HYPK

Huntingtin-interacting protein K · Q9NX55 · HYPK on Sugi Atlas →

0 patent compounds predicted against HYPK, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to HYPK by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
An Extension of SKY-0515 in Participants With Huntington's Disease PHASE2/PHASE3ENROLLING_BY_INVITATION
Study to Evaluate the Pharmacodynamics, Safety and Efficacy of SKY-0515 in Participants With Huntington's Disease PHASE2/PHASE3RECRUITING
Study of SKY-0515 for Safety, Efficacy, and Pharmacodynamics in Participants With Huntington's Disease PHASE2/PHASE3ACTIVE_NOT_RECRUITING
A Randomized Study of SPK-10001 Gene Therapy in Participants With Huntington's Disease PHASE1/PHASE2RECRUITING
Creatine Therapy for Huntington's Disease PHASE1/PHASE2COMPLETED
Safety and Tolerability Study of Phenylbutyrate in Huntington's Disease (PHEND-HD) PHASE2COMPLETED
Tianasen (ASO-GNAO1) for GNAO1-Encephalopathy With Epilepsy and Movement Disorders. PHASE1/PHASE2RECRUITING
A Clinical Study to Evaluate the Safety, Tolerability, and Efficacy of BBM-D101 in the Treatment of Duchenne Muscular Dystrophy. PHASE1/PHASE2RECRUITING
Study to Measure Cerebrospinal Fluid Mutant Huntingtin Protein in Participants With Early Manifest Stage I or Stage II Huntington's Disease PHASE1COMPLETED
Nilotinib in Huntington's Disease PHASE1UNKNOWN
Effects of Lithium Therapy on Blood-based Therapeutic Targets in Parkinson's Disease. PHASE1COMPLETED
Evaluation of the Safety and Efficacy of BBM-D101 to Treat Patients with Duchenne Muscular Dystrophy EARLY_PHASE1RECRUITING
Biology-Driven Cognitive Profiling in Huntington's Disease nanACTIVE_NOT_RECRUITING
Family Health After Predictive Huntington Disease (HD) Testing nanCOMPLETED
Evaluating the Relationship of Morphine Consumption and Pain-related Molecules in Hepatic Surgical Patients nanCOMPLETED
Efficacy of Cognitive Rehabilitation Using Virtual Reality and Computer-based Cognitive Stimulation on Cognitive Impairment Associated to Movement Disorders nanCOMPLETED
Huntington's Disease Young Adult Study 2.0 nanUNKNOWN
Development of Assessments for Later Stage HD nanUNKNOWN
Biomarker Research in Inherited Movement Disorders nanRECRUITING
CSF Protein Markers as Prognostic Indicators of the Response to CSF Shunt in Normotensive Hydrocephalus nanRECRUITING
Genetic Characterization of Parkinson's Disease nanCOMPLETED
Evaluation of Three Tests to Assess Social Cognition in Huntington Disease nanRECRUITING
Research of Biomarkers in Parkinson Disease nanCOMPLETED
Urinary Kallikrein and Hypertension: A Prospective Study nanCOMPLETED
The Epidemiology of Parkinson's Disease in Croatia and the Influence of Genetic Factors and Microbiota on the Progression and Treatment Outcomes of the Disease (GiOPARK) nanUNKNOWN
Investigating the Genetic and Phenotypic Presentation of Ataxia and Nucleotide Repeat Diseases nanACTIVE_NOT_RECRUITING
Study of Biomarkers That Predict the Evolution of Huntington's Disease nanUNKNOWN
Gut Microbiomes in HD nanRECRUITING
REGISTRY-JHD - an Observational Study of the European Huntington's Disease Network (EHDN) nanCOMPLETED
Registry and Natural History Study for Early Onset Hereditary Spastic Paraplegia nanRECRUITING

Related proteins — ESM-2 sequence neighbours (a HYPK binder may also engage these)

ProteinNameSimilarity
Q2PFU1 1.000 Q2PFU1 →
Q9CR41 1.000 Q9CR41 →
Q68F90 0.967 Q68F90 →
Q6PFL6 0.967 Q6PFL6 →
Q6QN10 0.966 Q6QN10 →
Q6IP73 0.965 Q6IP73 →
Q5E9A1 0.965 Q5E9A1 →
Q5ZIN1 0.964 Q5ZIN1 →
A6R641 0.964 A6R641 →
A1DLM0 0.963 A1DLM0 →
Q8JIU7 0.963 Q8JIU7 →
Q9H009 0.963 Q9H009 →
Q6ICZ8 0.962 Q6ICZ8 →
Q86S66 0.962 Q86S66 →
Q60817 0.962 Q60817 →
NACA Nascent polypeptide-associated complex subunit alpha 0.962 landscape →
Q5R9I9 0.962 Q5R9I9 →
Q9SZY1 0.962 Q9SZY1 →
Q96CT7 0.962 Q96CT7 →
A7EIZ1 0.962 A7EIZ1 →
Q2H4Z2 0.962 Q2H4Z2 →
Q8AWF2 0.961 Q8AWF2 →
Q5AYK0 0.961 Q5AYK0 →
Q28HN4 0.961 Q28HN4 →
Q1DHR3 0.961 Q1DHR3 →
A1CMF8 0.960 A1CMF8 →
Q94JX9 0.960 Q94JX9 →
Q61UX1 0.960 Q61UX1 →
Q8LCV1 0.960 Q8LCV1 →
Q5BJP2 0.960 Q5BJP2 →