Sugi Predict
/ Targets
/ MCM2
Top predicted compounds (top 20 by supporting neighbours, then confidence)
| Compound | Confidence | Supporting neighbours |
|---|
Clinical trials — most relevant to MCM2 by text similarity (a relevance ranking, not an exhaustive list)
| Trial | Phase | Status |
|---|
| Clinical and Pharmacoeconomic Assessment of CDK4/6 Inhibitors for Treatment of Breast Cancer in Egypt |
PHASE4 | COMPLETED |
| Cornelia De Lange Syndrome: Assessing Positive Effects of Lithium Treatment |
PHASE2/PHASE3 | RECRUITING |
| Iloprost in Preventing Lung Cancer in Patients at High Risk for This Disease |
PHASE2 | COMPLETED |
| A Phase 1/2 Trial of SRA737 in Subjects With Advanced Cancer |
PHASE1/PHASE2 | COMPLETED |
| Trial of Topotecan With VX-970 (M6620), an ATR Kinase Inhibitor, in Small Cell Cancers and Extrapulmonary Small Cell Cancers |
PHASE1/PHASE2 | COMPLETED |
| Everolimus in CDK12-Deficient Metastatic Colorectal Cancer (EVER-RECODE) |
PHASE1/PHASE2 | NOT_YET_RECRUITING |
| A Study of PARG Inhibitor ETX-19477 in Patients With Advanced Solid Malignancies |
PHASE1/PHASE2 | RECRUITING |
| M7824 and Topotecan or Temozolomide in Relapsed Small Cell Lung Cancers |
PHASE1/PHASE2 | COMPLETED |
| A Study of CHeckpoint Inhibitors in Men With prOgressive Metastatic Castrate Resistant Prostate Cancer Characterized by a Mismatch Repair Deficiency or Biallelic CDK12 Inactivation |
PHASE2 | ACTIVE_NOT_RECRUITING |
| A Phase 1/2 Trial SRA737 in Combination With Gemcitabine and Cisplatin or Gemcitabine Alone in Advanced Cancer Subjects |
PHASE1/PHASE2 | COMPLETED |
| Lurbinectedin With Berzosertib, an ATR Kinase Inhibitor in Small Cell Cancers and High-Grade Neuroendocrine Cancers |
PHASE1/PHASE2 | ACTIVE_NOT_RECRUITING |
| Testing the Addition of an Anti-cancer Drug, Abemaciclib, to the Usual Chemotherapy Treatment (Gemcitabine) for Soft Tissue Sarcoma |
PHASE1/PHASE2 | RECRUITING |
| Clinical Study of Previously Untreated Patients With Malignant Melanoma |
PHASE2 | COMPLETED |
| Safety and Efficacy of BMS-986504 in Unresectable Malignant Peripheral Nerve Sheath Tumor |
PHASE1/PHASE2 | NOT_YET_RECRUITING |
| Veliparib (ABT-888), an Oral PARP Inhibitor, and VX-970, an ATR Inhibitor, in Combination With Cisplatin in People With Refractory Solid Tumors |
PHASE1 | COMPLETED |
| Open-Label, Randomised, Multi-Drug, Biomarker-Directed, Phase 1b Study in Pts w/ Muscle Invasive Bladder Cancer |
PHASE1 | ACTIVE_NOT_RECRUITING |
| AZD1775 for Advanced Solid Tumors |
PHASE1 | COMPLETED |
| Nucleoside Therapy in Patients With Telomere Biology Disorders |
PHASE1 | RECRUITING |
| Role of Geminin and Mcm-2 in Prognosis of Renal Cell Carcinoma |
nan | UNKNOWN |
| Effect of Adenovirus E1A Oncogene on DNA Replication Dynamics |
nan | UNKNOWN |
| Plasma Triglyceride Lipolysis in Multifactorial Chylomicronemia |
nan | COMPLETED |
| Study of the Effect of Innate on the Inflammatory Response to Endotoxin |
nan | RECRUITING |
| Telomeres Length in Israeli Fibrotic ILD Patients |
nan | ENROLLING_BY_INVITATION |
| Microcephaly Genetic Deficiency in Neural Progenitors |
nan | COMPLETED |
| Plant Extracted Natural Compounds Impact on Stage IV Breast Cancer Survival Time and Remission. |
nan | UNKNOWN |
| Study of Skin Cells That Stop Replicating (Senescent) During Wound Healing |
nan | COMPLETED |
| Prevalence of Constitutional Mismatch-repair Deficiency Among Suspected Neurofibromatosis Type 1/Legius Syndrome Children Without a Malignancy and Without a NF1 or SPRED1 Mutation |
nan | UNKNOWN |
| A Clinical Evaluation of Everolimus Eluting Coronary Stents in the Treatment of Patients With ST-segment Elevation Myocardial Infarction: EXAMINATION Study |
nan | COMPLETED |
| Germline Alterations of Tumor Susceptibility Genes in New York Cancer Patients |
nan | ACTIVE_NOT_RECRUITING |
| Genetic Analysis of Familial Melanoma |
nan | COMPLETED |
Related proteins — ESM-2 sequence neighbours (a MCM2 binder may also engage these)