HYOU1

Hypoxia up-regulated protein 1 · Q9Y4L1 · HYOU1 on Sugi Atlas →

0 patent compounds predicted against HYOU1, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to HYOU1 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Hypoxia-inducible Factor Prolyl Hydroxylase Inhibitors on Sarcopenia in Hemodialysis Patients PHASE4NOT_YET_RECRUITING
R-CHOP-14 Versus R-CHOP-21 and Darbepoetin Alpha in Patients Aged 60-80 Years With Diffuse Large B-cell Lymphoma PHASE3COMPLETED
Effect of Deferoxamine on Wound Healing Rate in Patients With Diabetes Foot Ulcers PHASE2NOT_YET_RECRUITING
Desferal Administration to Improve the Impaired Reaction to Hypoxia in Diabetes PHASE2UNKNOWN
The Effect of Roxadustat on Renal Oxygenation in Diabetes Nephropathy PHASE2NOT_YET_RECRUITING
Nitroglycerin Plus Intracranial Radiotherapy for Brain Metastases in NSCLC Patients PHASE2COMPLETED
MBM-02 (Tempol) for the Treatment of Glioblastoma Multiforme (GBM) PHASE2UNKNOWN
Study of the Effects of Iron on Lung Blood Pressure at High Altitude PHASE2WITHDRAWN
Post-Cardiac Surgery Acute Kidney Injury Prevention by Administration of Proton Pump Inhibitor (P2 Trial) PHASE2RECRUITING
Paclitaxel-Carboplatin-Bevacizumab +/- Nitroglycerin in Metastatic Non-Squamous-Non-Small Cell Lung Cancer PHASE2COMPLETED
Multiple N-of-1 Trials of (Intermittent) Hypoxia Therapy in Parkinson's Disease PHASE1/PHASE2COMPLETED
First-line Irinotecan, Lederfolin and 5FU (FOLFIRI) and Bevacizumab in Patients With Advanced Colorectal Cancer PHASE2COMPLETED
SUTENT (SUNITINIB, SU11248)in Patients With Recurrent or Progressive Glioblastoma Multiforme PHASE2UNKNOWN
A Pilot Study of EZN-2968, an Antisense Oligonucleotide Inhibitor of HIF-1alpha, in Adults With Advanced Solid Tumors With Liver Metastases PHASE1COMPLETED
Study Effects of Intermittent Hypoxia on Restoring Hand Function Following SCI PHASE1COMPLETED
Remote Ischemic Postconditioning Increases HIF-1α Plasma Levels and Improves Cardiac Markers After Cardiac Surgery nanCOMPLETED
Mitochondrial Function of Immune Cells in Sepsis nanCOMPLETED
Selecting Hypoxic Tumours for Treatment Modification nanRECRUITING
Hypoxia Inducible Factor 1 Alpha as a Novel Biomarker in Septic Shock nanCOMPLETED
Study of the Effects of Iron Levels on the Lungs at High Altitude nanCOMPLETED
Inhibition of SENP1 for the Suppression of OS Growth and Metastasis nanUNKNOWN
Pituitary Derived-Intermedin is an Estrogen-Modulated Factor for Reducing Blood Pressure nanUNKNOWN
Hypoxia Inducible factor1-Alpha Genetic Polymorphism of Obstructive Sleep Apnea nanUNKNOWN
Postexercise Hot-Water Immersion on Exercise Performance in Hypoxia nanNOT_YET_RECRUITING
Effects of High Altitude on AMPK Activation nanRECRUITING
Oxygen Transport in Normobaric vs. Hypobaric Hypoxia nanCOMPLETED
Studies on the Adaptive Responses to Hypoxia nanCOMPLETED
High Altitude Medical Research Expedition Himlung 2013 - a Study of Human Adaption to Hypoxia nanCOMPLETED
S9304A Study of Protein Expression in Tumor Tissue Samples From Patients With Stage II or Stage III Rectal Cancer Enrolled in Clinical Trial SWOG-9304 nanCOMPLETED
Effect of Post Covid-19 Hypoxia on Placenta of Normal Pregnant Women: A Possible Role of Hypoxia Inducible Factor-1α. nanUNKNOWN

Related proteins — ESM-2 sequence neighbours (a HYOU1 binder may also engage these)

ProteinNameSimilarity
Q60432 1.000 Q60432 →
Q9JKR6 1.000 Q9JKR6 →
Q7ZUW2 1.000 Q7ZUW2 →
Q63617 1.000 Q63617 →
Q5ZLK7 0.994 Q5ZLK7 →
Q566I3 0.990 Q566I3 →
Q28056 0.989 Q28056 →
Q0VA61 0.987 Q0VA61 →
P52194 0.984 P52194 →
ABCF1 ATP-binding cassette sub-family F member 1 0.983 landscape →
O54861 0.983 O54861 →
Q8BSY0 0.982 Q8BSY0 →
Q0JLS6 0.982 Q0JLS6 →
ERP29 Endoplasmic reticulum resident protein 29 0.982 landscape →
Q7ZU90 0.982 Q7ZU90 →
P35564 0.981 P35564 →
AP3D1 AP-3 complex subunit delta-1 0.981 landscape →
Q5XHZ0 0.981 Q5XHZ0 →
Q16W06 0.981 Q16W06 →
A1XD97 0.981 A1XD97 →
A2WKK5 0.981 A2WKK5 →
B4KPU0 0.981 B4KPU0 →
Q767K6 0.981 Q767K6 →
Q27974 0.981 Q27974 →
MBTPS1 Membrane-bound transcription factor site-1 protease 0.981 landscape →
KDM1A Lysine-specific histone demethylase 1A 0.981 landscape →
Q08BC6 0.980 Q08BC6 →
P57759 0.980 P57759 →
Q09332 0.980 Q09332 →
Q295V5 0.980 Q295V5 →