Sugi Predict
/ Targets
/ HVCN1
Top predicted compounds (top 20 by supporting neighbours, then confidence)
| Compound | Confidence | Supporting neighbours |
|---|
Clinical trials — most relevant to HVCN1 by text similarity (a relevance ranking, not an exhaustive list)
| Trial | Phase | Status |
|---|
| A Double-blind Study Evaluating the Efficacy, Safety, and Tolerability of Zorevunersen in Patients With Dravet Syndrome |
PHASE3 | RECRUITING |
| An Open-Label Study to Investigate the Safety of Single and Multiple Ascending Doses in Children and Adolescents With Dravet Syndrome |
PHASE1/PHASE2 | COMPLETED |
| A Phase I/II, First-In-Human Trial to Evaluate the Safety, Tolerability, and Pharmacokinetic Activity to Prevent or Treat Neuropsychiatric Symptoms in Pediatric Subjects With Timothy Syndrome |
PHASE1/PHASE2 | NOT_YET_RECRUITING |
| 4-Aminopyridine in Episodic Ataxia Type 2 |
PHASE2 | WITHDRAWN |
| Amiloride Hydrochlorothiazide as Treatment of Acute Inflammation of the Optic Nerve |
PHASE2 | UNKNOWN |
| StereoTactic Arrhythmia Radiotherapy in the NetherLands no. 2 |
PHASE2 | RECRUITING |
| Pathophysiology Based Therapy of Early Onset Epileptic Encephalopathies |
PHASE2 | WITHDRAWN |
| Efficacy and Safety of AUT00063 Versus Placebo in Age-Related Hearing Loss |
PHASE2 | COMPLETED |
| Pembrolizumab Plus Enfortumab Vedotin in Collecting Duct and Renal Medullary Carcinoma |
PHASE2 | RECRUITING |
| A Phase I, Open-Labeled, Single-Arm, Dose Escalation, Clinical and Pharmacology Study of Dichloroacetate (DCA) in Patients With Recurrent and/or Metastatic Solid Tumours |
PHASE1 | COMPLETED |
| Preoperative Imatinib and Fampridine in KIT Mutant Gastrointestinal Stromal Tumor |
PHASE1 | RECRUITING |
| Genetic Determinants of Sudden Cardiac Death |
nan | COMPLETED |
| Factors Affecting Salt Intake in Young Adults |
nan | UNKNOWN |
| The Involvement of ATP Sensitive Potassium Channel in Migraine Aura and Migraine Pain. |
nan | UNKNOWN |
| Evaluation of the Effects of KCNQ1 Mutation on Insulin Tolerance and Obsessive Compulsive Features in Long QT Romano-Ward Syndrome Patients. |
nan | UNKNOWN |
| MRI-phenotyping of Patients With Pathogenic Anoctamin 5 Variants |
nan | RECRUITING |
| The Physiological Effects of Human Ether-a-go-go-Related Gene (hERG)Blockade on Metabolism |
nan | COMPLETED |
| Classical Trigeminal Neuralgia and Sodium Channel Mutations |
nan | COMPLETED |
| Genetic Analysis of Heart Channelopathies in Brazilian Patients and Their Relatives |
nan | UNKNOWN |
| Malignant Hyperthermia in Czech Republic: Description of the Biggest Slavonic Group of Patients Investigated for Risk of Malignant Hyperthermia |
nan | COMPLETED |
| The Energetic Origin of Neurodegeneration in MS |
nan | COMPLETED |
| Sodium Channel Splicing in Heart Failure Trial |
nan | COMPLETED |
| Sodium Channel Splicing in Heart Failure Trial (SOCS-HEFT) Prospective Study |
nan | UNKNOWN |
| Gene-STEPS: Shortening Time of Evaluation in Paediatric Epilepsy Services |
nan | UNKNOWN |
| Studying Nerve Function and Structure in Charcot-Marie-Tooth Disease, Anti-MAG Neuropathy and CIDP |
nan | RECRUITING |
| Relationship Between Polymorphisms of TRPV1 and KCC2 Gene in Children With Febrile Seizures |
nan | COMPLETED |
| The Use of Antiarrhythmic Drugs in Pediatrics |
nan | UNKNOWN |
| Genes, Proteins, and Metabolites in Drug-resistant Epilepsy (DRE) Patients |
nan | NOT_YET_RECRUITING |
| Detection of Clinically Significant Prostate Cancer Using a Urinary Multimarker Sensor |
nan | UNKNOWN |
| Multidisciplinary Study of Right Ventricular Dysplasia |
nan | COMPLETED |
Related proteins — ESM-2 sequence neighbours (a HVCN1 binder may also engage these)