HSD17B12

Very-long-chain 3-oxoacyl-CoA reductase · Q53GQ0 · HSD17B12 on Sugi Atlas →

0 patent compounds predicted against HSD17B12, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to HSD17B12 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
The Role of CYP8B1 Polymorphisms in Modulating the Biochemical Pathways Affected by SGLT2 Inhibitors in T2DM and Obesity PHASE4COMPLETED
Theca Cell Function in Adolescents With Polycystic Ovary Syndrome (PCOS) PHASE3COMPLETED
Comparison of Coenzyme A and Pantethine Capsule for Safety and Efficacy On Patients With Hyperlipidemia PHASE3COMPLETED
Atorvastatin, L-Carnitine and Non-Alcoholic Steatohepatitis PHASE2UNKNOWN
Smith-Lemli-Opitz Syndrome and Cholic Acid PHASE1/PHASE2COMPLETED
Toxicity and Efficacy Evaluation of Topical Minoxidil in Acne Vulgaris PHASE1/PHASE2UNKNOWN
The Effects of Coenzyme A on Serum Lipids in Patients With Hyperlipidemia PHASE2COMPLETED
AMG 386 and Abiraterone for Advanced Prostate Cancer PHASE2COMPLETED
Androgen Reduction in Congenital Adrenal Hyperplasia PHASE2WITHDRAWN
Cholic Acid for Hepatic Steatosis in Lipodystrophy PHASE2COMPLETED
Knockdown of HSD17B13 mRNA, Pharmacokinetics, Safety, and Tolerability, of AZD7503 in Non-Alcoholic Fatty Liver Disease PHASE1COMPLETED
Biomarkers in Bone Marrow and Blood Samples From Patients With Prostate Cancer Treated With Ketoconazole nanWITHDRAWN
Mutation Analysis of 17α-Hydroxylase nanUNKNOWN
Mutation Analysis of 17βhydroxysteroid Dehydrogenase 3 Deficiency nanUNKNOWN
Linear Growth of Children With Congenital Adrenal Hyperplasia nanUNKNOWN
Polycystic Ovary Syndrome in Type 1 Diabetes nanNOT_YET_RECRUITING
Androgens and NAFLD Longitudinal Cohort Study nanRECRUITING
Study of Smith-Lemli-Opitz Syndrome nanCOMPLETED
A Prospective Observational Study of Biomarkers for a Personalised IVF Treatment nanUNKNOWN
Ovarian Morphology and Theca Cell Androgen Production in Women With Polycystic Ovary Syndrome (PCOS) nanCOMPLETED
Effect of Surgical or Conservative Approach in Patients With Adrenal Incidentalomas nanUNKNOWN
Final Height in Patients With CAH nanUNKNOWN
11C-Acetate PET/CT Non-FDG-Avid Tumors nanUNKNOWN
Pattern of Gene Expression in Adipose Tissue From Patients With Cushing Syndrome nanCOMPLETED
Gene Polymorphisms Influencing Steroid Synthesis and Action nanWITHDRAWN
Screening of Healthy Adults for Genetic Variations That Control Fatty Acid Processing nanCOMPLETED
Impact Of Choline in Patients With NAFLD nanUNKNOWN
Impact of 11-oxygenated Androgens on Metabolic Dysfunction of Women With Polycystic Ovary Syndrome nanUNKNOWN
Exercise Capacity, Physical Fitness, and Physical Activity Levels in Children With CAH nanCOMPLETED
Omics-based Predictors of NAFLD/Potential NASH nanUNKNOWN

Related proteins — ESM-2 sequence neighbours (a HSD17B12 binder may also engage these)

ProteinNameSimilarity
Q6QA33 1.000 Q6QA33 →
O70503 1.000 O70503 →
Q6P7R8 1.000 Q6P7R8 →
Q4R5G7 1.000 Q4R5G7 →
Q5E9H7 1.000 Q5E9H7 →
Q8AVY8 0.998 Q8AVY8 →
Q6P3L6 0.997 Q6P3L6 →
O17795 0.997 O17795 →
Q5XG41 0.997 Q5XG41 →
Q28IU1 0.996 Q28IU1 →
O57314 0.995 O57314 →
A5PJF6 0.994 A5PJF6 →
Q17703 0.994 Q17703 →
Q09517 0.994 Q09517 →
Q5ZJG8 0.994 Q5ZJG8 →
Q17704 0.994 Q17704 →
O54939 0.993 O54939 →
Q3SXM5 0.993 Q3SXM5 →
Q5R7K0 0.992 Q5R7K0 →
Q60V51 0.992 Q60V51 →
P70385 0.992 P70385 →
A8N6B4 0.991 A8N6B4 →
Q8N3Y7 0.991 Q8N3Y7 →
HSD17B3 17-beta-hydroxysteroid dehydrogenase type 3 0.991 landscape →
A8Q1U2 0.991 A8Q1U2 →
Q10245 0.990 Q10245 →
Q6QA32 0.990 Q6QA32 →
A6RBW9 0.989 A6RBW9 →
Q9FYL6 0.988 Q9FYL6 →
Q05A13 0.988 Q05A13 →