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Sugi Predict / Targets / MBTD1

MBTD1

MBT domain-containing protein 1 · Q05BQ5 · MBTD1 on Sugi Atlas →

12,536 patent compounds predicted against MBTD1, 8,115 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL1085239 SCHEMBL1085239 0.67 8/20
SCHEMBL1085344 SCHEMBL1085344 0.67 8/20
SCHEMBL1085050 SCHEMBL1085050 0.60 8/20
SCHEMBL1085504 SCHEMBL1085504 0.59 8/20
SCHEMBL896913 SCHEMBL896913 0.58 8/20
SCHEMBL723697 SCHEMBL723697 0.57 8/20
SCHEMBL1083716 SCHEMBL1083716 0.51 8/20
Hydrochloric Acid Hydrochloric Acid (SCHEMBL725466) 0.71 7/20
Hydrochloric Acid Hydrochloric Acid (SCHEMBL722840) 0.69 7/20
Hydrochloric Acid Hydrochloric Acid (SCHEMBL723578) 0.67 7/20
SCHEMBL1085145 SCHEMBL1085145 0.56 7/20
SCHEMBL1085278 SCHEMBL1085278 0.56 7/20
SCHEMBL95490 SCHEMBL95490 0.85 6/20
SCHEMBL764630 SCHEMBL764630 0.84 6/20
SCHEMBL590136 SCHEMBL590136 0.79 6/20
SCHEMBL95807 SCHEMBL95807 0.68 6/20
SCHEMBL1085624 SCHEMBL1085624 0.59 6/20
SCHEMBL1031602 SCHEMBL1031602 0.54 6/20
SCHEMBL96138 SCHEMBL96138 0.52 6/20
SCHEMBL724509 SCHEMBL724509 0.52 6/20

Clinical trials — most relevant to MBTD1 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Effect of RVX000222 on Time to Major Adverse Cardiovascular Events in High-Risk T2DM Subjects With CAD PHASE3COMPLETED
Evaluation of the Safety and the Tolerability of a Combination of Two HIV Inducers in Patients With Undetectable Viral Load PHASE1COMPLETED
Single-Dose AAV-MECP2 Safety/Tolerability and Efficacy in Rett Syndrome EARLY_PHASE1ACTIVE_NOT_RECRUITING
Combining Gene Variants to Improve Risk Prediction for Metabolic (Dysfunction)- Associated Fatty Liver Disease and Its Progression to Cirrhosis in Indian Individuals With Type 2 Diabetes nanCOMPLETED
MYT1L Syndrome: a Rare Paediatric Genetic Syndrome Responsible for a Neurodevelopmental Disorder nanRECRUITING
Markers and Mechanisms of Macrovascular Disease in IDDM nanCOMPLETED
Family Myopia Study nanCOMPLETED
Studying DNA and Outcome in Patients With Advanced Colorectal Cancer Treated With Fluorouracil and Oxaliplatin With or Without Bevacizumab on Clinial Trial E-3200 nanCOMPLETED
Genetic Studies of Strabismus, Congenital Cranial Dysinnervation Disorders (CCDDs), and Their Associated Anomalies nanRECRUITING
A Multi-Dimensional Model of cAre and transItion for Patients With cOmplex RAre Diseases nanACTIVE_NOT_RECRUITING
Thermogenic Silencer Regulatory Factors in Humans nanACTIVE_NOT_RECRUITING
Study of a Candidate Gene Involved in Goldenhar Syndrome. nanCOMPLETED
Major Depression and Messenger RNAs nanCOMPLETED
Genetics of Cardiovascular and Neuromuscular Disease nanRECRUITING
Maternal Genes and Epimutations: Beckwith-Wiedemann Syndrome & Reproductive Risks nanRECRUITING
Mapping Novel Disease Genes for Dilated Cardiomyopathy nanCOMPLETED
Diagnosis of RSTS: Identification of the Acetylation Profiles as Epigenetic Markers for Assessing Causality of CREBBP and EP300 Variants. nanUNKNOWN
Muscle Tissue Bank for Muscular Dystrophy nanCOMPLETED
Study of a Large Family With Congenital Mirror Movements : From Underlying Pathophysiology to Culprit Gene Identification PROJET MOMIC nanCOMPLETED
Genetic Biomarkers for the Response to Anti-VEGF (Vascular Endothelial Growth Factor).Treatment in Wet Age-related Macular Degeneration (Wet ARMD) nanCOMPLETED
Use of miRNAs in Growth Hormone Deficiency (GHD) nanUNKNOWN
A Prospective Study on the Application of Liquid Biopsy in the Surveillance of High-risk Population of HCC. nanUNKNOWN
Investigation of Tumor Microenvironment After CRPC Along With Before and After Neoadjuvant Therapy for Prostate Cancer nanUNKNOWN
Autophagy in Systemic Lupus Erythematosus nanUNKNOWN
Emotional Regulation in Children With ND: the Role of Genomic Variation, Proteomic Patterns, and Early Experience nanUNKNOWN
Predisposition Genes in Monogenic Diabetes (DIAMONO) nanCOMPLETED
Identification of Genes and Pathogenesis Involved in Familial Thoracic Aortic Aneurysm nanCOMPLETED
Identification of a New Gene Involved in Hereditary Lipodystrophy nanCOMPLETED
Methylation of DNA in Children and Adolescents With Type 1 Diabetes Mellitus (METHYLDIAB) nanCOMPLETED
Natural History Study of Smith-Magenis Syndrome nanACTIVE_NOT_RECRUITING

Related proteins — ESM-2 sequence neighbours (a MBTD1 binder may also engage these)

ProteinNameSimilarity
Q6P5G3 — 1.000 Q6P5G3 →
Q6DIN3 — 1.000 Q6DIN3 →
Q32N90 — 1.000 Q32N90 →
Q1JQD9 — 0.999 Q1JQD9 →
P59178 — 0.996 P59178 →
Q5R737 — 0.996 Q5R737 →
Q969R5 — 0.996 Q969R5 →
Q3MIF2 — 0.995 Q3MIF2 →
Q9JMD1 — 0.995 Q9JMD1 →
Q9UHJ3 — 0.993 Q9UHJ3 →
Q9JMD2 — 0.993 Q9JMD2 →
Q5DTW2 — 0.986 Q5DTW2 →
Q8R5C8 — 0.985 Q8R5C8 →
Q5E9T7 — 0.984 Q5E9T7 →
Q5ZIJ9 — 0.983 Q5ZIJ9 →
G5EF51 — 0.983 G5EF51 →
Q15326 — 0.983 Q15326 →
B1B1A0 — 0.983 B1B1A0 →
Q92503 — 0.983 Q92503 →
E9PUQ8 — 0.982 E9PUQ8 →
Q95K79 — 0.982 Q95K79 →
Q96BT7 — 0.981 Q96BT7 →
O88509 — 0.981 O88509 →
Q5ZJM3 — 0.981 Q5ZJM3 →
Q08BR4 — 0.980 Q08BR4 →
Q6INA9 — 0.980 Q6INA9 →
KDM5B Lysine-specific demethylase 5B 0.980 landscape →
Q02395 — 0.980 Q02395 →
Q86XP1 — 0.980 Q86XP1 →
Q921C3 — 0.980 Q921C3 →