MCU

Calcium uniporter protein, mitochondrial · Q8NE86 · MCU on Sugi Atlas →

0 patent compounds predicted against MCU, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to MCU by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Motor Function Efficacy of Pharmacological Treatments Targeting Energy Metabolism, in Parkinson's Patients PHASE4UNKNOWN
Clinical Evaluation of the Effect of Metformin in Sepsis PHASE3UNKNOWN
Levosimendan in Acute Decompensated Heart Failure PHASE2/PHASE3NOT_YET_RECRUITING
Renal Transplantation and Inhaled Anesthetic Sevoflurane (SEVOREIN) PHASE3COMPLETED
Mitochondrial Dysfunction in the Pathophysiology and Treatment of Bipolar Disorder PHASE2WITHDRAWN
Calcium Electroporation for Head and Neck Cancer PHASE1UNKNOWN
Influence of Morphine or Ketamine or Saline Applied During In-hospital Cardiopulmonary Resuscitation on Early Survival PHASE1UNKNOWN
Trial of Oxaloacetate in ALS PHASE1COMPLETED
Dynamics of Muscle Mitochondria in Type 2 Diabetes (DYNAMMO T2D) EARLY_PHASE1COMPLETED
Combined Effect of Exercise Intensity With Nutritional Supplementation on Skeletal Muscle Function nanCOMPLETED
Predicting Pancreatic Necrosis Using mitDNA nanUNKNOWN
Transgenerational Metabolic-Immune Biomarkers of Neurological and Neurodevelopmental Disorders nanRECRUITING
Control of the Opening of mPTP by Ex Vivo Measurements on Permeabilized Muscle Fibers (COMMEF) nanUNKNOWN
Mitochondrial Assessment in Critical Ill Patients in Intensive Care nanNOT_YET_RECRUITING
Preliminary Study for Identification of Calcium-Binding Proteins in the Serum in Various Metabolic Bone Disorders nanUNKNOWN
Manganese-Enhanced Magnetic Resonance Imaging (MEMRI) in Ischaemic, Inflammatory and Takotsubo Cardiomyopathy (MEMORY) nanCOMPLETED
Genetic Variations That Increase the Risk for Calcium Kidney Stones: a Family-based Study nanCOMPLETED
MERC Proteins in Saliva and GCF in Periodontal Disease (ELISA Study) nanCOMPLETED
Role of Amino Acids and Genetic Disorder in Pathogenesis of Heart Failure nanUNKNOWN
Carnosine Supplementation on Quantity/Quality of Oral Salivae. nanUNKNOWN
Effect of Subtle Energy Transmission and Tao Calligraphy Mindfulness Practice on Mitochondrial DNA in Peripheral Blood Leukocytes nanNOT_YET_RECRUITING
Dynamics of Muscle Mitochondria in Type 2 Diabetes Exercise nanCOMPLETED
Natural History Study of SLC25A46 Mutation-related Mitochondriopathy nanCOMPLETED
Mitoquines in COPD nanUNKNOWN
Calf Muscle Strength in Mitochondrial Diseases nanCOMPLETED
Tissue Sample Study for Mitochondrial Disorders nanENROLLING_BY_INVITATION
Natural History Study of FDXR Mutation-related Mitochondriopathy nanCOMPLETED
MITOMICS : a Multi-OMICS Approach for the Diagnosis of Mitochondrial Diseases nanRECRUITING
The Natural History of Mitochondrial Diseases nanRECRUITING
Nicotinamide Riboside and Mitochondrial Biogenesis nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a MCU binder may also engage these)

ProteinNameSimilarity
Q3UMR5 1.000 Q3UMR5 →
Q08BI9 0.973 Q08BI9 →
A9JRA0 0.973 A9JRA0 →
A3KN28 0.972 A3KN28 →
Q68FW3 0.971 Q68FW3 →
Q8K4P7 0.970 Q8K4P7 →
Q91YY4 0.969 Q91YY4 →
Q90YH8 0.967 Q90YH8 →
Q9Y2S7 0.967 Q9Y2S7 →
Q1LZ96 0.965 Q1LZ96 →
Q8TDW4 0.965 Q8TDW4 →
Q5ZKS6 0.965 Q5ZKS6 →
O75208 0.965 O75208 →
Q9BPX6 0.964 Q9BPX6 →
Q91VA6 0.964 Q91VA6 →
Q80YV4 0.963 Q80YV4 →
Q68FT1 0.963 Q68FT1 →
Q00PJ0 0.963 Q00PJ0 →
Q8N5M1 0.963 Q8N5M1 →
P83094 0.963 P83094 →
Q108U3 0.963 Q108U3 →
Q08BT5 0.963 Q08BT5 →
Q9R1D7 0.963 Q9R1D7 →
Q8BWQ6 0.962 Q8BWQ6 →
Q6NYU2 0.962 Q6NYU2 →
Q5R5F8 0.962 Q5R5F8 →
Q4A1L5 0.962 Q4A1L5 →
Q8IWV8 0.962 Q8IWV8 →
F1LTE0 0.962 F1LTE0 →
Q5E943 0.962 Q5E943 →