MDN1 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL29355149	1.00	1/20
SCHEMBL30197784	1.00	1/20
SCHEMBL26928536	0.57	1/20
SCHEMBL30373592	0.55	1/20
SCHEMBL21143306	0.55	1/20
SCHEMBL31046829	0.55	1/20

Clinical trials — most relevant to MDN1 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Strategies to Reduce Organic Muscle Atrophy in the Intensive Care Unit	PHASE2/PHASE3	WITHDRAWN
Biologic Correlative Taxotere/AC	PHASE2	COMPLETED
Peptide Vaccine Focusing on Prevention of the Recurrence for Bladder Cancer	PHASE2	UNKNOWN
Effects of Vitamin D Supplementation on Muscle Protein Synthesis	PHASE2	COMPLETED
Novel Peptide Vaccination for Patients With Advanced Bladder Cancer	PHASE1	COMPLETED
Study of ABT-751 in Patients With Refractory Hematologic Malignancies	PHASE1	COMPLETED
Dynamics of Muscle Mitochondria in Type 2 Diabetes (DYNAMMO T2D)	EARLY_PHASE1	COMPLETED
Long Non Coding RNA HOTAIR and Midkine as Biomarkers in Thyroid Cancer	nan	UNKNOWN
The Effect of Blood Flow Restriction (Bfr) Exercise on Acute Systemic Myokine Levels in Healthy Trained Men	nan	UNKNOWN
Development of Non-invasive Prenatal Test for Microdeletion and Other Genetic Syndromes Based on Cell Free DNA	nan	COMPLETED
Disability Severity Scale (DSI) and Hereditary Motor and Sensory Neuropathy Overall Disability Scale (HMSN-R-ODS)	nan	COMPLETED
Predisposition Genes in Monogenic Diabetes (DIAMONO)	nan	COMPLETED
Dynamics of Muscle Mitochondria in Type 2 Diabetes Exercise	nan	COMPLETED
Nuclear Myosin VI - a Therapeutic Target in Breast Cancer	nan	UNKNOWN
Molecular Analysis of Patients With Neuromuscular Disease	nan	RECRUITING
Value of Cortactin Expression in Invasive and Non-invasive Urinary Bladder Urothelial Carcinoma in Egyptian Population	nan	COMPLETED
Role of Sorcin and Annexin A3 in Breast Cancer Patients	nan	UNKNOWN
Mapping Novel Disease Genes for Dilated Cardiomyopathy	nan	COMPLETED
Major Depression and Messenger RNAs	nan	COMPLETED
Natural History Evaluation of Charcot Marie Tooth Disease (CMT) Types CMT1B, CMT2A, CMT4A, CMT4C, and Others	nan	RECRUITING
A Study on Risk Mutations of Vulnerability Genes of Schizophrenia	nan	UNKNOWN
Characterization of Microbiological and Genetic Features in Prostate Cancer and Their Association with Disease Stage	nan	ENROLLING_BY_INVITATION
Measuring Protein Turnover in Humans Across the Lifespan by Metabolic Labeling With Deuterium Oxide	nan	RECRUITING
Genetic Identification (ID) of Segmental Dysplastic Nevi	nan	WITHDRAWN
Skeletal Muscle Regeneration in Survivors of Critical Illness: How to Prevent Satellite Cell Failure?	nan	RECRUITING
Thoracic Aortic Dilatation Syndromes	nan	COMPLETED
Markers and Mechanisms of Macrovascular Disease in IDDM	nan	COMPLETED
Impact of Sensory, Motor and Vestibular Deficit on the Postural Stability of CMT Patients	nan	UNKNOWN
Clinical Outcome Study for Dysferlinopathy	nan	UNKNOWN
Aberrant Gene Expression Prostate Carcinoma	nan	ACTIVE_NOT_RECRUITING

Related proteins — ESM-2 sequence neighbours (a MDN1 binder may also engage these)

Protein	Name	Similarity
P0CI65	—	0.989	P0CI65 →
A0JM23	—	0.985	A0JM23 →
Q6AZT7	—	0.985	Q6AZT7 →
DNAJC13	DnaJ homolog subfamily C member 13	0.985	landscape →
Q7TNH6	—	0.984	Q7TNH6 →
Q6ZS30	—	0.984	Q6ZS30 →
Q6PIY5	—	0.984	Q6PIY5 →
O02697	—	0.984	O02697 →
Q6PJI9	—	0.983	Q6PJI9 →
Q6P5D8	—	0.983	Q6P5D8 →
Q8VCZ6	—	0.983	Q8VCZ6 →
Q9ULT8	—	0.983	Q9ULT8 →
Q9CXF7	—	0.982	Q9CXF7 →
Q7Z494	—	0.982	Q7Z494 →
Q8CEC0	—	0.982	Q8CEC0 →
Q8VDY4	—	0.982	Q8VDY4 →
Q91VB4	—	0.981	Q91VB4 →
B1AY13	—	0.981	B1AY13 →
Q5ZL91	—	0.981	Q5ZL91 →
Q9ESE1	—	0.981	Q9ESE1 →
Q4QQS8	—	0.981	Q4QQS8 →
E9PUQ8	—	0.981	E9PUQ8 →
A6NNW6	—	0.981	A6NNW6 →
E9Q956	—	0.981	E9Q956 →
Q96NW4	—	0.981	Q96NW4 →
Q5R5T0	—	0.981	Q5R5T0 →
Q95LY5	—	0.981	Q95LY5 →
Q92503	—	0.981	Q92503 →
O95876	—	0.981	O95876 →
Q5REW9	—	0.981	Q5REW9 →