HIGD1A

HIG1 domain family member 1A, mitochondrial · Q9Y241 · HIGD1A on Sugi Atlas →

0 patent compounds predicted against HIGD1A, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to HIGD1A by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
A Study of the Efficacy and Safety of MT1621 in Thymidine Kinase 2 (TK2) Deficiency (Treatment naïve) PHASE3WITHDRAWN
CoQ10 and Exercise for Mitochondrial Dysfunction in Advance Kidney Disease PHASE3RECRUITING
ONC201 in Recurrent/Refractory Metastatic Breast Cancer and Advanced Endometrial Carcinoma PHASE2COMPLETED
Dynamics of Muscle Mitochondria in Type 2 Diabetes (DYNAMMO T2D) EARLY_PHASE1COMPLETED
Role of Autophagy in Type 2 Diabetes Microvascular Dysfunction EARLY_PHASE1RECRUITING
ACTIV- Exercise Intervention in Healthy Young Men nanCOMPLETED
The Natural History of Mitochondrial Diseases nanRECRUITING
Role of Sorcin and Annexin A3 in Breast Cancer Patients nanUNKNOWN
Mitochondrial Dysfunction in Phelan-McDermid Syndrome nanCOMPLETED
Diabetic Cardiomyopathy and Heart Failure nanWITHDRAWN
Universal Rare Gene Study: A Registry and Natural History Study of Retinal Dystrophies Associated With Rare Disease-Causing Genetic Variants nanRECRUITING
Tissue Sample Study for Mitochondrial Disorders nanENROLLING_BY_INVITATION
Exercise Training Effects on Muscle Function in Adults With Mitochondrial Myopathy nanRECRUITING
Mitigating Mitochondrial RNA Release During Aging to Control Inflammation and Senescence nanNOT_YET_RECRUITING
Dynamics of Muscle Mitochondria in Type 2 Diabetes Exercise nanCOMPLETED
Clinical Value of Plasma Humanin in Acute Kidney Injury nanUNKNOWN
Relationship Between Mitochondrial Dysfunction and Fatique in Cancer Patients Following External Beam Radiation Therapy nanCOMPLETED
Measuring Protein Turnover in Humans Across the Lifespan by Metabolic Labeling With Deuterium Oxide nanRECRUITING
Abnormalities in the Effects of Insulin and Exercise on Glucose- and Lipid Metabolism in Obesity and Type 2 Diabetes nanCOMPLETED
North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC) nanRECRUITING
Identification of New Candidate Genes in Patients With Mitochondrial Disease by High Resolution Chromosome Analysis on DNA Chip nanCOMPLETED
Skeletal Muscle Regeneration in Survivors of Critical Illness: How to Prevent Satellite Cell Failure? nanRECRUITING
Clinical Study of Hydroxytyrosol (HT) in Mitochondrial Diseases nanCOMPLETED
Mitochondrial Disease-associated ImmunoDeficiencies nanRECRUITING
A Study Into the Underlying Biochemical Pathways Involved in Parkinson's Disease, Such as Mitochondrial (Cellular Powerhouse) Dysfunction nanCOMPLETED
Exome Analysis in Hearing Impaired Patients nanUNKNOWN
Mitochondrial Dysfunction in Diabetes nanCOMPLETED
Nicotinamide Riboside and Mitochondrial Biogenesis nanCOMPLETED
Exercise-mediated Rescue of Mitochondrial Dysfunctions Driving Insulin Resistance nanCOMPLETED
Insulin Deprivation on Brain Structure and Function in Humans With Type 1 Diabetes nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a HIGD1A binder may also engage these)

ProteinNameSimilarity
Q5NVQ1 1.000 Q5NVQ1 →
Q9JLR9 0.999 Q9JLR9 →
A8MV81 0.997 A8MV81 →
Q76I25 0.996 Q76I25 →
Q8VH49 0.993 Q8VH49 →
Q9P298 0.992 Q9P298 →
Q99JY6 0.989 Q99JY6 →
Q9BW72 0.981 Q9BW72 →
B6K2Z6 0.979 B6K2Z6 →
C4QV79 0.975 C4QV79 →
C1G794 0.974 C1G794 →
C5JIT3 0.974 C5JIT3 →
A6RBB3 0.973 A6RBB3 →
C5GDJ2 0.973 C5GDJ2 →
Q03713 0.972 Q03713 →
A6ZM32 0.972 A6ZM32 →
C7GT60 0.972 C7GT60 →
A5E2M7 0.972 A5E2M7 →
Q6CBQ8 0.972 Q6CBQ8 →
D4DDK2 0.972 D4DDK2 →
P53721 0.972 P53721 →
P53311 0.971 P53311 →
C6H220 0.971 C6H220 →
Q9UTB1 0.971 Q9UTB1 →
Q9CQJ1 0.971 Q9CQJ1 →
C5DWC4 0.970 C5DWC4 →
C0NUL6 0.970 C0NUL6 →
C0RYW2 0.970 C0RYW2 →
Q756G1 0.970 Q756G1 →
A1CXG2 0.970 A1CXG2 →