MED12

Mediator of RNA polymerase II transcription subunit 12 · Q93074 · MED12 on Sugi Atlas →

0 patent compounds predicted against MED12, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to MED12 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Clinical and Pharmacoeconomic Assessment of CDK4/6 Inhibitors for Treatment of Breast Cancer in Egypt PHASE4COMPLETED
PhII 5-Azacytidine Plus Valproic Acid and Eventually Atra in Intermediate II and High Risk MDS PHASE2COMPLETED
A Phase Ib/II Clinical Study Evaluating the Safety and Efficacy of Tislelizumab in Combination With Golidocitinib and Selinexor for the Treatment of R/R NKTCL PHASE1/PHASE2RECRUITING
Phase I Dose Finding and Proof-of-concept Study of Panobinostat With Standard Dose Cytarabine and Daunorubicin for Untreated Acute Myeloid Leukemia or Advanced Myelodysplastic Syndrome PHASE1COMPLETED
Evaluation of the Safety and the Tolerability of a Combination of Two HIV Inducers in Patients With Undetectable Viral Load PHASE1COMPLETED
Studying The Role of Key Epigenetic Mediators in Breast Cancer Patients nanRECRUITING
Spironolactone and XPB-1 Integrity in the TFIIH Complex nanENROLLING_BY_INVITATION
Cytomegalovirus (CMV) MicroRNA Expression in Vivo and Immune Evasion Correlates nanCOMPLETED
Association of SNPs in Long Intergenic Noncoding RNA 00511 (LINC00511) With Breast Cancer Among the Egyptian Population nanCOMPLETED
PHF19 Gene Expression and EZH2 Gene Deletion in Acute Myeloid Leukemia nanUNKNOWN
Maximizing Mechanisms of Muscle Hypertrophy to Combat Sarcopenia in Older Adults nanCOMPLETED
Studying Genes in Samples From Younger Patients With Relapsed Acute Lymphoblastic Leukemia nanCOMPLETED
miR-155 Expression in Episodic and Chronic Migraine nanUNKNOWN
Endolymphatic Sac Tumors in a Population of Patients With Von Hippel-Lindau Disease:The Natural History and Pathobiology, and a Prospective Non-Randomized Clinical Trial of Hearing Preservation Surgery in Patients With Early Stage Endolymphatic Sac Tumors nanCOMPLETED
Effect of Adenovirus E1A Oncogene on DNA Replication Dynamics nanUNKNOWN
Methylation of DNA in Children and Adolescents With Type 1 Diabetes Mellitus (METHYLDIAB) nanCOMPLETED
The Molecular Pathogenesis Study of Cataract nanUNKNOWN
Aberrant Splicings Due to Microsatellite Instability in Colorectal Cancer : Physiopathological and Clinical Impact nanUNKNOWN
Recombinant Interferon Alfa-2b in Treating Patients With Melanoma nanCOMPLETED
The Difference of microRNA and Circulating Tumor Cells in Blood Among Cancer Patients With Immunotherapy nanRECRUITING
Gene Expression Of Suppressor Of Cytokines in In Cutaneous Warts nanCOMPLETED
Mesenchymal Stem Cells in NPM1 Mutated Low Risk Acute Myeloid Leukemia: a Study of the Tumor Microenvironment and Its Contribution to the Outcome nanCOMPLETED
Prevalence of Constitutional Mismatch-repair Deficiency Among Suspected Neurofibromatosis Type 1/Legius Syndrome Children Without a Malignancy and Without a NF1 or SPRED1 Mutation nanUNKNOWN
Long Non-coding RNAs and Their Role on Epigenome as Diagnostic Markers in Childhood Acute Lymphoblastic Leukemia of T Cells. nanUNKNOWN
Immune Interactions in Severe Asthma nanCOMPLETED
Role of SF3B1 Mutation in Assessment of Acute and Chronic Lymphatic Leukemia nanNOT_YET_RECRUITING
X-chromosome Inactivation, Epigenetics and the Transcriptome nanCOMPLETED
Impact of Air Quality on the Effectiveness of Standard of Care Therapy in Children With Autism Spectrum Disorder: A Prospective Longitudinal Study nanNOT_YET_RECRUITING
LINC00511/miR-185-3p Axis and miR-301a-3p Markers for Breast Cancer Diagnosis nanCOMPLETED
Steroid Treatment of Idiopathic Nephrotic Syndrome nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a MED12 binder may also engage these)

ProteinNameSimilarity
Q5RCU2 1.000 Q5RCU2 →
A2AGH6 1.000 A2AGH6 →
Q2QCI8 1.000 Q2QCI8 →
Q7YQK8 1.000 Q7YQK8 →
Q86YW9 1.000 Q86YW9 →
Q8BQM9 1.000 Q8BQM9 →
Q5F3M0 0.998 Q5F3M0 →
Q2PW47 0.996 Q2PW47 →
Q99K74 0.994 Q99K74 →
Q4V8B3 0.993 Q4V8B3 →
Q6ZQ08 0.992 Q6ZQ08 →
CNOT1 CCR4-NOT transcription complex subunit 1 0.992 landscape →
O94915 0.992 O94915 →
Q6P4S8 0.992 Q6P4S8 →
A5GFY4 0.990 A5GFY4 →
Q8R1A4 0.990 Q8R1A4 →
Q6PI53 0.990 Q6PI53 →
P86411 0.990 P86411 →
P21359 0.989 P21359 →
A0JP85 0.989 A0JP85 →
O75448 0.989 O75448 →
Q9VW47 0.989 Q9VW47 →
A1A5H6 0.989 A1A5H6 →
Q2PPJ7 0.989 Q2PPJ7 →
O88480 0.989 O88480 →
A5D794 0.989 A5D794 →
B1AY13 0.988 B1AY13 →
Q9Y3R5 0.988 Q9Y3R5 →
Q96N67 0.988 Q96N67 →
Q80TJ1 0.988 Q80TJ1 →