IDH3B

Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial · O43837 · IDH3B on Sugi Atlas →

0 patent compounds predicted against IDH3B, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to IDH3B by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
A Study to Evaluate HMPL-306 in Patients With IDH1or IDH2-mutated Acute Myeloid Leukemia PHASE3RECRUITING
IDH1 (AG 120) Inhibitor in Patients With IDH1 Mutated Myelodysplastic Syndrome PHASE2ACTIVE_NOT_RECRUITING
Using the Anticancer Drug Olaparib to Treat Relapsed/Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome With an Isocitrate Dehydrogenase (IDH) Mutation PHASE2ACTIVE_NOT_RECRUITING
Treatment With Azacitidine of Recurrent Gliomas With IDH1/2 Mutation PHASE2UNKNOWN
Phase 2 Study of IDH305 in Low Grade Gliomas PHASE2WITHDRAWN
IDH2 (AG 221) Inhibitor in Patients With IDH2 Mutated Myelodysplastic Syndrome PHASE2ACTIVE_NOT_RECRUITING
A Clinical Trial of Olutasidenib in Patients With Acute Myeloid Leukemia PHASE2RECRUITING
Testing the Combination of Belinostat and SGI-110 (Guadecitabine) or ASTX727 for the Treatment of Unresectable and Metastatic Conventional Chondrosarcoma PHASE2ACTIVE_NOT_RECRUITING
Nivolumab in Patients With IDH-Mutant Gliomas With and Without Hypermutator Phenotype PHASE2ACTIVE_NOT_RECRUITING
MEN1703 (SEL24) in Participants With Acute Myeloid Leukemia PHASE1/PHASE2COMPLETED
Nivolumab for Recurrent or Progressive IDH Mutant Gliomas PHASE2COMPLETED
Study to Evaluate Imetelstat in Patients With High-Risk MDS or AML Failing HMA-based Therapy PHASE2ACTIVE_NOT_RECRUITING
Study Evaluating the Efficacy and Safety of the Addition of Ivosidenib to Oral Azacitidine (Onureg®) in Patients Over 55 With Acute Myeloid Leukemia (AML) and IDH1 Mutation, in Complete Remission After Intensive Chemotherapy. PHASE2NOT_YET_RECRUITING
Safety and Efficacy Study in Recurrent or Progressive Grade III or IV IDH1 Mutated Glioma PHASE1/PHASE2RECRUITING
Studying the Biology of IDH-mutant Gliomas Via Longitudinal Observation of 2-hydroxyglutarate (2-HG) Using MR Spectroscopy PHASE2SUSPENDED
Olutasidenib Single Plus Combo Therapy in IDH1mut AML After Induction and Consolidation PHASE1RECRUITING
IDH2 Inhibition Using Enasidenib as Maintenance Therapy for IDH2-mutant Myeloid Neoplasms Following Allogeneic Stem Cell Transplantation PHASE1COMPLETED
CCRT With Temozolomide Versus RT Alone in Patients With IDH Wild-type/TERT Promoter Mutation Grade II/III Gliomas EARLY_PHASE1UNKNOWN
Screening of IDH1 and IDH2 Gene Mutations in Adult Acute Myeloid Leukemia for Possible Targeted Therapy nanUNKNOWN
Construction and Application of an IDH Mutation-Targeted PET/MRI Imaging Framework for Precision Diagnosis of Gliomas nanRECRUITING
IDH1/IDH2 Mutation Frequency in Acute Myeloblastic Patients nanUNKNOWN
Prevalence and Clinical Effect of IDH1/2 Mutations in Patients With Acute Myeloid Leukemia nanUNKNOWN
Vorasidenib Guided by AGX PET in Recurrent/Low-grade Glioma nanNOT_YET_RECRUITING
Detection of IDH2 Mutations and Monitoring Molecular Residual Disease in Patients With AML nanCOMPLETED
Radiomics-Based Visualization and Quantitative Validation of IDH1 Heterogeneity in Gliomas nanACTIVE_NOT_RECRUITING
Monitoring of Neurological Symptoms, Treatment Tolerance, and Quality of Life Using the Resilience PRO Electronic Patient-reported Outcome Application in Patients With IDH-mutated Glioma nanNOT_YET_RECRUITING
Clinical Development of Cancer-Specific MRS Biomarkers in Malignant Gliomas nanCOMPLETED
Patient Voice in the Treatment of Low-grade Gliomas: Use of Patient-reported Outcomes, Vorasidenib and Radiotherapy Compared nanRECRUITING
Surgical Management of Low Grade Glioma nanNOT_YET_RECRUITING
Ivosidenib (TIBSOVO®) Combined With Azacitidine According to Current SmPC nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a IDH3B binder may also engage these)

ProteinNameSimilarity
Q28479 1.000 Q28479 →
Q5RBT4 1.000 Q5RBT4 →
O77784 1.000 O77784 →
Q68FX0 1.000 Q68FX0 →
Q8LFC0 1.000 Q8LFC0 →
P41565 1.000 P41565 →
P70404 1.000 P70404 →
P51553 0.998 P51553 →
P29696 0.997 P29696 →
Q58CP0 0.995 Q58CP0 →
O81796 0.995 O81796 →
O13696 0.995 O13696 →
Q945K7 0.993 Q945K7 →
O14104 0.992 O14104 →
Q93353 0.991 Q93353 →
Q93714 0.990 Q93714 →
Q28480 0.990 Q28480 →
P41564 0.989 P41564 →
P29102 0.989 P29102 →
O94229 0.988 O94229 →
Q99NA5 0.988 Q99NA5 →
P93032 0.988 P93032 →
O13302 0.988 O13302 →
Q6LV25 0.987 Q6LV25 →
Q59985 0.986 Q59985 →
P12382 0.986 P12382 →
Q9XGZ0 0.986 Q9XGZ0 →
Q99KE1 0.986 Q99KE1 →
Q5R678 0.985 Q5R678 →
Q7NUC2 0.985 Q7NUC2 →