IMMT — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

	Compound	Confidence	Supporting neighbours

Clinical trials — most relevant to IMMT by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Clinical Evaluation of the Effect of Metformin in Sepsis	PHASE3	UNKNOWN
Effect of Montelukast Versus Co Enzyme in Sepsis	PHASE2/PHASE3	COMPLETED
Ubiquinol (Reduced COQ10) for Patients With Sepsis	PHASE2	COMPLETED
Does Clinical Treatment of Mitochondrial Dysfunction Impact Autism Spectrum Disorder (ASD)?	PHASE1	UNKNOWN
Mechanistic Studies of Nicotinamide Riboside in Human Heart Failure	EARLY_PHASE1	ACTIVE_NOT_RECRUITING
Dynamics of Muscle Mitochondria in Type 2 Diabetes (DYNAMMO T2D)	EARLY_PHASE1	COMPLETED
Natural History Study of SLC25A46 Mutation-related Mitochondriopathy	nan	COMPLETED
Abnormalities in the Effects of Insulin and Exercise on Glucose- and Lipid Metabolism in Obesity and Type 2 Diabetes	nan	COMPLETED
Effect of Subtle Energy Transmission and Tao Calligraphy Mindfulness Practice on Mitochondrial DNA in Peripheral Blood Leukocytes	nan	NOT_YET_RECRUITING
Mitigating Mitochondrial RNA Release During Aging to Control Inflammation and Senescence	nan	NOT_YET_RECRUITING
Effects of Chronic Dietary Exposure to Branched Chain Amino Acids	nan	COMPLETED
Exercise Training Effects on Muscle Function in Adults With Mitochondrial Myopathy	nan	RECRUITING
Tissue Sample Study for Mitochondrial Disorders	nan	ENROLLING_BY_INVITATION
Mitochondrial Assessment in Critical Ill Patients in Intensive Care	nan	NOT_YET_RECRUITING
Cardiac Mitochondrial Function in Explanted Human Hearts	nan	UNKNOWN
The Effect of White Tea Consumption on Obesity	nan	COMPLETED
The Impact of Mitochondrial Dysfunction on Human Bone Cell Metabolism and Remodelling	nan	ACTIVE_NOT_RECRUITING
Measuring Protein Turnover in Humans Across the Lifespan by Metabolic Labeling With Deuterium Oxide	nan	RECRUITING
Calf Muscle Strength in Mitochondrial Diseases	nan	COMPLETED
Skeletal Muscle Regeneration in Survivors of Critical Illness: How to Prevent Satellite Cell Failure?	nan	RECRUITING
Choroid Plexus Dysfunction in Neurological Diseases	nan	RECRUITING
Bioenergetics in Surgical Patients	nan	UNKNOWN
Clinical Study of Hydroxytyrosol (HT) in Mitochondrial Diseases	nan	COMPLETED
MERC Proteins in Saliva and GCF in Periodontal Disease (ELISA Study)	nan	COMPLETED
Dynamics of Muscle Mitochondria in Type 2 Diabetes Exercise	nan	COMPLETED
Effects of Acute Energy Deficit and Aerobic Exercise on Muscle Quality	nan	COMPLETED
Regulation of Lymphocyte Anti-tumor Response in Metastatic Patients Treated With the mTOR Inhibitor Everolimus	nan	COMPLETED
North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC)	nan	RECRUITING
Mitoquines in COPD	nan	UNKNOWN
Genetic Diagnosis in Inborn Errors of Metabolism	nan	ENROLLING_BY_INVITATION

Related proteins — ESM-2 sequence neighbours (a IMMT binder may also engage these)

Protein	Name	Similarity
Q8CAQ8	—	1.000	Q8CAQ8 →
Q9ASV5	—	0.984	Q9ASV5 →
Q84WU4	—	0.984	Q84WU4 →
Q2TBU8	—	0.984	Q2TBU8 →
F4HPA7	—	0.983	F4HPA7 →
Q6GQ73	—	0.983	Q6GQ73 →
A1L2I9	—	0.983	A1L2I9 →
Q05090	—	0.982	Q05090 →
Q4R6N3	—	0.982	Q4R6N3 →
U3JAG9	—	0.981	U3JAG9 →
Q5EAU9	—	0.981	Q5EAU9 →
Q96FV9	—	0.981	Q96FV9 →
Q14CX7	—	0.981	Q14CX7 →
B1AY13	—	0.981	B1AY13 →
A1A4I9	—	0.981	A1A4I9 →
A5D796	—	0.981	A5D796 →
STIM1	Stromal interaction molecule 1	0.981	landscape →
P08592	—	0.981	P08592 →
P84903	—	0.981	P84903 →
Q8BWZ3	—	0.981	Q8BWZ3 →
O94915	—	0.981	O94915 →
Q6PGY6	—	0.980	Q6PGY6 →
P12023	—	0.980	P12023 →
Q5EAC6	—	0.980	Q5EAC6 →
USP24	Ubiquitin carboxyl-terminal hydrolase 24	0.980	landscape →
Q80TJ1	—	0.980	Q80TJ1 →
Q6GLR7	—	0.980	Q6GLR7 →
Q8BHR2	—	0.980	Q8BHR2 →
Q9EQS3	—	0.980	Q9EQS3 →
BRAP	BRCA1-associated protein	0.980	landscape →