Sugi Predict

Sugi Predict / Targets / ILK

ILK

Scaffold protein ILK · Q13418 · ILK on Sugi Atlas →

9,453 patent compounds predicted against ILK, 5,933 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL680380 SCHEMBL680380 1.00 20/20
SCHEMBL686402 SCHEMBL686402 1.00 20/20
SCHEMBL686406 SCHEMBL686406 1.00 20/20
SCHEMBL686474 SCHEMBL686474 1.00 20/20
SCHEMBL686482 SCHEMBL686482 1.00 20/20
SCHEMBL686495 SCHEMBL686495 1.00 20/20
SCHEMBL686521 SCHEMBL686521 1.00 20/20
SCHEMBL686525 SCHEMBL686525 1.00 20/20
SCHEMBL686542 SCHEMBL686542 1.00 20/20
SCHEMBL686556 SCHEMBL686556 1.00 20/20
SCHEMBL686578 SCHEMBL686578 1.00 20/20
SCHEMBL686598 SCHEMBL686598 1.00 20/20
SCHEMBL686711 SCHEMBL686711 1.00 20/20
SCHEMBL686776 SCHEMBL686776 1.00 20/20
SCHEMBL686851 SCHEMBL686851 1.00 20/20
SCHEMBL686860 SCHEMBL686860 1.00 20/20
SCHEMBL686928 SCHEMBL686928 1.00 20/20
SCHEMBL686931 SCHEMBL686931 1.00 20/20
SCHEMBL686955 SCHEMBL686955 1.00 20/20
SCHEMBL686963 SCHEMBL686963 1.00 20/20

Clinical trials — most relevant to ILK by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Study to Evaluate the Possible Antifibrotic Effect of Zinc Sulphate in Chronic HCV Patient Receiving Direct Acting Anti-viral Therapy. PHASE3COMPLETED
Doxycycline in Human Pulmonary Tuberculosis PHASE2COMPLETED
A Clinical Study of Alanyl-Glutamine for Reduction of Post-Myomectomy Adhesions PHASE1/PHASE2COMPLETED
Phase II Dasatinib Study in Advanced Breast Cancer PHASE2COMPLETED
SCARFREE-001: Verteporfin for Scar Prevention PHASE2NOT_YET_RECRUITING
Neoadjuvant Zoledronate and Atorvastatin in Triple Negative Breast Cancer PHASE2COMPLETED
Phase I/II Safety Study of IPI-504 in Relapsed/Refractory Stage IIIb, or Stage IV Non-small Cell Lung Cancer (NSCLC) PHASE1/PHASE2COMPLETED
WJMSCs Anti-inflammatory Therapy in Acute Myocardial Infarction PHASE2UNKNOWN
FAK Inhibitor in Patients With Advanced Solid Tumors PHASE1NOT_YET_RECRUITING
Safety/Biomarker Study of CNTO 95 and Avastin in Solid Tumors PHASE1COMPLETED
A Dose Escalation and Expansion Trial With BYON4228 Alone and in Combination in Patients With Advanced or Metastatic Solid Tumors PHASE1ACTIVE_NOT_RECRUITING
68Ga-NOTA-PRGD2 PET/CT in Patients With Lung Injury and Pulmonary Fibrosis EARLY_PHASE1UNKNOWN
68Ga-BNOTA-PRGD2 PET/CT in Evaluation of Stroke EARLY_PHASE1UNKNOWN
Profiling Gingival Crevicular Fluid β-Catenin Level With 8-OHdG and Total Antioxidants Capacity During Healing of Periodontal Pockets: A 3-month Clinical Trial nanNOT_YET_RECRUITING
Comparative Evaluation of Calcium Silicate-doped Treated Dentin Matrix and Mineral Trioxide Aggregate as Miniature Pulpotomy Biomaterials in Deep Carious Lesions nanNOT_YET_RECRUITING
Angiogenesis and Fibrosis in Aortic Stenosis nanCOMPLETED
Histological and Molecular Mechanisms of Pain in Patient With Chronic Pain From Adhesions nanCOMPLETED
The Roles of Neutrophil Elastase in Lung Cancer nanUNKNOWN
Investigate eNAMPT in Multiple Myeloma Biology and Establish Its Role in Disease Progression nanCOMPLETED
Indoxyl Sulfate Induces Leukocyte-endothelial Interactions Through Up-regulation of ICAM-1 in Acute Kidney Injury nanUNKNOWN
The Activation of Hippo Pathway in Nasal Polyps nanUNKNOWN
Studying the Role of Circulating Tumor Cell Clusters in Patients With High-risk Early Breast Cancer, Study GALIA nanRECRUITING
Angiogenesis and Fibrosis in Myocardial Infarction nanCOMPLETED
Onco4D(TM) Biodynamic Chemotherapy Selection for Bladder Cancer Patients nanUNKNOWN
Association Between Intakes of Protein, Calcium and Milk With Gene Expression and Linear Growth of School Aged Children nanCOMPLETED
Markers of Vascular Calcification in Diabetic Nephropathy in Patients With Diabetic Nephropathy nanUNKNOWN
Immune Cell Response to Stimuli nanRECRUITING
Efficacy and Safety of the Treatment of Primary Membranous Nephropathy: A Randomized Clinical Trial nanUNKNOWN
C-X-C Chemokine Receptor 4 in Chronic Lymphocytic Leukemia nanUNKNOWN
Evaluation of Volume Stable Collagen Matrix in the Regenerative Outcome of Periodontal Intrabony Defects nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a ILK binder may also engage these)

ProteinNameSimilarity
O55222 — 1.000 O55222 →
Q99J82 — 1.000 Q99J82 →
Q3SWY2 — 0.999 Q3SWY2 →
Q5R5V4 — 0.999 Q5R5V4 →
P57044 — 0.999 P57044 →
Q9TZC4 — 0.995 Q9TZC4 →
Q9DF58 — 0.994 Q9DF58 →
Q6P686 — 0.987 Q6P686 →
Q7ZYG4 — 0.987 Q7ZYG4 →
Q8MJ49 — 0.986 Q8MJ49 →
Q95266 — 0.986 Q95266 →
Q03428 — 0.986 Q03428 →
Q03145 — 0.986 Q03145 →
O16544 — 0.986 O16544 →
P08413 — 0.985 P08413 →
A4IGM9 — 0.985 A4IGM9 →
DAPK1 Death-associated protein kinase 1 0.985 landscape →
Q54RB7 — 0.985 Q54RB7 →
Q90344 — 0.985 Q90344 →
P51137 — 0.985 P51137 →
Q80YE7 — 0.985 Q80YE7 →
Q54Y55 — 0.985 Q54Y55 →
B9DHT4 — 0.985 B9DHT4 →
Q09178 — 0.985 Q09178 →
O12990 — 0.985 O12990 →
Q86AT8 — 0.984 Q86AT8 →
Q7JQ32 — 0.984 Q7JQ32 →
P53356 — 0.984 P53356 →
A2XL32 — 0.984 A2XL32 →
A8WPG9 — 0.984 A8WPG9 →