCE AND CHARACTERISTICS OF MALIGNANT NEOPLASIES IN PATIENTS WITH HEMOGLOBINOPATHY FOLLOWED IN ITALY nanRECRUITING
EKLF Gene Expression in β-thalassemia nanNOT_YET_RECRUITING
Sexual Maturation in β-Thalassemia Major Patients in Assiut University Hospital nanUNKNOWN
Cohort Study of Sickle Cell Patients Evaluating Analgesic Strategies and Their Consequences nanCOMPLETED
Sickle Cell Trait in Football Players nanUNKNOWN
Heart Arteries and Sickle Cell Disease / Coeur Artères DREpanocytose nanUNKNOWN
Study of the Role of Genetic Modifiers in Hemoglobinopathies nanRECRUITING
Lipid Balance in Adult Sickle Cell Patients nanACTIVE_NOT_RECRUITING

Related proteins — ESM-2 sequence neighbours (a HBZ binder may also engage these)

ProteinNameSimilarity
P13786 — 1.000 P13786 →
P06347 — 1.000 P06347 →
P63107 — 0.996 P63107 →
P63106 — 0.995 P63106 →
P69905 — 0.995 P69905 →
P69907 — 0.995 P69907 →
P10892 — 0.994 P10892 →
P09839 — 0.993 P09839 →
P01956 — 0.993 P01956 →
Q9TSN9 — 0.993 Q9TSN9 →
P02009 — 0.992 P02009 →
P19002 — 0.992 P19002 →
Q9TSN7 — 0.992 Q9TSN7 →
P09908 — 0.992 P09908 →
P01967 — 0.992 P01967 →
P01923 — 0.991 P01923 →
P01973 — 0.991 P01973 →
P28780 — 0.991 P28780 →
P07421 — 0.991 P07421 →
P01960 — 0.991 P01960 →
Q7JFN6 — 0.991 Q7JFN6 →
P07405 — 0.991 P07405 →
P18977 — 0.991 P18977 →
P01958 — 0.991 P01958 →
P23601 — 0.990 P23601 →
P14389 — 0.990 P14389 →
P10885 — 0.990 P10885 →
P02018 — 0.990 P02018 →
P02007 — 0.990 P02007 →
P07425 — 0.990 P07425 →