LITAF — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL2014882	1.00	20/20
SCHEMBL2016099	1.00	20/20
SCHEMBL2016271	1.00	20/20
SCHEMBL2016526	1.00	20/20
SCHEMBL2016540	1.00	20/20
SCHEMBL2016558	1.00	20/20
SCHEMBL2016575	1.00	20/20
SCHEMBL2016579	1.00	20/20
SCHEMBL2016610	1.00	20/20
SCHEMBL2016766	1.00	20/20
SCHEMBL2016948	1.00	20/20
SCHEMBL2017055	1.00	20/20
SCHEMBL2017377	1.00	20/20
SCHEMBL2017602	1.00	20/20
SCHEMBL2017724	1.00	20/20
SCHEMBL2017835	1.00	20/20
SCHEMBL2018139	1.00	20/20
SCHEMBL2019006	1.00	20/20
SCHEMBL2019149	1.00	20/20
SCHEMBL2019335	1.00	20/20

Clinical trials — most relevant to LITAF by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Cardiotoxicity in Breast Cancer Patients	PHASE4	RECRUITING
Lepidium Sativum Extract Versus Simvastatin as an Adjunctive Local Delivery Agents to Non-Surgical Periodontal Therapy	PHASE4	COMPLETED
Clinical Study Evaluating the Anticancer Effect of Pentoxiphylline in Patients With Metastatic Colorectal Cancer	PHASE4	UNKNOWN
The Effects of Polymyxin-B Protects on Sepsis Induced Kidney Dysfunction: a Randomized Clinical Trial	PHASE3	COMPLETED
Intestinal Permeability	PHASE2	COMPLETED
Etanercept (Enbrel) to Treat Pain and Swelling After Third Molar Extraction	PHASE2	COMPLETED
L-Carnitine Protective Effect in Nephrotoxicity	PHASE2	RECRUITING
Safety/Efficacy Study of Bovine Intestinal Alkaline Phosphatase in Patients With Moderate to Severe Ulcerative Colitis	PHASE2	COMPLETED
Lipid Infusion in Dialysis Patients With Endotoxemia	PHASE2	COMPLETED
the Influence of Remote Ischemic Preconditioning on Inflammation During Human Endotoxemia	EARLY_PHASE1	COMPLETED
NCF Gene & TNFSF4 in SLE Patients	nan	UNKNOWN
Effect of Alcohol Consumption on Markers of Inflammation	nan	COMPLETED
Role of Sorcin and Annexin A3 in Breast Cancer Patients	nan	UNKNOWN
Ccf mtDNA as a Neurodegenerative Biomarker	nan	UNKNOWN
MicroRNAs and Cytokines in Peri-Implantitis Tissue	nan	UNKNOWN
Cytokines in Papillon-Lefèvre Syndrome	nan	COMPLETED
Unlock the Cell: Castleman's Disease Flow Cytometry Study	nan	COMPLETED
Inflamation, Gut Leakage, Iron Status After 6000m Ergometer Test in Elite Rowers.	nan	COMPLETED
The Association Between Gene Polymorphisms and Infectious Complications After Liver Surgery	nan	COMPLETED
Effects of a Prescription Omega-3 Fatty Acid Concentrate on Induced Inflammation	nan	COMPLETED
2-A-Day Study: Twice a Day Meals Study.	nan	COMPLETED
Gut, Inflammation and Nutrition in Adult Patients After Fontan Operation	nan	COMPLETED
Plasticity and Regeneration of Renal Epithelial Cells	nan	UNKNOWN
Lactoferrin in Treatment of Fe Deficient Anemia In Cirrhosis	nan	UNKNOWN
Evaluation of Serum Follistatin-Like Protein 1 Levels in Behcet's Disease and Its Association With Disease Activity	nan	COMPLETED
Immune Cell Response to Stimuli	nan	RECRUITING
Obesity - Inflammation - Metabolic Disease: Effect of Lactobacillus Casei Shirota	nan	COMPLETED
Functional Implications of TNF	nan	COMPLETED
Genetic Variation and Immune Responses After Injury	nan	UNKNOWN
Novel Biomarkers in Inflammatory Bowel Disease	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a LITAF binder may also engage these)

Protein	Name	Similarity
P0C0T0	—	0.994	P0C0T0 →
Q9JLJ0	—	0.994	Q9JLJ0 →
Q8QGW7	—	0.987	Q8QGW7 →
Q58D45	—	0.980	Q58D45 →
Q6P828	—	0.979	Q6P828 →
Q9DB75	—	0.979	Q9DB75 →
Q5U2U6	—	0.975	Q5U2U6 →
Q9H305	—	0.975	Q9H305 →
Q99N46	—	0.970	Q99N46 →
Q8AVW3	—	0.970	Q8AVW3 →
Q5BJ83	—	0.967	Q5BJ83 →
O95415	—	0.963	O95415 →
Q32L83	—	0.961	Q32L83 →
Q5PPK1	—	0.961	Q5PPK1 →
Q6GMG8	—	0.957	Q6GMG8 →
Q5XIH2	—	0.956	Q5XIH2 →
P28662	—	0.953	P28662 →
Q4R5H7	—	0.941	Q4R5H7 →
Q5RDV6	—	0.939	Q5RDV6 →
Q5R526	—	0.939	Q5R526 →
Q15038	—	0.938	Q15038 →
Q5ZIS9	—	0.937	Q5ZIS9 →
Q9QZC7	—	0.935	Q9QZC7 →
Q969T9	—	0.935	Q969T9 →
A1KXE4	—	0.935	A1KXE4 →
Q5R4K6	—	0.934	Q5R4K6 →
Q3T0K9	—	0.934	Q3T0K9 →
P60486	—	0.934	P60486 →
Q0IHC4	—	0.933	Q0IHC4 →
Q8R478	—	0.933	Q8R478 →