LAGE3 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

	Compound	Confidence	Supporting neighbours

Clinical trials — most relevant to LAGE3 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
A Study of KRN23 in Pediatric Patients With X-linked Hypophosphatemic Rickets/Osteomalacia	PHASE3	COMPLETED
Cornelia De Lange Syndrome: Assessing Positive Effects of Lithium Treatment	PHASE2/PHASE3	RECRUITING
Optimizing IV Gentamicin in JEB	PHASE1/PHASE2	UNKNOWN
Perinatal Precision Medicine	nan	UNKNOWN
Identification of Genetic Basis of Atrioventricular Conduction Defects: From Congenital Forms to Degenerative Forms	nan	UNKNOWN
Efficacy of Visual and Perceptual Training on Visual Function for Operative Congenital Ectopia Lentis Children	nan	RECRUITING
MEHMO Natural History and Biomarkers	nan	RECRUITING
Decoding Developmental Disorders in Humams	nan	COMPLETED
Genetic Variants in Linear Localized Scleroderma	nan	COMPLETED
Neurovisual Function in CHARGE Syndrome	nan	UNKNOWN
Whole-genome Sequencing Study in Patients With Diminished Ovarian Reserve	nan	UNKNOWN
Investigating the Genetic Basis of Pseudoexfoliation Syndrome, Angle-closure Glaucoma and Primary Open-angle Glaucoma	nan	RECRUITING
NGS Panel of Incomplete Forms of Ocular Albinism	nan	COMPLETED
New Strategies of Genetic Study of Patients With Oculocutaneous Albinism	nan	COMPLETED
Whole Exome Sequencing in Coronary Artery Ectasia	nan	COMPLETED
Idiopathic CD4 Lymphocytopenia	nan	COMPLETED
Fast Exome for Diagnosis of Congenital Conditions in Infants Under 12 Months of Age Hospitalized in Intensive Care Unit	nan	COMPLETED
Clinical Utility of Pediatric Whole Exome Sequencing	nan	COMPLETED
Clinical Utility of Prenatal Whole Exome Sequencing	nan	COMPLETED
Developing a Management Approach for Patients With Late-Onset Pompe Disease	nan	ACTIVE_NOT_RECRUITING
Impact of Elastin Mediated Vascular Stiffness on End Organs	nan	COMPLETED
Registry and Natural History of Epilepsy-Dyskinesia Syndromes	nan	RECRUITING
Classification, Functional Stratification and Biomarkers in Ciliopathy (CILLICORIRCM)	nan	COMPLETED
Natural History Study of Patients With EYS-Associated RP	nan	RECRUITING
Whole Exome and Whole Genome Sequencing for Genotyping of Inherited and Congenital Eye Conditions	nan	RECRUITING
Study of a Candidate Gene Involved in Goldenhar Syndrome.	nan	COMPLETED
Phenotype and Etiology of Pallister-Hall Syndrome	nan	COMPLETED
Inbon Errors of Immunity Attending Assiut University Children&Amp;#39;s Hospital: a Single Center Study	nan	NOT_YET_RECRUITING
Genomic Study of Congenital Malformation	nan	UNKNOWN
Multidimensional Dynamic Early Warning System for Neonatal Necrotizing Enterocolitis: A Multicenter Clinical Study	nan	NOT_YET_RECRUITING

Related proteins — ESM-2 sequence neighbours (a LAGE3 binder may also engage these)

Protein	Name	Similarity
Q9CR70	—	0.949	Q9CR70 →
P78358	—	0.945	P78358 →
A0A0U1RRI6	—	0.939	A0A0U1RRI6 →
P0DPI3	—	0.935	P0DPI3 →
B7E321	—	0.933	B7E321 →
Q147X3	—	0.932	Q147X3 →
A0A0U1RR11	—	0.932	A0A0U1RR11 →
Q12962	—	0.932	Q12962 →
A6NNE9	—	0.931	A6NNE9 →
Q9CUB6	—	0.931	Q9CUB6 →
A6P320	—	0.930	A6P320 →
E9Q0B3	—	0.929	E9Q0B3 →
A1A5B6	—	0.928	A1A5B6 →
Q8K0H5	—	0.928	Q8K0H5 →
Q9BXQ6	—	0.928	Q9BXQ6 →
Q08DX6	—	0.928	Q08DX6 →
Q3TZ87	—	0.927	Q3TZ87 →
Q460M5	—	0.927	Q460M5 →
Q9WU40	—	0.927	Q9WU40 →
P55108	—	0.927	P55108 →
Q6DVA0	—	0.927	Q6DVA0 →
D3YXK1	—	0.926	D3YXK1 →
Q9Y6J9	—	0.926	Q9Y6J9 →
P83369	—	0.926	P83369 →
Q9JLG8	—	0.926	Q9JLG8 →
Q8CBH7	—	0.926	Q8CBH7 →
Q9P244	—	0.925	Q9P244 →
Q99MX7	—	0.925	Q99MX7 →
Q80TG9	—	0.925	Q80TG9 →
F5H4A9	—	0.925	F5H4A9 →