KIF2C

Kinesin-like protein KIF2C

0 patent compounds predicted against KIF2C, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

	Compound	Confidence	Supporting neighbours

Germline variants in KIF2C on Sugi Variant → ClinVar classifications, population frequency, and predictor agreement (AlphaMissense, SaProt, REVEL) Full KIF2C gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions

Clinical trials — most relevant to KIF2C by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Vinorelbine in Relapsed Platinum Resistant or Refractory C5 High Grade Serous, Endometrioid, or Undifferentiated Primary Peritoneum, Fallopian Tube or Ovarian Cancer	PHASE2	UNKNOWN
Functional Studies of Novel Genes Mutated in Primary Ciliary Dyskinesia II: Genotype to Phenotype	EARLY_PHASE1	COMPLETED
Genetic Study of Patients With Primary Ciliary Dyskinesia	nan	COMPLETED
Biomarker Research in Inherited Movement Disorders	nan	RECRUITING
Investigation of the Genetic Causes of Kallmann Syndrome and Reproductive Disorders	nan	COMPLETED
Classification, Functional Stratification and Biomarkers in Ciliopathy (CILLICORIRCM)	nan	COMPLETED
Core Stability Exercises and Hereditary Ataxia	nan	COMPLETED
Pediatric Evaluation and Registry for Liver Cholestasis in Canada	nan	RECRUITING
Delineating the Molecular Spectrum and the Clinical, Imaging and Neuronal Phenotype of Chopra-Amiel-Gordon Syndrome	nan	RECRUITING
Gait in Rare Diseases	nan	COMPLETED
Registry and Natural History of Epilepsy-Dyskinesia Syndromes	nan	RECRUITING
Clinical Registry Investigating Bardet-Biedl Syndrome	nan	RECRUITING
Mapping Disease Pathways for Biliary Atresia	nan	RECRUITING
Genetic Studies of Strabismus, Congenital Cranial Dysinnervation Disorders (CCDDs), and Their Associated Anomalies	nan	RECRUITING
Natural History Evaluation of Charcot Marie Tooth Disease (CMT) Types CMT1B, CMT2A, CMT4A, CMT4C, and Others	nan	RECRUITING
Integrated Model for Promoting Parenting and Early School Readiness in Pediatrics	nan	COMPLETED
Genetics of Pediatric-Onset Motor Neuron and Neuromuscular Diseases	nan	COMPLETED
Evaluation and Treatment of Pediatric, Developmental, and Genetic Eye Diseases	nan	COMPLETED
Genetics of Primary Ciliary Dyskinesia	nan	COMPLETED
Spastic Paraplegia - Centers of Excellence Research Network	nan	RECRUITING
Exploring a Motor Learning Technique Based on the Mirror Motor Neuron System	nan	COMPLETED
Investigating Phenotypic, Epigenetic, and NeuroGenetic Traits in Rare and Ultra-rare Neurodevelopmental Disorders (Project PENGUIN)	nan	RECRUITING
Structural Validity and Inter-rater Reliabitiliy of the Ataxia Trunk, Lower And Upper Extremity Scale (ATLAS)	nan	NOT_YET_RECRUITING
Result Of Karyotyping in Pediatric Patients With Congenital Anomalies and Developmental Delay	nan	NOT_YET_RECRUITING
PCD New Gene Discovery	nan	COMPLETED
Hereditary Spastic Paraplegia Genomic Sequencing Initiative (HSPseq)	nan	RECRUITING
Diagnosis of Primary Ciliary Dyskinesia	nan	COMPLETED
Neurogenetics Patient Registry	nan	RECRUITING
Pathogenesis of Primary Ciliary Dyskinesia (PCD) Lung Disease	nan	RECRUITING
Long-read Genome Sequencing for the Molecular Diagnosis of Dystonia	nan	RECRUITING

Related proteins — ESM-2 sequence neighbours (a KIF2C binder may also engage these)

Protein	Name	Similarity
Q95LP1	—	1.000	Q95LP1 →
P70096	—	1.000	P70096 →
Q95LT1	—	1.000	Q95LT1 →
Q91637	—	1.000	Q91637 →
Q62909	—	0.999	Q62909 →
Q8C0N1	—	0.997	Q8C0N1 →
Q5R9Y9	—	0.997	Q5R9Y9 →
Q91636	—	0.997	Q91636 →
Q9WV63	—	0.997	Q9WV63 →
Q8S949	—	0.996	Q8S949 →
Q922S8	—	0.996	Q922S8 →
O00139	—	0.995	O00139 →
Q9AWM8	—	0.995	Q9AWM8 →
F4J2M6	—	0.994	F4J2M6 →
Q5ZKV8	—	0.994	Q5ZKV8 →
Q8L7Y8	—	0.994	Q8L7Y8 →
Q2NL05	—	0.994	Q2NL05 →
Q8N4N8	—	0.994	Q8N4N8 →
P28740	—	0.994	P28740 →
Q940B8	—	0.993	Q940B8 →
B9FS33	—	0.993	B9FS33 →
Q6Z9D2	—	0.993	Q6Z9D2 →
L0N7N1	—	0.993	L0N7N1 →
B9FL70	—	0.992	B9FL70 →
Q9H1H9	—	0.992	Q9H1H9 →
Q8W0Y9	—	0.992	Q8W0Y9 →
O59751	—	0.992	O59751 →
B9EUM5	—	0.992	B9EUM5 →
B3H6Z8	—	0.991	B3H6Z8 →
F4JZ68	—	0.991	F4JZ68 →